12,837
Views
194
CrossRef citations to date
0
Altmetric
Review Article

A comprehensive review on phytochemistry, pharmacology, and flavonoid biosynthesis of Scutellaria baicalensis

, , , , &
Pages 465-484 | Received 18 Apr 2018, Accepted 20 Jun 2018, Published online: 05 Dec 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Xinyi Yang, Sihao Zheng, Xiaotong Wang, Jing Wang, Syed Basit Ali shah, Yu Wang, Ranran Gao & Zhichao Xu. (2022) Advances in pharmacology, biosynthesis, and metabolic engineering of Scutellaria-specialized metabolites. Critical Reviews in Biotechnology 0:0, pages 1-17.
Read now
Yuanyu Shan, Xiaoying Pei, Shunyuan Yong, Jingling Li, Qiulin Qin, Siyuan Zeng & Jie Yu. (2021) Analysis of the complete chloroplast genomes of Scutellaria tsinyunensis and Scutellaria tuberifera (Lamiaceae). Mitochondrial DNA Part B 6:9, pages 2672-2680.
Read now
Hongbo Liu, Fei Ye, Qi Sun, Hao Liang, Chunmei Li, Siyang Li, Roujian Lu, Baoying Huang, Wenjie Tan & Luhua Lai. (2021) Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitro. Journal of Enzyme Inhibition and Medicinal Chemistry 36:1, pages 497-503.
Read now

Articles from other publishers (189)

Dilip Kumar Chanchal, Kuldeep Singh, Bharat Bhushan, Jitendra Singh Chaudhary, Shivendra Kumar, Ajit Kumar Varma, Neha Agnihotri & Akash Garg. (2023) An updated review of Chinese skullcap (Scutellaria baicalensis): Emphasis on phytochemical constituents and pharmacological attributes. Pharmacological Research - Modern Chinese Medicine 9, pages 100326.
Crossref
Li Gao, Jin-xia Zhao, Xue-mei Qin & Jing Zhao. (2023) The ethanol extract of Scutellaria baicalensis Georgi attenuates complete Freund's adjuvant (CFA)-induced inflammatory pain by suppression of P2X3 receptor. Journal of Ethnopharmacology 317, pages 116762.
Crossref
A. I. Solov’eva, A. Y. Stepanova, T. V. Ivanova, A. S. Voronkov & Yu. M. Panov. (2023) Dose-dependent effect of H2O2 on hairy roots of Scutellaria baicalensis: growth, composition of fatty acids, and flavones. Plant Cell, Tissue and Organ Culture (PCTOC) 155:3, pages 893-905.
Crossref
Yaxue Han, Zi Yang, Shan Fang, Mengqing Zhang, Zhijun Xie, Yongsheng Fan & Ting Zhao. (2022) Data‐mining‐based of ancient traditional Chinese medicine records from 475 BC to 1949 to potentially treat COVID‐19 . The Anatomical Record 306:12, pages 2984-2996.
Crossref
Agata Wilczańska, Barbara Sparzak-Stefanowska, Adam Kokotkiewicz, Anna Jesionek, Aleksandra Królicka, Maria Łuczkiewicz & Mirosława Krauze-Baranowska. (2023) Biotechnological strategies for controlled accumulation of flavones in hairy root culture of Scutellaria lateriflora L.. Scientific Reports 13:1.
Crossref
Haruna Nagayoshi, Norie Murayama, Vitchan Kim, Donghak Kim, Shigeo Takenaka, Hiroshi Yamazaki, F. Peter Guengerich & Tsutomu Shimada. (2023) Oxidation of Naringenin, Apigenin, and Genistein by Human Family 1 Cytochrome P450 Enzymes and Comparison of Interaction of Apigenin with Human P450 1B1.1 and Scutellaria P450 82D.1. Chemical Research in Toxicology 36:11, pages 1778-1788.
Crossref
Shuyi Qi, Beixuan He, Haotian Wang, Yaqian Duan, Lunuan Wang, Yue Gao & Meili Guo. (2023) A Muti-Substrate Flavonol O-glucosyltransferases from Safflower. Molecules 28:22, pages 7613.
Crossref
Yu Feng, Peng Zhu, Dong Wu & Wenbin Deng. (2023) A Network Pharmacology Prediction and Molecular Docking-Based Strategy to Explore the Potential Pharmacological Mechanism of Astragalus membranaceus for Glioma. International Journal of Molecular Sciences 24:22, pages 16306.
Crossref
Xiaorong Zhang, Seung-Bum Yang, Lin Cheng, Koo Ho & Min-Sun Kim. (2023) Botanical Mixture Containing Nitric Oxide Metabolite Enhances Neural Plasticity to Improve Cognitive Impairment in a Vascular Dementia Rat Model. Nutrients 15:20, pages 4381.
Crossref
Shuai Yan, Yahui Wang, Yunhui Gu, Mingyue Zhou, Lianlin Su, Tianpeng Yin, Wei Zhang & Yinzi Yue. (2023) Baicalin suppresses colorectal cancer cell proliferation, potentially via ARRDC4: Bioinformatics and experimental analysis. Arabian Journal of Chemistry 16:10, pages 105141.
Crossref
Qichao Hu, Shuyu Hou, Baoyi Xiong, Yueqiang Wen, Jundong Wang, Jinhao Zeng, Xiao Ma & Fang Wang. (2023) Therapeutic Effects of Baicalin on Diseases Related to Gut–Brain Axis Dysfunctions. Molecules 28:18, pages 6501.
Crossref
Chunni Chen, Linlin Yang, Mengru Li, Li Gao, Xuemei Qin, Guanhua Du & Yuzhi Zhou. (2023) Study on the targeted regulation of Scutellaria baicalensis leaf on glutamine–glutamate metabolism and glutathione synthesis in the liver of d -gal ageing rats . Journal of Pharmacy and Pharmacology 75:9, pages 1212-1224.
Crossref
Zongze He, Chongying Li, Xia Xiao, Hongwei Liu, Man Wang, Xiang Zhou & Jian He. (2023) Effects of extracts of Scutellaria baicalensis and Lonicerae Flos on reproductive performance, milk quality and serum indexes in sows and growth performance in suckling piglets. Livestock Science 275, pages 105295.
Crossref
Yaqian Zhou, Qianqian Xue, Miaomiao Wang, Liyan Mu, Danni Chen, Qiao Liu, Xun Liu, Wu Yin & Fangzhou Yin. (2023) Analysis of quality differences between Scutellaria baicalensis Georgi and Scutellaria rehderiana Diels based on phytochemistry and bioactivity evaluation. Journal of Pharmaceutical and Biomedical Analysis 234, pages 115481.
