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Review Article

A systematic review of the active saikosaponins and extracts isolated from Radix Bupleuri and their applications

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Pages 620-635 | Received 13 Jun 2016, Accepted 15 Nov 2016, Published online: 12 Dec 2016

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Read on this site (8)

Lun Tan, Xianzhi Sun, Jingjing Li, Qingfeng Wang, Zhao Zhuo, Yu Li, Yanjing Su, Caiyun Fan & Jianbo Cheng. (2023) Effects of bupleurum extract on the haematological, mineral, and hormonal profiles of heat-stressed dairy cows. Italian Journal of Animal Science 22:1, pages 51-58.
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Paola Maccioni, Young-Won Chin, Federico Corelli, Hak Cheol Kwon & Giancarlo Colombo. (2023) Reducing effect of intragastrically administered saikosaponin A on alcohol and sucrose self-administration in rats. Natural Product Research 37:24, pages 4256-4260.
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Shujuan Huang, Maoxiang Cui, Rufeng Wang, Guiran Yang, Ning Wang, Lijun Cui & Guang Ma. (2023) Combined treatment with Prunella vulgaris and Radix bupleuri activated the Bax/Bcl-2 and Caspase-3 signal pathways in papillary thyroid carcinoma cells. Nucleosides, Nucleotides & Nucleic Acids 42:9, pages 731-742.
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Carla Lobina, Jung Hwan Lee, Pisey Pel, Young-Won Chin, Hak Cheol Kwon & Giancarlo Colombo. (2023) Analgesic effects of saikosaponin A in a rat model of chronic inflammatory pain. Natural Product Research 37:16, pages 2732-2736.
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Piao Zhou, Wei Shi, Xiao-Yan He, Quan-Yu Du, Fei Wang & Jing Guo. (2021) Saikosaponin D: review on the antitumour effects, toxicity and pharmacokinetics. Pharmaceutical Biology 59:1, pages 1478-1487.
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Hongfang Li, Yunyan Tang, Yang Wang, Weipeng Wei, Chengchen Yin & Fushang Tang. (2020) Effects of Saikosaponin D on CYP1A2 and CYP2D6 in HepaRG Cells. Drug Design, Development and Therapy 14, pages 5251-5258.
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Cui Tang, Qiachi Fu, Xia Chen, Yang Hu, Helen Renaud, Chong Ma, Tai Rao, Yao Chen, Zhirong Tan, Curtis D. Klaassen, Shuyun Shi & Ying Guo. (2020) The biotransformation of Bupleuri Radix by human gut microbiota. Xenobiotica 50:9, pages 1011-1022.
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Zhi Chen, Si-Yong Ye & Rong-Gang Zhu. (2020) The extraordinary transformation of traditional Chinese medicine: processing with liquid excipients. Pharmaceutical Biology 58:1, pages 561-573.
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