2,350
Views
37
CrossRef citations to date
0
Altmetric
Research Article

Determination of dihydromyricetin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study

, , &
Pages 657-662 | Received 24 Jun 2016, Accepted 26 Nov 2016, Published online: 12 Dec 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Hongchuan Liu, Huaihuai Dong, Liangjun Guo, Yongsheng Jin & Lihong Liu. (2023) The Effect of Dihydromyricetin on the Pharmacokinetics of Fluconazole in Sprague-Dawley Rat Plasma, Based on High-Performance Liquid Chromatography–Tandem Mass Spectrometry. Drug Design, Development and Therapy 17, pages 2657-2667.
Read now
Yixiang Huang, Junyong Zhao, Wei Jian & Gang Wang. (2018) Effects of verapamil on the pharmacokinetics of dihydromyricetin in rats and its potential mechanism. Xenobiotica 48:8, pages 839-844.
Read now
Jin Peng, Jian Zhang, Li Zhang, Yonggang Tian, Yahong Li & Lujun Qiao. (2018) Dihydromyricetin improves vascular hyporesponsiveness in experimental sepsis via attenuating the over-excited MaxiK and KATP channels. Pharmaceutical Biology 56:1, pages 344-350.
Read now

Articles from other publishers (34)

Yimei Zheng, Boyu Chen, Xuanxiang Huang, Xiamei Tao, Chao Ai, Yanan Zhao, Peng Liang & Lei Chen. (2024) A designed self-microemulsifying delivery system: Stability and Anti-inflammation in vivo enhancement of dihydromyricetin. Journal of Functional Foods 118, pages 106266.
Crossref
Haolin Zhang, Jose Luis Quiles & Hui Cao. 2023. Handbook of Dietary Flavonoids. Handbook of Dietary Flavonoids 1 30 .
Si-Yu Gui, Xin-Chen Wang, Zhi-Hao Huang, Mei-Mei Li, Jia-Hao Wang, Si-Yin Gui, Gan-Hua Zhang, Yao Lu, Li-Ming Tao, Hai-Sheng Qian & Zheng-Xuan Jiang. (2023) Nanoscale coordination polymer Fe-DMY downregulating Poldip2-Nox4-H2O2 pathway and alleviating diabetic retinopathy. Journal of Pharmaceutical Analysis 13:11, pages 1326-1345.
Crossref
Orsolya Balázs, Ágnes Dombi, Balázs Z. Zsidó, Csaba Hetényi, Kateřina Valentová, Róbert G. Vida & Miklós Poór. (2023) Inhibition of xanthine oxidase-catalyzed xanthine and 6-mercaptopurine oxidation by luteolin, naringenin, myricetin, ampelopsin and their conjugated metabolites. Biomedicine & Pharmacotherapy 167, pages 115548.
Crossref
Seon Min Oh, Doo-Young Kim, Su-Yeon Lee, Ha Eun Song, In Seon Kim, Woo Duck Seo, Jeong Hoon Lee, Sei-Ryang Oh, Dae Young Lee & Hyung Won Ryu. (2023) Comparisons of phenolic compounds and antioxidant activities during different growth stages in Artemisia gmelinii Weber ex Stechm with UPLC-QTOF/MS based on a metabolomics approach. Industrial Crops and Products 202, pages 116999.
Crossref
Ziyuan Wang, Zhuoran Cao, Zhiying Yue & Zhengfeng Yang. (2023) Research progress of dihydromyricetin in the treatment of diabetes mellitus. Frontiers in Endocrinology 14.
Crossref
Lin Liu, Quan Shen, Yan Wang, Hong Li & Jingshan Zhao. (2023) Dihydromyricetin Alleviates Nonalcoholic Fatty Liver Disease and Its Associated Metabolic Syndrome by Inhibiting Endoplasmic Reticulum Stress in LDLR−/− Mice Fed with a High-Fat and High-Fructose Diet. Journal of Clinical Pharmacy and Therapeutics 2023, pages 1-12.
Crossref
Dongjin Pan, Zhenzhou Tang, Zhongbao Zhang & Qing X. Li. (2022) Action Mechanisms and Pharmacokinetics of Dihydromyricetin against Obesity. ACS Food Science & Technology 3:4, pages 539-545.
Crossref
H Nie, T Ji, Y Fu, D Chen, Z Tang & C Zhang. (2022) Molecular mechanisms and promising role of dihydromyricetin in cardiovascular diseases. Physiological Research 71:6, pages 749-762.
Crossref
Luting Wu, Min Zhou, Yingquan Xie, Hedong Lang, Tianyou Li, Long Yi, Qianyong Zhang & Mantian Mi. (2022) Dihydromyricetin Enhances Exercise-Induced GLP-1 Elevation through Stimulating cAMP and Inhibiting DPP-4. Nutrients 14:21, pages 4583.