Crossref
Misaki Watanabe, Tadahiro Yahagi, Rina Kamikura, Hitoshi Kotani, Katsunori Miyake & Keiichi Matsuzaki. (2023) Methoxyflavones isolated from the whole plant of Scutellaria rubropunctata Hayata var. rubropunctata promote osteoblast differentiation in MC3T3-E1 cells. Journal of Natural Medicines 77:4, pages 748-760.
Crossref
Yuqian Kang, Yuxin Li, Tingting Zhang, Peng Wang, Wen Liu, Zhao Zhang, Wengang Yu, Jian Wang, Jian Wang & Yang Zhou. (2023) Integrated metabolome, full‐length sequencing, and transcriptome analyses unveil the molecular mechanisms of color formation of the canary yellow and red bracts of Bougainvillea × buttiana ‘Chitra’ . The Plant Journal.
Crossref
Salihu Mohammed, Isabella Russo & Ileana Ramazzina. (2023) Uncovering the Role of Natural and Synthetic Small Molecules in Counteracting the Burden of α-Synuclein Aggregates and Related Toxicity in Different Models of Parkinson’s Disease. International Journal of Molecular Sciences 24:17, pages 13370.
Crossref
Bui T. Tung, Tran V. Linh, Trinh P. Thao & Nguyen D. Thuan. 2023. Phytochemical Drug Discovery for Central Nervous System Disorders. Phytochemical Drug Discovery for Central Nervous System Disorders 219 250 .
Syamsu Nur, Heri Setiawan, Muhammad Hanafi & Berna Elya. (2023) Phytochemical composition, antioxidant, in vitro and in silico studies of active compounds of Curculigo latifolia extracts as promising elastase inhibitor. Saudi Journal of Biological Sciences 30:8, pages 103716.
Crossref
Xiaojing Li, Yichen Bai, Yanju Bi, Qian Wu & Shiwen Xu. (2023) Baicalin suppressed necroptosis and inflammation against chlorpyrifos toxicity; involving in ER stress and oxidative stress in carp gills. Fish & Shellfish Immunology 139, pages 108883.
Crossref
Qiuju HUANG, Muyang WANG, Min WANG, Yuhui LU, Xiaohua WANG, Xin CHEN, Xin YANG, Hongwei GUO, Rongrong HE & Zhuo LUO. (2023) Scutellaria baicalensis: a promising natural source of antiviral compounds for the treatment of viral diseases. Chinese Journal of Natural Medicines 21:8, pages 563-575.
Crossref
Dali Geng, Rongyu Wang, Ya Zhang, Heng Lu, Hongjing Dong, Wei Liu, Lanping Guo & Xiao Wang. (2023) A 13-LOX participates in the biosynthesis of JAs and is related to the accumulation of baicalein and wogonin in Scutellaria baicalensis. Frontiers in Plant Science 14.
Crossref
Mingrui Yang, Luyao Ma, Rina Su, Rui Guo, Na Zhou, Menghua Liu, Jun Wu, Yi Wang & Yu Hao. (2023) The Extract of Scutellaria baicalensis Attenuates the Pattern Recognition Receptor Pathway Activation Induced by Influenza A Virus in Macrophages. Viruses 15:7, pages 1524.
Crossref
Kuangyang Yang, Qian Xie, Jiaxin Liao, Na Zhao, Jianhui Liang, Ben Liu, Jianhai Chen, Wenxiang Cheng, Xueling Bai, Peng Zhang, Qian Liu, Bing Song, Junyi (Danny) Wang, Fanghao Zheng, Chun Hu, Lichu Liu, Lei Chen & Yan Wang. (2023) Shang-Ke-Huang-Shui and coptisine alleviate osteoarthritis in the knee of monosodium iodoacetate-induced rats through inhibiting CXCR4 signaling. Journal of Ethnopharmacology 311, pages 116476.
Crossref
Yanqing Yao, Haijun Du, Lijun Yang, Xue Li & Hong Cui. (2023) Pharmacodynamic Study of Redujing Oral Liquid on Epstein-Barr Virus (EBV) Associated Infectious Mononucleosis in Children. International Journal of Pharmacology 19:3, pages 381-390.
Crossref
Ying Sun, Jingdan Weng, Xiaolei Chen, Shuyao Ma, Yuxin Zhang, Feng Zhang, Zili Zhang, Feixia Wang, Jiangjuan Shao & Shizhong Zheng. (2023) Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway. Biomedicine & Pharmacotherapy 162, pages 114653.
Crossref
Shuchi Nagar, Saurabh Dey, Aishik Das & Soumya Basu. 2023. Flavonoid Metabolism - Recent Advances and Applications in Crop Breeding. Flavonoid Metabolism - Recent Advances and Applications in Crop Breeding.
Shyamal K. Jash. 2023. Flavonoid Metabolism - Recent Advances and Applications in Crop Breeding. Flavonoid Metabolism - Recent Advances and Applications in Crop Breeding.
Xiaofei Cui, Chang Liu, Penghua Dong, Chao Liu & Yu Bai. (2023) The combination therapy of isomucronulatol 7-O-beta-glucoside (IMG) and CEP-9722 targeting ferroptosis-related biomarkers in non-small cell lung cancer (NSCLC). BMC Pulmonary Medicine 23:1.
Crossref
Yue-E Liang, Hao Zhang, Jiahong Zhu, Hao Wang, Wenli Mei, Bei Jiang, Xupo Ding & Haofu Dai. (2023) Transcriptomic Analysis Reveals the Involvement of Flavonoids Synthesis Genes and Transcription Factors in Dracaena cambodiana Response to Ultraviolet-B Radiation. Forests 14:5, pages 979.
Crossref
Joanna Oracz, Stanisław Kowalski, Dorota Żyżelewicz, Gabriela Kowalska, Dorota Gumul, Kamila Kulbat-Warycha, Justyna Rosicka-Kaczmarek, Anna Brzozowska, Aleksandra Grzegorczyk & Anna Areczuk. (2023) The Influence of Microwave-Assisted Extraction on the Phenolic Compound Profile and Biological Activities of Extracts from Selected Scutellaria Species. Molecules 28:9, pages 3877.
Crossref
Xuejiao Zhao, Xiaolei He, Chuyan Chen, Ying Pei & Yang Wang. (2023) Baicalein suppresses rectal cancer progression through inhibition of cellular glycolysis and intracellular adenosine triphosphate level. Materials Express 13:5, pages 800-805.
Crossref
Lieyan Huang, Lixing Nie, Jing Dong, Lingwen Yao, Shuai Kang, Zhong Dai, Feng Wei & Shuangcheng Ma. (2023) Differential distribution of phytochemicals in Scutellariae Radix and Scutellariae Amoenae Radix using microscopic mass spectrometry imaging. Arabian Journal of Chemistry 16:5, pages 104590.
