3-Hydroxy-4,7-megastigmadien-9-one, isolated from Ulva pertusa, attenuates TLR9-mediated inflammatory response by down-regulating mitogen-activated protein kinase and NF-κB pathways

Irshad AliSchool of Medicine and Brain Korea 21 PLUS Program, Jeju National University, Jeju, South Korea; ;Institute of Medical Science, Jeju National University, Jeju, South Korea;

Zahid ManzoorSchool of Medicine and Brain Korea 21 PLUS Program, Jeju National University, Jeju, South Korea; ;Institute of Medical Science, Jeju National University, Jeju, South Korea;

Jung-Eun KooSchool of Medicine and Brain Korea 21 PLUS Program, Jeju National University, Jeju, South Korea; ;Institute of Medical Science, Jeju National University, Jeju, South Korea;

Jung-Eun KimDepartment of Chemistry and Cosmetics, College of Natural Sciences, Jeju National University, Jeju, South Korea

Sang-Hee ByeonDepartment of Chemistry and Cosmetics, College of Natural Sciences, Jeju National University, Jeju, South Korea

Eun-Sook YooSchool of Medicine and Brain Korea 21 PLUS Program, Jeju National University, Jeju, South Korea; ;Institute of Medical Science, Jeju National University, Jeju, South Korea;

Hee-Kyoung KangSchool of Medicine and Brain Korea 21 PLUS Program, Jeju National University, Jeju, South Korea; ;Institute of Medical Science, Jeju National University, Jeju, South Korea;

Jin-Won HyunSchool of Medicine and Brain Korea 21 PLUS Program, Jeju National University, Jeju, South Korea; ;Institute of Medical Science, Jeju National University, Jeju, South Korea;

Nam-Ho LeeDepartment of Chemistry and Cosmetics, College of Natural Sciences, Jeju National University, Jeju, South Korea

Young-Sang KohSchool of Medicine and Brain Korea 21 PLUS Program, Jeju National University, Jeju, South Korea; ;Institute of Medical Science, Jeju National University, Jeju, South Korea; Correspondence[email protected]

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3-Hydroxy-4,7-megastigmadien-9-one, isolated from Ulva pertusa, attenuates TLR9-mediated inflammatory response by down-regulating mitogen-activated protein kinase and NF-κB pathways

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3-Hydroxy-4,7-megastigmadien-9-one, isolated from Ulva pertusa, attenuates TLR9-mediated inflammatory response by down-regulating mitogen-activated protein kinase and NF-κB pathways

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