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Pharmaceutical Biology Volume 55, 2017 - Issue 1
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Research Article

Anti-inflammatory and anticancer effects of flavonol glycosides from Diplotaxis harra through GSK3β regulation in intestinal cells

Imen Nasria Laboratoire de Chimie des Substances Naturelles, UR11-ES74, Faculté des Sciences de Sfax, Université de Sfax, Sfax, BP, Tunisie; ;b IRSD, Université de Toulouse, INSERM, INRA, ENVT, UPS, Toulouse, France;
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Rachid Chawecha Laboratoire de Chimie des Substances Naturelles, UR11-ES74, Faculté des Sciences de Sfax, Université de Sfax, Sfax, BP, Tunisie; ;c UMR 152 Pharma-Dev, Université de Toulouse, IRD, UPS, France;
,
Cynthia Girardic UMR 152 Pharma-Dev, Université de Toulouse, IRD, UPS, France;
,
Emmanuel Masb IRSD, Université de Toulouse, INSERM, INRA, ENVT, UPS, Toulouse, France; ;d Service de Gastroentérologie, Hépatologie et Nutrition, Hôpital des Enfants, Toulouse, France
,
Audrey Ferrandb IRSD, Université de Toulouse, INSERM, INRA, ENVT, UPS, Toulouse, France;
,
Nathalie Vergnolleb IRSD, Université de Toulouse, INSERM, INRA, ENVT, UPS, Toulouse, France;
,
Nicolas Fabrec UMR 152 Pharma-Dev, Université de Toulouse, IRD, UPS, France;
,
Raoudha Mezghani-Jarrayaa Laboratoire de Chimie des Substances Naturelles, UR11-ES74, Faculté des Sciences de Sfax, Université de Sfax, Sfax, BP, Tunisie;
&
Claire Racaud-Sultanb IRSD, Université de Toulouse, INSERM, INRA, ENVT, UPS, Toulouse, France; Correspondence[email protected]
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Pages 124-131 | Received 06 Jun 2016, Accepted 25 Aug 2016, Published online: 22 Sep 2016

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Maria Fernanda Taviano, Sonia Núñez, Adrián Millán-Laleona, Concetta Condurso, Antonella Verzera, Maria Merlino, Monica Ragusa, Natalizia Miceli & Víctor López. (2022) Volatile composition, antidiabetic, and anti-obesity potential of Brassica incana leaf and flowering top extracts. Pharmaceutical Biology 60:1, pages 1994-2001.
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Li-Jin Jiao, Wei-Dong Wang, Yan-Duo Tao, Yun Shao, Li-Juan Mei, Zeng-Gen Liu, Qi-Lan Wang & Jun Dang. (2018) 8-isopentenyl isoflavone derivatives from the whole herb of Sphaerophysa salsula. Natural Product Research 32:21, pages 2542-2546.
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Zahra Salimizadeh, Sattar Tahmasebi Enferadi, Tayebeh Majidizadeh & Frouzandeh Mahjoubi. (2024) Cytotoxicity of alkaloids isolated from Peganum harmala seeds on HCT116 human colon cancer cells. Molecular Biology Reports 51:1.
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Natale Badalamenti, Assunta Napolitano, Maurizio Bruno, Roberta Pino, Rosa Tundis, Vincenzo Ilardi, Monica Rosa Loizzo & Sonia Piacente. (2024) Chemical Profile and Healthy Properties of Sicilian Diplotaxis harra subsp. crassifolia (Raf.) Maire. Molecules 29:11, pages 2450.
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Hong Wang, Lijia Chen, Binrui Yang, Jun Du, Liang Chen, Yiming Li & Fujiang Guo. (2023) Structures, Sources, Identification/Quantification Methods, Health Benefits, Bioaccessibility, and Products of Isorhamnetin Glycosides as Phytonutrients. Nutrients 15:8, pages 1947.
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Atallah F. Ahmed, Zhi-Hong Wen, Ahmed H. Bakheit, Omer A. Basudan, Hazem A. Ghabbour, Abdullah Al-Ahmari & Chien-Wei Feng. (2022) A Major Diplotaxis harra-Derived Bioflavonoid Glycoside as a Protective Agent against Chemically Induced Neurotoxicity and Parkinson’s Models; In Silico Target Prediction; and Biphasic HPTLC-Based Quantification. Plants 11:5, pages 648.
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Claire Racaud-Sultan & Nathalie Vergnolle. (2021) GSK3β, a Master Kinase in the Regulation of Adult Stem Cell Behavior. Cells 10:2, pages 225.
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Tezz Quon, Li-Chiung Lin, Amlan Ganguly, Andrew B. Tobin & Graeme Milligan. (2020) Therapeutic Opportunities and Challenges in Targeting the Orphan G Protein-Coupled Receptor GPR35. ACS Pharmacology & Translational Science 3:5, pages 801-812.
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Li Jin Jiao, Wei Dong Wang, Yan Duo Tao, Yun Shao, Li Juan Mei, Zeng Gen Liu, Qi Lan Wang & Jun Dang. (2018) Two new stilbenoids from the whole herb of Sphaerophysa salsula. Phytochemistry Letters 27, pages 139-142.
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Hui-Feng Chen, Ri-Zhen Huang, Bo Zuo, Lan-Ju Ji, Zhi-Jian Mo & Zhi-Xin Liao. (2017) Anti-proliferative Activities of Two Flavonols with Unsubstituted B-ring from the Leaves of Platanus acerifolia . Natural Product Communications 12:11, pages 1934578X1701201.
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Lijin Jiao, Yanduo Tao, Weidong Wang, Yun Shao, Lijuan Mei, Qilan Wang & Jun Dang. (2017) Preparative isolation of flavonoid glycosides from Sphaerophysa salsula using hydrophilic interaction solid‐phase extraction coupled with two‐dimensional preparative liquid chromatography . Journal of Separation Science 40:19, pages 3808-3816.
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