Crossref
Silvia M. Porras, Rogerio A. Saavedra, Lady J. Sierra, Robert T. González, Jairo R. Martínez & Elena E. Stashenko. (2023) Chemical Characterization and Determination of the Antioxidant Properties of Phenolic Compounds in Three Scutellaria sp. Plants Grown in Colombia. Molecules 28:8, pages 3474.
Crossref
Yuan Jiang, Chenghao Zhu, Shangtao Wang, Fusheng Wang & Zhirong Sun. (2023) Identification of three cultivated varieties of Scutellaria baicalensis using the complete chloroplast genome as a super-barcode. Scientific Reports 13:1.
Crossref
Weijie Jin, Yubao Zhang, Ruoyu Wang, Yajun Wang, Yang Qiu & Xuesi Su. (2023) Small RNA sequencing of Scutellaria baicalensis reveals brassica yellows virus infection and the complementary development of a sensitive and reliable RT-qPCR assay. Crop Protection 166, pages 106186.
Crossref
Cecilia Espíndola. (2023) Some Nanocarrier’s Properties and Chemical Interaction Mechanisms with Flavones. Molecules 28:6, pages 2864.
Crossref
Kajetan Grzelka, Adam Matkowski & Sylwester Ślusarczyk. (2023) Electrostimulation improves plant growth and modulates the flavonoid profile in aeroponic culture of Scutellaria baicalensis Georgi. Frontiers in Plant Science 14.
Crossref
Siqi Sun, Axiang Yu, Ruiyang Cheng, Le Wang, Ting He, Xiao Xu, Ruolan Song, Dongjie Shan, Fang Lv, Xiangjian Zhong, Qingyue Deng, Xianxian Li, Yingyu He, Yuan Zheng, Xueyang Ren, Qing Xia & Gaimei She. (2023) Similarities and differences between Ziqin and Kuqin in anti-inflammatory, analgesic, and antioxidant activities and their core chemical composition based on the zebrafish model and spectrum-effect relationship. Journal of Ethnopharmacology 304, pages 116049.
Crossref
Haeni Seo & Ho-Sueb Song. (2023) Scutellaria baicalensis Extract Alleviates Pain and Inflammation in Animal Models . Journal of Acupuncture Research 40:1, pages 35-43.
Crossref
Zijian Sun, Wei Shen, Weixuan Fang, Huiqiong Zhang, Ziran Chen, Lianghui Xiong & Tianhao An. (2023) The Quality of Scutellaria baicalensis Georgi Is Effectively Affected by Lithology and Soil’s Rare Earth Elements (REEs) Concentration. Applied Sciences 13:5, pages 3086.
Crossref
Xing Liu, Xinhui Peng, Shuai Cen, Cuiting Yang, Zhijie Ma & Xinyuan Shi. (2023) Wogonin induces ferroptosis in pancreatic cancer cells by inhibiting the Nrf2/GPX4 axis. Frontiers in Pharmacology 14.
Crossref
Inga Kwiecień, Aleksandra Łukaszyk, Natalizia Miceli, Maria Fernanda Taviano, Federica Davì, Elżbieta Kędzia & Halina Ekiert. (2023) In Vitro Cultures of Scutellaria brevibracteata subsp. subvelutina as a Source of Bioactive Phenolic Metabolites. Molecules 28:4, pages 1785.
Crossref
Yanqi Jiao, Chengcheng Shi & Yao Sun. (2023) Unraveling the Role of Scutellaria baicalensis for the Treatment of Breast Cancer Using Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation. International Journal of Molecular Sciences 24:4, pages 3594.
Crossref
Ritchu Babbar, Ramanpreet Kaur, Parteek Rana, Sandeep Arora, Tapan Behl, Mohammed Albratty, Asim Najmi, Abdulkarim M. Meraya, Hassan A. Alhazmi & Rajeev K. Singla. (2023) The Current Landscape of Bioactive Molecules against DENV: A Systematic Review. Evidence-Based Complementary and Alternative Medicine 2023, pages 1-17.
Crossref
Yumin Fang, Jie Liu, Minmin Zheng, Sanming Zhu, Tianlin Pei, Mengying Cui, Lijing Chang, Hanwen Xiao, Jun Yang, Cathie Martin & Qing Zhao. (2023) SbMYB3 transcription factor promotes root-specific flavone biosynthesis in Scutellaria baicalensis . Horticulture Research 10:2.
Crossref
Yuzhou Liu, Xiaofei Shen, Mengxiang Sha, Zige Feng & Yue Liu. (2023) Natural bioactive flavonoids as promising agents in alleviating exercise-induced fatigue. Food Bioscience 51, pages 102360.
Crossref
Yi-Teng Xia, Edwin Hok-Chi Cheng, Huai-You Wang, Lynn Hoi-Lam Zhang, Sheng-Ying Lin, Tina Ting-Xia Dong, Ran Duan, Qi-Wei Qin, Wen-Xiong Wang & Karl Wah-Keung Tsim. (2023) The extract from aerial part of Scutellaria baicalensis regulates gut microbiota in rabbit fish: Replacement of antibiotic fighting against pathogenic bacteria. Aquaculture 565, pages 739140.
Crossref
Jung Yoon Jang, Eunok Im & Nam Deuk Kim. (2023) Therapeutic Potential of Bioactive Components from Scutellaria baicalensis Georgi in Inflammatory Bowel Disease and Colorectal Cancer: A Review. International Journal of Molecular Sciences 24:3, pages 1954.
Crossref
Dali Geng, Mei Jiang, Hongjing Dong, Rongyu Wang, Heng Lu, Wei Liu, Lanping Guo, Luqi Huang & Wang Xiao. (2023) MeJA regulates the accumulation of baicalein and other 4’-hydroxyflavones during the hollowed root development in Scutellaria baicalensis. Frontiers in Plant Science 13.
Crossref
Zulikhan Khaditovna Alkhanova, Sabina Lechaevna Abueva, Fariza Ismailovna Kadaeva, Khusein Magamedovich Dadaev, Aza Vahaevna Esilaeva & Ela Balaudinovich Isaev. (2023) The Role of Phytotherapy in the Prevention of The Recurrence of Ischemic Strokes. Archives of Pharmacy Practice 14:3, pages 53-57.
Crossref
Minmin Zheng, Yumin Fang & Qing Zhao. (2023) Comparative analysis of flavones from six commonly used <i>Scutellaria</i> species. Medicinal Plant Biology 2:1, pages 0-0.
