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Research Article

The novel role of β-aescin in attenuating CCl₄-induced hepatotoxicity in rats

Harsimran SinghDepartment of Research, Innovations & Consultancy, IKG Punjab Technical University, Kapurthala, Punjab, India; ;Sri Sai College of Pharmacy, Badhani, Pathankot, Punjab, India;

Shabir SidhuDepartment of Life Sciences, Punjab Institute of technology, IKG Punjab Technical University, Kapurthala, Punjab, India;

Kanwaljit ChopraPharmacology Research Laboratory, University Institute of Pharmaceutical Sciences, UGC Centre of Advanced Study, Punjab University, Chandigarh, India

M. U. KhanSri Sai College of Pharmacy, Badhani, Pathankot, Punjab, India; Correspondence[email protected]

Pages 749-757 | Received 11 Oct 2015, Accepted 17 Dec 2016, Published online: 09 Jan 2017

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https://doi.org/10.1080/13880209.2016.1275023
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İsmail Küçükkurt, Erten Akbel, Sinan İnce, Damla Arslan Acaröz, Hasan Hüseyin Demirel & Fahriye Kan. (2022) Potential protective effect of escin from Aesculus hippocastanum extract against cyclophosphamide-induced oxidative stress on rat tissues . Toxicology Research 11:5, pages 812-818.
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Stefano Quarta, Giuseppe Santarpino, Maria Annunziata Carluccio, Nadia Calabriso, Egeria Scoditti, Luisa Siculella, Fabrizio Damiano, Michele Maffia, Tiziano Verri, Raffaele De Caterina & Marika Massaro. (2022) Analysis of the Anti-Inflammatory and Anti-Osteoarthritic Potential of Flonat Fast®, a Combination of Harpagophytum Procumbens DC. ex Meisn., Boswellia Serrata Roxb., Curcuma longa L., Bromelain and Escin (Aesculus hippocastanum), Evaluated in In Vitro Models of Inflammation Relevant to Osteoarthritis. Pharmaceuticals 15:10, pages 1263.
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Sefa Gözcü. 2022. Novel Drug Targets With Traditional Herbal Medicines. Novel Drug Targets With Traditional Herbal Medicines 23 36 .

Fares E.M. Ali, Salwa F. Ahmed, Amira H. Eltrawy, Reda S. Yousef, Howaida S. Ali, Amany R. Mahmoud & Tarek H. Abd-Elhamid. (2021) Pretreatment with Coenzyme Q10 Combined with Aescin Protects against Sepsis-Induced Acute Lung Injury. Cells Tissues Organs 210:3, pages 195-217.
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Sara Mahmmoud EL-Dakhly, Abeer Abdallah Ali Salama, Soha Osama Mahmoud Hassanin, Noha Nazeeh Yassen, Alaaeldin Ahmed Hamza & Amr Amin. (2020) Aescin and diosmin each alone or in low dose- combination ameliorate liver damage induced by carbon tetrachloride in rats. BMC Research Notes 13:1.
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Yunqi Yang, Linlin Wang, Man Yuan, Qi Yu & Fenghua Fu. (2020) Anti-Inflammatory and Gastroprotective Effects of Escin. Natural Product Communications 15:12, pages 1934578X2098211.
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Sahar Idris, Anuradha Mishra & Mohd Khushtar. (2020) Phytochemical, ethanomedicinal and pharmacological applications of escin from Aesculus hippocastanum L . towards future medicine . Journal of Basic and Clinical Physiology and Pharmacology 31:5.
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Huda J. Waheed, Saad B. Nashtar, Ali I. Al-Gareeb & Hayder M. Al-Kuraishy. (2019) Neurobehavioral Effects of β-Escin. Current Psychopharmacology 8:1, pages 79-86.
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Yilmaz Bilgic, Sami Akbulut, Zeynep Aksungur, Mehmet Erdemli, Onural Ozhan, Hakan Parlakpinar, Nigar Vardi & Yusuf Turkoz. (2018) Protective effect of dexpanthenol against cisplatin‑induced hepatotoxicity. Experimental and Therapeutic Medicine.
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Abdullah Aslan, Ozlem Gok, Orhan Erman & Tuncay Kuloglu. (2018) Ellagic acid impedes carbontetrachloride-induced liver damage in rats through suppression of NF-kB, Bcl-2 and regulating Nrf-2 and caspase pathway. Biomedicine & Pharmacotherapy 105, pages 662-669.
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Hossein Maghsoudi, Jamal Hallajzadeh & Mozhghan Rezaeipour. (2018) Evaluation of the effect of polyphenol of escin compared with ibuprofen and dexamethasone in synoviocyte model for osteoarthritis: an in vitro study. Clinical Rheumatology 37:9, pages 2471-2478.
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The novel role of β-aescin in attenuating CCl₄-induced hepatotoxicity in rats

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The novel role of β-aescin in attenuating CCl4-induced hepatotoxicity in rats

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The novel role of β-aescin in attenuating CCl₄-induced hepatotoxicity in rats