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Pharmaceutical Biology Volume 55, 2017 - Issue 1
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Research Article

Modulation of some markers of erectile dysfunction and malonaldehyde levels in isolated rat penile tissue with unripe and ripe plantain peels: identification of the constituents of the plants using HPLC

Ganiyu Oboha Department of Biochemistry, Federal University of Technology, Akure, Nigeria; Correspondence[email protected]
,
Adedayo Oluwaseun Ademiluyia Department of Biochemistry, Federal University of Technology, Akure, Nigeria; ORCID Iconhttps://orcid.org/0000-0001-8325-1304
ORCID Icon,
Sunday Idowu Oyeleyea Department of Biochemistry, Federal University of Technology, Akure, Nigeria; ;b Department of Biomedical Technology, Federal University of Technology, Akure, Nigeria; ORCID Iconhttps://orcid.org/0000-0003-3935-2313
ORCID Icon,
Tosin Abiola Olasehindec Division of Nutrition and Toxicology, Department of Food Technology, Federal Institute of Industrial Research Oshodi, Lagos, Nigeria;
&
Aline Augusti Boligond Phytochemical Research Laboratory, Department of Industrial Pharmacy, Federal University of Santa Maria, Santa Maria, BrazilORCID Iconhttps://orcid.org/0000-0001-5434-5037
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Pages 1920-1926 | Received 09 Aug 2016, Accepted 04 Jun 2017, Published online: 27 Jun 2017