Crossref
Akshita Arora, Nitin Sharma & Dipti Kakkar. (2023) Natural polysaccharides for ulcerative colitis: A general overview. Asian Pacific Journal of Tropical Biomedicine 13:5, pages 185.
Crossref
Jilin Wang, Xiaojiao Feng, Ziwei Li, Yiting Liu, Wenzhuo Yang, Tingen Zhang, Pan Guo, Zhidong Liu, Dongli Qi & Jiaxin Pi. (2023) The Flavonoid Components of Scutellaria baicalensis: Biopharmaceutical Properties and their Improvement using Nanoformulation Techniques. Current Topics in Medicinal Chemistry 23:1, pages 17-29.
Crossref
Rishika Tewari, Vivek Kumar & H. K. Sharma. (2023) Thermal and nonthermal processing of an underutilized fruit Emblica officinalis (Amla): a sustainable approach . Sustainable Food Technology.
Crossref
Jing Sun, Bo Zhu, Yixuan Sun, Zhihong Li, Ling Dong & Jianbo Chen. (2023) Fourier transform infrared spectroscopic markers of the scorching degree of Scutellariae Radix related to the variation patterns of flavonoids and carbohydrates. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, pages 122312.
Crossref
Dan-na Fang, Chang-wu Zheng & Ye-ling Ma. (2023) Effectiveness of Scutellaria baicalensis Georgi root in pregnancy-related diseases: A review. Journal of Integrative Medicine 21:1, pages 17-25.
Crossref
Ting-Hsu Chen, May-Jywan Tsai, Chun-Sheng Chang, Linxi Xu, Yaw-Syan Fu & Ching-Feng Weng. (2023) The exploration of phytocompounds theoretically combats SARS-CoV-2 pandemic against virus entry, viral replication and immune evasion. Journal of Infection and Public Health 16:1, pages 42-54.
Crossref
Yao Wang, Li Yang, Rong-rong Xing, Run-qin Wang, Xuan Chen & Shuang Hu. (2023) A switchable deep eutectic solvent for the homogeneous liquid-liquid microextraction of flavonoids from “Scutellariae Radix”. Journal of Chromatography A 1688, pages 463712.
Crossref
Yi Wang, Junsen Cheng, Wei Jiang & Shu Chen. (2022) Metabolomics study of flavonoids in Coreopsis tinctoria of different origins by UPLC–MS/MS . PeerJ 10, pages e14580.
Crossref
Wentao Wang, Suying Hu, Jing Yang, Caijuan Zhang, Tong Zhang, Donghao Wang, Xiaoyan Cao & Zhezhi Wang. (2022) A Novel R2R3-MYB Transcription Factor SbMYB12 Positively Regulates Baicalin Biosynthesis in Scutellaria baicalensis Georgi. International Journal of Molecular Sciences 23:24, pages 15452.
Crossref
Yu-Qing Tan, Fei Lin, Yu-Kun Ding, Shuang Dai, Ying-Xin Liang, Yun-Shu Zhang, Jun Li & Heng-Wen Chen. (2022) Pharmacological properties of total flavonoids in Scutellaria baicalensis for the treatment of cardiovascular diseases. Phytomedicine 107, pages 154458.
Crossref
Zefeng Zhao, Meng Nian, Haifa Qiao, Xiaohang Yang, Shaoping Wu & Xiaohui Zheng. (2022) Review of bioactivity and structure-activity relationship on baicalein (5,6,7-trihydroxyflavone) and wogonin (5,7-dihydroxy-8-methoxyflavone) derivatives: Structural modifications inspired from flavonoids in Scutellaria baicalensis. European Journal of Medicinal Chemistry 243, pages 114733.
Crossref
Liuwei Zhang, Xuemei Zhang & Zongsuo Liang. (2022) Post-Harvest Processing Methods Have Critical Roles in the Contents of Active Ingredients of Scutellaria baicalensis Georgi. Molecules 27:23, pages 8302.
Crossref
Maciej Spiegel, Tiziana Marino, Mario Prejanò & Nino Russo. (2022) Primary and secondary antioxidant properties of scutellarin and scutellarein in water and lipid-like environments: A theoretical investigation. Journal of Molecular Liquids 366, pages 120343.
Crossref
Hsiaoyu Yang, Yuexiang Ming, Weihsin Wang, Yipeng Jin, Zhihui Hao, Gang Liu, Di Zhang & Jiahao Lin. (2022) Anti-inflammatory and anti-pruritic effects of Chi-Huang Solution in a murine model of allergic contact dermatitis. Journal of Ethnopharmacology 298, pages 115543.
Crossref
Na Miao, Cholil Yun, Yutong Shi, Yuan Gao, Shuang Wu, Zhonghua Zhang, Shulan Han, Huimei Wang & Wenjie Wang. (2022) Enhancement of flavonoid synthesis and antioxidant activity in Scutellaria baicalensis aerial parts by UV-A radiation. Industrial Crops and Products 187, pages 115532.
Crossref
Rong Zhou, Hanbing Yang, Ting Lu, Yanxia Zhao & Weifa Zheng. (2022) Ultraviolet radiation promotes the production of hispidin polyphenols by medicinal mushroom Inonotus obliquus. Fungal Biology 126:11-12, pages 775-785.
Crossref
Ya-Qun Zhang, Meng Zhang, Zi-Long Wang, Xue Qiao & Min Ye. (2022) Advances in plant-derived C-glycosides: Phytochemistry, bioactivities, and biotechnological production. Biotechnology Advances 60, pages 108030.
Crossref
Ying-xin Sun, Xi-juan Jiang, Bin Lu, Qing Gao, Ye-fei Chen, Dan-bin Wu, Wen-yun Zeng, Lin Yang, Hu-hu Li & Bin Yu. (2020) Roles of Gut Microbiota in Pathogenesis of Alzheimer’s Disease and Therapeutic Effects of Chinese Medicine. Chinese Journal of Integrative Medicine 28:11, pages 1048-1056.
Crossref
Suying Hu, Donghao Wang, Wentao Wang, Caijuan Zhang, Yunyun Li, Yueyue Wang, Wen Zhou, Junfeng Niu, Shiqiang Wang, Yi Qiang, Xiaoyan Cao & Zhezhi Wang. (2022) Whole genome and transcriptome reveal flavone accumulation in Scutellaria baicalensis roots. Frontiers in Plant Science 13.
Crossref
Jingru Liang, Xuan Huang & Guo Ma. (2022) Antimicrobial activities and mechanisms of extract and components of herbs in East Asia. RSC Advances 12:45, pages 29197-29213.