Crossref
Rongxin Cai, Xican Li, Chunhou Li, Jiayi Zhu, Jingyuan Zeng, Jianwu Li, Boxu Tang, Zheng Li, Shuqin Liu & Yan Yan. (2022) Standards-Based UPLC-Q-Exactive Orbitrap MS Systematically Identifies 36 Bioactive Compounds in Ampelopsis grossedentata (Vine Tea). Separations 9:11, pages 329.
Crossref
Eman M. Awad, Al-Shaimaa F. Ahmed, Mahmoud El-Daly, Ali H. Amin, Nashwa F.G. El-Tahawy, AlShimaa Wagdy, Morley D. Hollenberg & Ashraf Taye. (2022) Dihydromyricetin protects against high glucose-induced endothelial dysfunction: Role of HIF-1α/ROR2/NF-κB. Biomedicine & Pharmacotherapy 153, pages 113308.
Crossref
Xi Zhou, Long Yi, Hedong Lang, Jun Zhang, Qianyong Zhang, Li Yu, Jundong Zhu & Mantian Mi. (2022) Dihydromyricetin-Encapsulated Liposomes Inhibit Exhaustive Exercise-Induced Liver Inflammation by Orchestrating M1/M2 Macrophage Polarization. Frontiers in Pharmacology 13.
Crossref
Yirong Wang, Junmin Wang, Hongjiao Xiang, Peilun Ding, Tao Wu & Guang Ji. (2022) Recent update on application of dihydromyricetin in metabolic related diseases. Biomedicine & Pharmacotherapy 148, pages 112771.
Crossref
Xiao-Ya Qin, Xu-Dong Hou, Guang-Hao Zhu, Yuan Xiong, Yun-Qing Song, Liang Zhu, Dong-Fang Zhao, Shou-Ning Jia, Jie Hou, Hui Tang & Guang-Bo Ge. (2022) Discovery and Characterization of the Naturally Occurring Inhibitors Against Human Pancreatic Lipase in Ampelopsis grossedentata. Frontiers in Nutrition 9.
Crossref
Xixin Zhou, Ying Song, Chaoxi Zeng, Haowei Zhang, Chenghao Lv, Meng Shi & Si Qin. (2022) Molecular Mechanism Underlying the Regulatory Effect of Vine Tea on Metabolic Syndrome by Targeting Redox Balance and Gut Microbiota. Frontiers in Nutrition 9.
Crossref
Yang Sun, Shasha Liu, Songwei Yang, Chen Chen, Yantao Yang, Meiyu Lin, Chao Liu, Wenmao Wang, Xudong Zhou, Qidi Ai, Wei Wang & Naihong Chen. (2022) Mechanism of Dihydromyricetin on Inflammatory Diseases. Frontiers in Pharmacology 12.
Crossref
Haolin Zhang, Giovanni Caprioli, Hidayat Hussain, Nguyen Phan Khoi Le, Mohamed A. Farag & Jianbo Xiao. (2021) A multifaceted review on dihydromyricetin resources, extraction, bioavailability, biotransformation, bioactivities, and food applications with future perspectives to maximize its value. eFood 2:4, pages 164-184.
Crossref
Eileen Carry, Dushyant Kshatriya, Joshua Silva, Daryl L. Davies, Bo Yuan, Qingli Wu, Harna Patel, Elizabeth R. Park, John Gilleran, Lihong Hao, Jacques Roberge, Nicholas T. Bello & James E. Simon. (2021) Identification of Dihydromyricetin and Metabolites in Serum and Brain Associated with Acute Anti-Ethanol Intoxicating Effects in Mice. International Journal of Molecular Sciences 22:14, pages 7460.
Crossref
Jing Ye, Sha Bao, Shiying Zhao, Yujing Zhu, Qiao Ren, Rui Li, Xiaohong Xu & Quan Zhang. (2021) Self-Assembled Micelles Improve the Oral Bioavailability of Dihydromyricetin and Anti-Acute Alcoholism Activity. AAPS PharmSciTech 22:3.
Crossref
Hao Liu, Chenyun Gan, Houyin Shi, Kunyan Qu, Liuyang Jing, Muhe Lu, Benyu Su, Huayang Yu, Hang Yuan, Jingjing Chen, Ruirui Zhang & Weiling Zeng. (2021) Gastric floating pill enhances the bioavailability and drug efficacy of dihydromyricetin in vivo. Journal of Drug Delivery Science and Technology 61, pages 102279.