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Seun A. Akomolafe, Sunday I. Oyeleye, Tosin A. Olasehinde & Ganiyu Oboh. (2018) Phenolic characterization, antioxidant activities, and inhibitory effects of Physalis angulata and Newbouldia laevis on enzymes linked to erectile dysfunction. International Journal of Food Properties 21:1, pages 645-654.
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Sunday I. Oyeleye, Adeniyi A. Adebayo, Opeyemi B. Ogunsuyi, Felix A. Dada & Ganiyu Oboh. (2017) Phenolic profile and Enzyme Inhibitory activities of Almond (Terminalia catappa) leaf and Stem bark. International Journal of Food Properties 20:sup3, pages S2810-S2821.
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Patience N. Ogbu, Ademola C. Famurewa, Chidinma K. Ugbor, Ikechukwu M. Ogbu, Chinyere Aloke, Nwogo A. Obasi, Tawakalitu A. Aliu & Arunaksharan Narayanankutty. (2024) HPLC phytochemical profiling, antioxidant activity and in vitro evaluation of inhibitory effects of Terminalia catappa stem bark extract on enzymes linked to diabetes, hypertensive vasoconstriction and erectile dysfunction. Pharmacological Research - Natural Products 4, pages 100064.
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Hayat Ouassou, Nour Elhouda Daoudi, Saliha Bouknana, Rhizlan Abdnim & Mohamed Bnouham. (2024) A Review of Antidiabetic Medicinal Plants as a Novel Source of Phosphodiesterase Inhibitors: Future Perspective of New Challenges Against Diabetes Mellitus. Medicinal Chemistry 20:5, pages 467-486.
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Olalekan Bukunmi Ogunro & Musa Toyin Yakubu. (2022) Fadogia agrestis (Schweinf. Ex Hiern) Stem Extract Restores Selected Biomolecules of Erectile Dysfunction in the Testicular and Penile Tissues of Paroxetine-Treated Wistar Rats. Reproductive Sciences 30:2, pages 690-700.
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Vaishali M. Patil, Neeraj Masand, Vertika Gautam, Shikha Kaushik & Dee Wu. 2023. Deciphering Drug Targets for Alzheimer’s Disease. Deciphering Drug Targets for Alzheimer’s Disease 285 319 .
Sunday Idowu Oyeleye, Tosin Abiola Olasehinde, Ibrahim Pelumi Odumosu & Ganiyu Oboh. (2022) Plantain peels restore sexual performance, hormonal imbalance, and modulate nitric oxide production and key enzymes of penile function in paroxetine‐sexually impaired male rats. Journal of Food Biochemistry 46:11.
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Ayokunle O. Ademosun, Ganiyu Oboh, Adeniyi A. Adebayo, Tosin A. Olasehinde & Olamide W. Fasakin. (2022) Grapefruit peel extract mitigates paroxetine‐induced erectile dysfunction in rats through stimulation of erectile response, antioxidant status, and inhibition of key enzymes related with impaired penile erection. Journal of Food Biochemistry 46:11.
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Seun F. Akomolafe, Sunday I. Oyeleye & Ganiyu Oboh. (2022) Effect of cashew ( Anacardium occidentale L.) nut‐supplemented diet on steroidogenic enzymes, hormonal and oxidative imbalances, and sperm parameters in cisplatin‐induced reproductive toxicity in male rats . Journal of Food Biochemistry 46:7.
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Ayodeji A. Olabiyi & Kayode Ajayi. (2022) Diet, herbs and erectile function: A good friendship!. Andrologia 54:6.
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Olamide W. Fasakin, Ganiyu Oboh & Ayokunle Olubode Ademosun. (2022) Alkaloids-rich extracts from Cannabis sativa, Datura stramonium, and Nicotiana tabacum modulate sexual behavior and key enzymes relevant to sexual function in rats. Comparative Clinical Pathology 31:3, pages 397-407.
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Jun Chen, Fei Zhu, Meiling Pan, Qing Liu, Lin Chen & Yi Tao. (2022) An emerging strategy for tracing the anti‐erectile dysfunction components of raw and salt‐processed semens of Astragali Complanati by combinatory liquid chromatography–mass spectrometry‐based quantitative analysis, efficacy assessment on impotent rats, and partial least squares regression . Journal of Separation Science 45:11, pages 1952-1959.
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Stephen A. Adefegha, Felix A. Dada, Sunday I. Oyeleye & Ganiyu Oboh. (2022) Effect of oral berberine administration on the renal profiles of adenosine deaminase, arginase, and nitric oxide in streptozotocin-induced diabetic nephropathy of rats. Comparative Clinical Pathology 31:2, pages 255-263.
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Sunday Idowu Oyeleye, Oluwasegun E. Ajayi, Ayokunle O. Ademosun & Ganiyu Oboh. (2021) GC characterization and erectogenic enzyme inhibitory effect of essential oils from tangerine and lemon peels: A comparative study. Flavour and Fragrance Journal 37:1, pages 33-42.
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Chinyere S. Dike, Chinna N. Orish, Chukwuemeka R. Nwokocha, Francis D. Sikoki, Bolaji B. Babatunde, Chiara Frazzoli & Orish E. Orisakwe. (2021) Phytowaste as nutraceuticals in boosting public health. Clinical Phytoscience 7:1.
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Giovanni Ribaudo, Maurizio Memo & Alessandra Gianoncelli. (2021) Multi-target Natural and Nature-Inspired Compounds against Neurodegeneration: A Focus on Dual Cholinesterase and Phosphodiesterase Inhibitors. Applied Sciences 11:11, pages 5044.
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A. Anand Ganapathy, V.M. Hari Priya & Alaganandam Kumaran. (2021) Medicinal plants as a potential source of Phosphodiesterase-5 inhibitors: A review. Journal of Ethnopharmacology 267, pages 113536.
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Nelisiwe Prenate Masuku, Jeremiah Oshiomame Unuofin & Sogolo Lucky Lebelo. (2020) Promising role of medicinal plants in the regulation and management of male erectile dysfunction. Biomedicine & Pharmacotherapy 130, pages 110555.
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Shian-Ren Lin, Shiuan-Yea Lin, Ching-Cheng Chen, Yaw-Syan Fu & Ching-Feng Weng. (2019) Exploring a New Natural Treating Agent for Primary Hypertension: Recent Findings and Forthcoming Perspectives. Journal of Clinical Medicine 8:11, pages 2003.
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Sunday Idowu Oyeleye, Stephen Adeniyi Adefegha, Felix Abayomi Dada, Bathlomew Maduka Okeke & Ganiyu Oboh. (2019) Effect of p ‐coumaric acid on the erectogenic enzyme activities and non‐protein thiol level in the penile tissue of normal and doxorubicin‐induced oxidative stress male rat . Andrologia 51:6, pages e13281.
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Adedayo O. Ademiluyi, Sunday I. Oyeleye, Opeyemi B. Ogunsuyi & Ganiyu Oboh. (2019) Phenolic analysis and erectogenic function of African Walnut ( Tetracarpidium conophorum ) seeds: The impact of the seed shell on biological activity . Journal of Food Biochemistry 43:6, pages e12815.
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G. Oboh, S.I. Oyeleye & A.O. Ademiluyi. (2019) The food and medicinal values of indigenous leafy vegetables. Acta Horticulturae:1238, pages 137-156.
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Basiru Olaitan Ajiboye, Maureen Chidima Akalabu, Oluwafemi Adeleke Ojo, Olakunle Bamikole Afolabi, Mary Abiola Okesola, Israel Olayide & Babatunji Emmanuel Oyinloye. (2018) Inhibitory effect of ethyl acetate fraction of Solanum macrocarpon L. leaves on cholinergic, monoaminergic, and purinergic enzyme activities . Journal of Food Biochemistry 42:6, pages e12643.
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Stephen Adeniyi Adefegha, Bathlomew Maduka Okeke & Ganiyu Oboh. (2018) Comparative study on the interaction of eugenol, Butylated hydroxylanisole, and Butylated hydroxyl toluene with some crucial enzymes linked to erectile dysfunction. Comparative Clinical Pathology 27:6, pages 1699-1706.
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Adedayo O. Ademiluyi. (2018) Local condiments from fermented tropical legume seeds modulate activities of critical enzymes relevant to cardiovascular diseases and endothelial function. Food Science & Nutrition 6:3, pages 602-608.
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Veronica O. Odubanjo, Tosin A. Olasehinde, Sunday I. Oyeleye, Ganiyu Oboh & Aline A. Boligon. (2018) Seed extracts from Myristica fragrans (Nutmeg) and Moringa oleifera (Drumstick tree) inhibits enzymes relevant to erectile dysfunction and metal-induced oxidative damage in rats' penile tissues . Journal of Food Biochemistry 42:1, pages e12452.
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