Crossref
Anastasiya Fedorova, Lyubov Dyshlyuk, Irina Milentyeva, Anna Loseva, Olga Neverova & Mohammed El Amine Khelef. (2022) Geroprotective activity of trans-cinnamic acid isolated from the Baikal skullcap ( Scutellaria baicalensis). Food Processing: Techniques and Technology, pages 582-591.
Crossref
Tianqi Liang, Yanxiang Kong, Lijun Tang, Junbin Huang, Huabin Wang, Xiaoyi Fang, Airun Zhang & Chun Chen. (2022) Network Pharmacology-Based Analysis on the Potential Biological Mechanisms of Yinzhihuang Oral Liquid in Treating Neonatal Hyperbilirubinemia. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-9.
Crossref
Li Wang, Bin Huo, Lingjie Huang, Lianqiang Che, Bin Feng, Yan Lin, Shengyu Xu, De Wu & Zhengfeng Fang. (2022) Dietary supplementation with a mixture of herbal extracts during late gestation and lactation improves performance of sows and nursing piglets through regulation of maternal metabolism and transmission of antibodies. Frontiers in Veterinary Science 9.
Crossref
Elizaveta Faskhutdinova, Andrey Sukhikh, Violeta Le, Varvara Minina, Mohammed El Amine Khelef & Anna Loseva. (2022) Effects of bioactive substances isolated from Siberian medicinal plants on the lifespan of Caenorhabditis elegans. Foods and Raw Materials, pages 340-352.
Crossref
Yiqing Gu, Qi Zheng, Guifang Fan & Runping Liu. (2022) Advances in Anti-Cancer Activities of Flavonoids in Scutellariae radix: Perspectives on Mechanism. International Journal of Molecular Sciences 23:19, pages 11042.
Crossref
Jun Wang, Shanshan Chen, Jizhou Zhang & Jiasi Wu. (2022) Scutellaria baicalensis georgi is a promising candidate for the treatment of autoimmune diseases. Frontiers in Pharmacology 13.
Crossref
Cholil Yun, Zhuowen Zhao, Ilbong Ri, Yuan Gao, Yutong Shi, Na Miao, Lin Gu, Wenjie Wang & Huimei Wang. (2022) How does UV‐B stress affect secondary metabolites of Scutellaria baicalensis in vitro shoots grown at different 6‐benzyl aminopurine concentrations? . Physiologia Plantarum 174:5.
Crossref
Yiyan Songyang, Wen Li, Wenqiang Li, Ji Yang & TianBao Song. (2022) The inhibition of GLUT1-induced glycolysis in macrophage by phloretin participates in the protection during acute lung injury. International Immunopharmacology 110, pages 109049.
Crossref
Huanyu Guan, Pengfei Li, Qian Wang, Fanli Zeng, Jiashuo Wu, Fangqing Zhang, Shanggao Liao & Yue Shi. (2022) Deciphering the chemical constituents of Shengjiang Xiexin decoction by ultrahigh‐performance liquid chromatography‐quadrupole/orbitrap high‐resolution mass spectrometry and the impact of 20 characteristic components on multidrug resistance‐associated protein 2 in the vesicular transport assay. Journal of Separation Science 45:18, pages 3459-3479.
Crossref
Alieh Alipour, Vafa Baradaran Rahimi & Vahid Reza Askari. (2022) Promising influences of gingerols against metabolic syndrome: A mechanistic review. BioFactors 48:5, pages 993-1004.
Crossref
You-wei Zuo, Feng-qiong Yu, Jia-hui Zhang, Chang-ying Xia, Huan Zhang & Hong-ping Deng. (2022) Contrasting Responses of Rhizosphere Fungi of Scutellaria tsinyunensis , an Endangered Plant in Southwestern China . Microbiology Spectrum 10:4.
Crossref
A. A. Shmarova, N. S. Pivovarova & O. N. Abrosimova. (2022) Risk-based Approach in Obtaining and Analysing the Characteristics of Baikal Skullcap Suspension Cultures. Drug development & registration 11:3, pages 47-56.
Crossref
Maryna Lieshchova & Viktor Brygadyrenko. (2022) Effects of Origanum vulgare and Scutellaria baicalensis on the Physiological Activity and Biochemical Parameters of the Blood in Rats on a High-Fat Diet. Scientia Pharmaceutica 90:3, pages 49.
Crossref
Huajing Zhu & Zeli Chen. (2022) Treatment of Comprehensive Wastewater from Chemical and Pharmaceutical Parks by Fly Ash-Coated Iron Electrode Electrocoagulation. Advances in Materials Science and Engineering 2022, pages 1-12.
Crossref
Jie Shen, Pei Li, Yue Wang, Kailing Yang, Yue Li, Hui Yao, Qiang Wang, Peigen Xiao & Chunnian He. (2022) Pharmacophylogenetic study of Scutellaria baicalensis and its substitute medicinal species based on the chloroplast genomics, metabolomics, and active ingredient. Frontiers in Plant Science 13.
Crossref
Misaki Watanabe, Tadahiro Yahagi, Takahiro Shirayama, Katsunori Miyake, Hitoshi Kotani, Takuya Ogawa & Keiichi Matsuzaki. (2022) Effects of a Whole Plant Extract of Scutellaria rubropunctata var. rubropunctata on Bone Metabolism with Estrogen Receptor Activation. Plants 11:16, pages 2075.
Crossref
Blake Costine, Mengzi Zhang, Shweta Chhajed, Brian Pearson, Sixue Chen & Satya Swathi Nadakuduti. (2022) Exploring native Scutellaria species provides insight into differential accumulation of flavones with medicinal properties. Scientific Reports 12:1.
Crossref
Yizhu Wang, Yongyu Cai, Fangtong Li, Meiyu Zhang, Yongxi Wu, Yulin Dai, Fei Zheng, Hao Yue & Bing Bai. (2022) Effects of Scutellaria baicalensis Georgi. on intestinal flora in rats with spleen deficiency and damp-heat. Journal of Pharmaceutical and Biomedical Analysis 217, pages 114831.
Crossref
Ying Wang, Ting Hu, Jingjing Wei, Xiaoying Yin, Zhonghong Gao & Hailing Li. (2022) Inhibitory activities of flavonoids from Scutellaria baicalensis Georgi on amyloid aggregation related to type 2 diabetes and the possible structural requirements for polyphenol in inhibiting the nucleation phase of hIAPP aggregation. International Journal of Biological Macromolecules 215, pages 531-540.
Crossref
Weixin Liu, Suhang Yu, Yi Feng, Runhong Mo, Kaineng Wang, Menglong Fan, Zhengqi Fan, Hengfu Yin, Jiyuan Li & Xinlei Li. (2022) Comparative Transcriptome and Pigment Analyses Reveal Changes in Gene Expression Associated with Flavonol Metabolism in Yellow Camellia. Forests 13:7, pages 1094.