Crossref
Hai-yun Zhou, Shuang-qi Gao, Yu-sheng Gong, Tong Lin, Shuai Tong, Wei Xiong, Chun-yang Shi, Wen-qing Wang & Jian-guo Fang. (2020) Anti-HSV-1 effect of dihydromyricetin from Ampelopsis grossedentata via the TLR9-dependent anti-inflammatory pathway. Journal of Global Antimicrobial Resistance 23, pages 370-376.
Crossref
Lei Chen, Xiujun Lin, Maojun Yao & Hui Teng. (2020) Self-nanoemulsions loaded with dihydromyricetin: Insights to their formulation stability. Food Hydrocolloids 108, pages 105888.
Crossref
Alexandra Bujor, Anca Miron, Simon Vlad Luca, Krystyna Skalicka-Wozniak, Mihaela Silion, Adriana Trifan, Corine Girard, Céline Demougeot & Perle Totoson. (2020) Vasorelaxant effects of Crataegus pentagyna: Links with arginase inhibition and phenolic profile. Journal of Ethnopharmacology 252, pages 112559.
Crossref
Jing Li, Huiling Wang, Jian Li, Yonggang Liu & Hong Ding. (2020) LC-MS analysis of Myrica rubra extract and its hypotensive effects via the inhibition of GLUT 1 and activation of the NO/Akt/eNOS signaling pathway . RSC Advances 10:9, pages 5371-5384.
Crossref
Hilda Martínez-Coria, Martha X. Mendoza-Rojas, Isabel Arrieta-Cruz & Héctor E. López-Valdés. (2019) Preclinical Research of Dihydromyricetin for Brain Aging and Neurodegenerative Diseases. Frontiers in Pharmacology 10.
Crossref
Hao Liu, Wenmei Zhao, Qi Hu, Ling Zhao, Yumeng Wei, Chao Pi, Yuhan Yang, Xuerong Yang, Hang Yuan, Yuhan Zhang, Kunyan Qu, Xinyu Shi, Yao Huang & Houyin Shi. (2019) Gastric floating sustained-release tablet for dihydromyricetin: Development, characterization, and pharmacokinetics study. Saudi Pharmaceutical Journal 27:7, pages 1000-1008.
Crossref
Om Prakash, Revathy Baskaran & V.B. Kudachikar. (2019) Characterization, quantification of free, esterified and bound phenolics in Kainth (Pyrus pashia Buch.-Ham. Ex D.Don) fruit pulp by UPLC-ESI-HRMS/MS and evaluation of their antioxidant activity. Food Chemistry 299, pages 125114.
Crossref
Xinyuan Zhao, Chunyang Shi, Xiya Zhou, Tong Lin, Yusheng Gong, Mingxing Yin, Li Fan, Wenqing Wang & Jianguo Fang. (2019) Preparation of a nanoscale dihydromyricetin-phospholipid complex to improve the bioavailability: in vitro and in vivo evaluations. European Journal of Pharmaceutical Sciences 138, pages 104994.
Crossref
Dan Liu, Yiqin Mao, Lijun Ding & Xin-An Zeng. (2019) Dihydromyricetin: A review on identification and quantification methods, biological activities, chemical stability, metabolism and approaches to enhance its bioavailability. Trends in Food Science & Technology 91, pages 586-597.
Crossref
Jun Fan, Heng Zhang, Mengjiao Yi, Feng Liu & Zhongni Wang. (2019) Temperature induced phase transformation and in vitro release kinetic study of dihydromyricetin-encapsulated lyotropic liquid crystal. Journal of Molecular Liquids 274, pages 690-698.
Crossref
Dong Xiang, Li Fan, Xiao‐long Hou, Wei Xiong, Chun‐yang Shi, Wen‐qing Wang & Jian‐guo Fang. (2018) Uptake and Transport Mechanism of Dihydromyricetin Across Human Intestinal Caco‐2 Cells. Journal of Food Science 83:7, pages 1941-1947.
Crossref
Li Fan, Qing Tong, Weiwei Dong, Guangjie Yang, Xiaolong Hou, Wei Xiong, Chunyang Shi, Jianguo Fang & Wenqing Wang. (2017) Tissue Distribution, Excretion, and Metabolic Profile of Dihydromyricetin, a Flavonoid from Vine Tea ( Ampelopsis grossedentata ) after Oral Administration in Rats . Journal of Agricultural and Food Chemistry 65:23, pages 4597-4604.
Crossref
Hongliang Li, Qisheng Li, Zhaowen Liu, Kai Yang, Zhixi Chen, Qilai Cheng & Longhuo Wu. (2017) The Versatile Effects of Dihydromyricetin in Health. Evidence-Based Complementary and Alternative Medicine 2017, pages 1-10.
Crossref