Crossref
Chun-Ting Liu, I-Ling Hung, Chung Y. Hsu, Kai-Chieh Hu, Yung-Hsiang Chen & Ming-Yen Tsai. (2022) Chinese Herbal Medicine Reduces the Risk of Heart Failure in Hypertensive Patients: A Nationwide, Retrospective, Cohort Study. Frontiers in Cardiovascular Medicine 9.
Crossref
Muddaser Shah, Sidra Mubin, Syed Shams ul Hassan, Priti Tagde, Obaid Ullah, Md. Habibur Rahman, Ahmed Al-Harrasi, Najeeb Ur Rehman & Waheed Murad. (2022) Phytochemical Profiling and Bio-Potentiality of Genus Scutellaria: Biomedical Approach. Biomolecules 12:7, pages 936.
Crossref
Na Miao, Cholil Yun, Shulan Han, Yutong Shi, Yuan Gao, Shuang Wu, Zhuowen Zhao, Huimei Wang & Wenjie Wang. (2022) Postharvest UV-A radiation affects flavonoid content, composition, and bioactivity of Scutellaria baicalensis root. Postharvest Biology and Technology 189, pages 111933.
Crossref
Nan Shen, Tongfei Wang, Quan Gan, Sian Liu, Li Wang & Biao Jin. (2022) Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity. Food Chemistry 383, pages 132531.
Crossref
Ruiyang Sun, Ying Zhang, Weiwei Tang & Bin Li. (2022) Submicron 3,4-dihydroxybenzoic acid–TiO 2 composite particles for enhanced MALDI MS imaging of secondary metabolites in the root of differently aged baical skullcap . The Analyst 147:13, pages 3017-3024.
Crossref
Shujun Zhou, Xiaoke Yin, Jun Yuan, Zhitao Liang, Jingzheng Song, Yunxia Li, Cheng Peng, Peter J Hylands, Zhongzhen Zhao & Qihe Xu. (2022) Antifibrotic activities of Scutellariae Radix extracts and flavonoids: Comparative proteomics reveals distinct and shared mechanisms. Phytomedicine 100, pages 154049.
Crossref
Jinfang Xu, Pengkun Cao, Zhiyu Fan, Xujing Luo, Gangqiang Yang, Tingli Qu & Jianping Gao. (2022) Rapid Screening of Lipase Inhibitors in Scutellaria baicalensis by Using Porcine Pancreatic Lipase Immobilized on Magnetic Core–Shell Metal–Organic Frameworks. Molecules 27:11, pages 3475.
Crossref
Haiyan Wang, Yongyong Yan, Haifeng Lan, Nan Wei, Zhichao Zheng, Lihong Wu, Richard T. Jaspers, Gang Wu & Janak L. Pathak. (2022) Notoginsenoside R1 Promotes Migration, Adhesin, Spreading, and Osteogenic Differentiation of Human Adipose Tissue-Derived Mesenchymal Stromal Cells. Molecules 27:11, pages 3403.
Crossref
Vasanti Suvarna, Bhunesh Bore, Chaitanya Bhawar & Rashmi Mallya. (2022) Complexation of phytochemicals with cyclodextrins and their derivatives- an update. Biomedicine & Pharmacotherapy 149, pages 112862.
Crossref
Xia Li, Xiao-feng Wei, Jin Wu, Zhi-qiang Yin, Li-qin Wan, Hou-yun Sun & Yong-long An. (2022) Geochemical characteristics and growth suitability assessment of Scutellaria baicalensis Georgi in the Earth’s critical zone of North China. Journal of Mountain Science 19:5, pages 1245-1262.
Crossref
Zhilan Qian, Jiahui Yu, Xinjie Chen, Yijia Kang, Yanna Ren, Qi Liu, Jian Lu, Qing Zhao & Menghao Cai. (2022) De Novo Production of Plant 4′-Deoxyflavones Baicalein and Oroxylin A from Ethanol in Crabtree-Negative Yeast . ACS Synthetic Biology 11:4, pages 1600-1612.
Crossref
Xiaori Zhan, Zhehao Chen, Rong Chen & Chenjia Shen. (2022) Environmental and Genetic Factors Involved in Plant Protection-Associated Secondary Metabolite Biosynthesis Pathways. Frontiers in Plant Science 13.
Crossref
Tianlin Pei, Mengxiao Yan, Yanbo Huang, Yukun Wei, Cathie Martin & Qing Zhao. (2022) Specific Flavonoids and Their Biosynthetic Pathway in Scutellaria baicalensis. Frontiers in Plant Science 13.
Crossref
Tianlin Pei, Mengxiao Yan, Tian Li, Xiaoqiang Li, Yijia Yin, Mengying Cui, Yumin Fang, Jie Liu, Yu Kong, Ping Xu & Qing Zhao. (2022) Characterization of UDP-glycosyltransferase family members reveals how major flavonoid glycoside accumulates in the roots of Scutellaria baicalensis. BMC Genomics 23:1.
Crossref
Inga Kwiecień, Natalizia Miceli, Manuela D’Arrigo, Andreana Marino & Halina Ekiert. (2022) Antioxidant Potential and Enhancement of Bioactive Metabolite Production in In Vitro Cultures of Scutellaria lateriflora L. by Biotechnological Methods. Molecules 27:3, pages 1140.
Crossref
Siyu Song, Jing Wang, Guanwen Liu, Lu Ding, Yaxin Li, Hongyu Qi, Lai Wei, Jiachao Zhao, Tian Chen, Meiru Zhao, Ziyuan Wang, Yingying Yang, Daqing Zhao, Xiangyan Li & Zeyu Wang. (2022) Protective Effects of the Wenfei Buqi Tongluo Formula on the Inflammation in Idiopathic Pulmonary Fibrosis through Inhibiting the TLR4/MyD88/NF-κB Pathway. BioMed Research International 2022, pages 1-13.
Crossref
Jiali Zhou, Yushuang Luo, Xincong Kang, Fangzhou Bian & Dongbo Liu. (2022) The root extract of Scutellaria baicalensis Georgi promotes β cell function and protects from apoptosis by inducing autophagy. Journal of Ethnopharmacology 284, pages 114790.
Crossref
John K. Triantafillidis, Eleni Triantafyllidi, Michail Sideris, Theodoros Pittaras & Apostolos E. Papalois. (2022) Herbals and Plants in the Treatment of Pancreatic Cancer: A Systematic Review of Experimental and Clinical Studies. Nutrients 14:3, pages 619.
Crossref
Maciej Spiegel, Tiziana Marino, Mario Prejanò & Nino Russo. (2022) On the Scavenging Ability of Scutellarein against the OOH Radical in Water and Lipid-like Environments: A Theoretical Study. Antioxidants 11:2, pages 224.
Crossref
Xiaolei Zheng, Ping Wang, Mengqi Jia, Qing Li, Anna Zhang & Qingbo Zhou. (2022) Baicalin Alleviates Thrombin-Induced Inflammation in Vascular Smooth Muscle Cells. BioMed Research International 2022, pages 1-10.
Crossref
Ding Huang, Ruhong Ming, Shiqiang Xu, Shaochang Yao, Liangbo Li, Rongshao Huang & Yong Tan. (2022) Genome-Wide Identification of R2R3-MYB Transcription Factors: Discovery of a “Dual-Function” Regulator of Gypenoside and Flavonol Biosynthesis in Gynostemma pentaphyllum. Frontiers in Plant Science 12.
Crossref
Tong-Hua Zhang, Jian-Xin Liang, Deng-Lu Long, Min Ma, Li-Guo Chen, Da-Xiang Lu, Xiao-Hua Jiang, Xue-Song Yang & Guang Wang. (2022) Tocolysis effects of traditional Chinese medicine and their effective components. World Journal of Traditional Chinese Medicine 8:2, pages 188.
Crossref
Markandan Birundadevi, Rangasamy Sivashankar & Sivagnanam Mathukumar. (2022) Scutellarein apoptosis mediated by mitochondria in oral squamous cell carcinomas. Biomedical and Biotechnology Research Journal (BBRJ) 6:1, pages 60.
Crossref
Meng‐Ying Cui, An‐Rui Lu, Jian‐Xu Li, Jie Liu, Yu‐Min Fang, Tian‐Lin Pei, Xin Zhong, Yu‐Kun Wei, Yu Kong, Wen‐Qing Qiu, Yong‐Hong Hu, Jun Yang, Xiao‐Ya Chen, Cathie Martin & Qing Zhao. (2021) Two types of O‐methyltransferase are involved in biosynthesis of anticancer methoxylated 4′‐deoxyflavones in Scutellaria baicalensis Georgi . Plant Biotechnology Journal 20:1, pages 129-142.
Crossref
Adam Zwolan, Dorota Pietrzak, Lech Adamczak, Marta Chmiel, Tomasz Florowski, Stanisław Kalisz, Elżbieta Hać‐Szymańczuk, Joanna Bryś & Jan Oszmiański. (2021) Characteristics of water and ethanolic extracts of Scutellaria baicalensis root and their effect on color, lipid oxidation, and microbiological quality of chicken meatballs during refrigerated storage . Journal of Food Processing and Preservation 46:1.
Crossref
Li Xiang, Yue Gao, Shiyu Chen, Jiayi Sun, Jiasi Wu & Xianli Meng. (2022) Therapeutic potential of Scutellaria baicalensis Georgi in lung cancer therapy. Phytomedicine 95, pages 153727.
Crossref
Cholil Yun, Shengfang Wang, Yuan Gao, Zhuowen Zhao, Na Miao, Yutong Shi, Ilbong Ri, Wenjie Wang & Huimei Wang. (2022) Optimization of ultrasound-assisted enzymatic pretreatment for enhanced extraction of baicalein and wogonin from Scutellaria baicalensis roots. Journal of Chromatography B 1188, pages 123077.
Crossref
Vikas Anand Saharan, Surojit Banerjee, Swati Dobhal, Manoj Kumar Sarangi & Anupama Singh. 2022. Computer Aided Pharmaceutics and Drug Delivery. Computer Aided Pharmaceutics and Drug Delivery 439 471 .
Halina Maria Ekiert, Paweł Kubica, Inga Kwiecień, Karolina Jafernik, Marta Klimek-Szczykutowicz & Agnieszka Szopa. 2022. Plant Antioxidants and Health. Plant Antioxidants and Health 267 309 .
О. О. Poronnik. (2021) OBTAINING OF PLANT TISSUE CULTURE Scutellaria baicalensis GEORGI. AND ITS BIOCHEMICAL ANALYSIS. Biotechnologia Acta 14:6, pages 53-58.
Crossref
Muhammad Ishfaq, Zhiyong Wu, Jian Wang, Rui Li, Chunli Chen & Jichang Li. (2021) Baicalin alleviates Mycoplasma gallisepticum-induced oxidative stress and inflammation via modulating NLRP3 inflammasome-autophagy pathway. International Immunopharmacology 101, pages 108250.
Crossref
Yi-Teng Xia, Edwin Hok-Chi Cheng, Ying-Jie Xia, Qi-Yun Wu, Lynn Hoi-Lam Zhang, Sheng-Ying Lin, Tina Ting-Xia Dong, Qi-Wei Qin, Wen-Xiong Wang & Karl Wah-Keung Tsim. (2021) Characterization of a macrophagic-like cell line derived from rabbit fish (Siganus fuscescens): An illustration of anti-inflammatory responses of the herbal extract of Scutellaria baicalensis. Fish and Shellfish Immunology Reports 2, pages 100036.
Crossref
Nova Syafni, Seema Devi, Amy M. Zimmermann-Klemd, Jakob K. Reinhardt, Ombeline Danton, Carsten Gründemann & Matthias Hamburger. (2021) Immunosuppressant flavonoids from Scutellaria baicalensis. Biomedicine & Pharmacotherapy 144, pages 112326.
Crossref
Weixin Liu, Yi Feng, Suhang Yu, Zhengqi Fan, Xinlei Li, Jiyuan Li & Hengfu Yin. (2021) The Flavonoid Biosynthesis Network in Plants. International Journal of Molecular Sciences 22:23, pages 12824.
Crossref
Lin Yang, Hua Luo, Dechao Tan, Siyuan Zhang, Zhangfeng Zhong, Shengpeng Wang, Chi Teng Vong & Yitao Wang. (2021) A recent update on the use of Chinese medicine in the treatment of inflammatory bowel disease. Phytomedicine 92, pages 153709.
Crossref
Yue Xiao, Lulu Zhang, Jinglin Zhu, Yuru Zhang, Ruijie Yang, Jiangna Yan, Ruifei Huang, Chunli Zheng, Wei Xiao, Chao Huang & Yonghua Wang. (2021) Predicting the herbal medicine triggering innate anti-tumor immunity from a system pharmacology perspective. Biomedicine & Pharmacotherapy 143, pages 112105.
Crossref
Chen Cheng & Xuan Yu. (2021) Research Progress in Chinese Herbal Medicines for Treatment of Sepsis: Pharmacological Action, Phytochemistry, and Pharmacokinetics. International Journal of Molecular Sciences 22:20, pages 11078.
Crossref
Natalia Cichon, Angela Dziedzic, Leslaw Gorniak, Elzbieta Miller, Michal Bijak, Michal Starosta & Joanna Saluk-Bijak. (2021) Unusual Bioactive Compounds with Antioxidant Properties in Adjuvant Therapy Supporting Cognition Impairment in Age-Related Neurodegenerative Disorders. International Journal of Molecular Sciences 22:19, pages 10707.
Crossref
Xiao Lang, Zheng Chen, Xingyu Yang, Qi Yan, Manfei Xu, Wei Liu, Qin He, Yue Zhang, Weiwei Cheng & Wenxia Zhao. (2021) Scutellarein induces apoptosis and inhibits proliferation, migration, and invasion in ovarian cancer via inhibition of EZH2/FOXO1 signaling. Journal of Biochemical and Molecular Toxicology 35:10.
Crossref
Na Yao, Jia-Kang He, Ming Pan, Zhao-Feng Hou, Jin-Jun Xu, Yi Yang, Jian-Ping Tao & Si-Yang Huang. (2021) In Vitro Evaluation of Lavandula angustifolia Essential Oil on Anti-Toxoplasma Activity. Frontiers in Cellular and Infection Microbiology 11.
Crossref
Lin Wang, Jianhua Zhang, Guoyong Shan, Junting Liang, Wenwen Jin, Yingyue Li, Fangchu Su, Yanhua Ba, Xifeng Tian, Xiaoyan Sun, Dayong Zhang, Weihua Zhang & Chuan liang Chen. (2021) Establishment of a Lung Cancer Discriminative Model Based on an Optimized Support Vector Machine Algorithm and Study of Key Targets of Wogonin in Lung Cancer. Frontiers in Pharmacology 12.
Crossref
Haiyue Zhao, Lijie Zhao, Fei Wu & Lan Shen. (2021) Clinical research on traditional Chinese medicine treatment for bacterial vaginosis. Phytotherapy Research 35:9, pages 4943-4956.
Crossref
Yi Tu, Quanli Wu, Jiarui He, Jiasheng Xu, Shasha Yu, Qingfei Wang, Yunqi Cheng, Qijun Yang, Shan Xu & Yi Cao. (2021) Exploring the Potential Molecular Mechanism of Scutellaria baicalensis Georgi in the Treatment of Gastric Cancer Based on Network Pharmacological Analysis and Molecular Docking Technology. Frontiers in Pharmacology 12.
Crossref
Ping Li, Qian Wu, Xiaoqiong Li, Bangyan Hu, Wen Wen & Shijun Xu. (2021) Shenqi Yizhi Granule attenuates Aβ1–42 induced cognitive dysfunction via inhibiting JAK2/STAT3 activated astrocyte reactivity. Experimental Gerontology 151, pages 111400.
Crossref
Ze-Hao Ding, Jia-Ming Hong, Wei-Liang Guo, Gui-Hua Li, Zi-Chen Zhao, Yong Zhou, Shi-Feng Wang, Yun Sun, Jian-Long Li, Dong-Dong Zhang & Yong-Can Zhou. (2021) The screen herbal immunopotentiator and research on its effect on the innate immune system and disease resistance of Nile tilapia (Oreochromis niloticus) against Streptococcus agalactiae. Aquaculture 541, pages 736778.
Crossref
Jingling Li, Yicen Xu, Yuanyu Shan, Xiaoying Pei, Shunyuan Yong, Chang Liu & Jie Yu. (2021) Assembly of the complete mitochondrial genome of an endemic plant, Scutellaria tsinyunensis, revealed the existence of two conformations generated by a repeat-mediated recombination. Planta 254:2.
Crossref
Natalia Cichon, Joanna Saluk-Bijak, Elzbieta Miller, Leslaw Gorniak, Justyna Redlicka, Marta Niwald & Michal Bijak. (2021) The Role of Supplementation with Natural Compounds in Post-Stroke Patients. International Journal of Molecular Sciences 22:15, pages 7893.
Crossref
Fanfan Hou, Yang Liu, YaHsin Cheng, Ni Zhang, Wenpeng Yan & Fang Zhang. (2021) Exploring the Mechanism of Scutellaria baicalensis Georgi Efficacy against Oral Squamous Cell Carcinoma Based on Network Pharmacology and Molecular Docking Analysis. Evidence-Based Complementary and Alternative Medicine 2021, pages 1-15.
Crossref
Murat Erdoğan, Rima Konya, Yağmur Özhan, Hande Sipahi, İlker Çinbilgel, Milena Masullo, Sonia Piacente & Hasan Kırmızıbekmez. (2021) Secondary metabolites from Scutellaria brevibracteata subsp. subvelutina and their in vitro anti-inflammatory activities. South African Journal of Botany 139, pages 12-18.
Crossref
Vafa Baradaran Rahimi, Vahid Reza Askari & Hossein Hosseinzadeh. (2021) Promising influences of Scutellaria baicalensis and its two active constituents, baicalin, and baicalein, against metabolic syndrome: A review . Phytotherapy Research 35:7, pages 3558-3574.
Crossref
Akhtar Ali, En Hyung Kim, Jong-Hyun Lee, Kang-Hyun Leem, Shin Seong & Wonnam Kim. (2021) Processed Scutellaria baicalensis Georgi Extract Alleviates LPS-Induced Inflammatory and Oxidative Stress through a Crosstalk between NF-κB and KEAP1/NRF2 Signaling in Macrophage Cells. Applied Sciences 11:13, pages 6055.
Crossref
. (2021) Withdrawn: A data‐mining based analysis of traditional Chinese medicine in diagnosing and treating COVID ‐19 . The Anatomical Record.
Crossref
Yin-Sir Chung, Pervaiz Khalid Ahmed, Iekhsan Othman & Mohd. Farooq Shaikh. (2021) Orthosiphon stamineus Proteins Alleviate Hydrogen Peroxide Stress in SH-SY5Y Cells. Life 11:6, pages 585.
Crossref
Muddaser Shah, Waheed Murad, Najeeb Ur Rehman, Sobia Ahsan Halim, Manzoor Ahmed, Hazir Rehman, Muhammed Zahoor, Sidra Mubin, Ajmal Khan, Mohamed A. Nassan, Gaber El-Saber Batiha & Ahmed Al-Harrasi. (2021) Biomedical Applications of Scutellaria edelbergii Rech. f.: In Vitro and In Vivo Approach. Molecules 26:12, pages 3740.
Crossref
Hanon Lee, Dong Hun Lee, Jang-Hee Oh & Jin Ho Chung. (2021) Skullcapflavone II Suppresses TNF-α/IFN-γ-Induced TARC, MDC, and CTSS Production in HaCaT Cells. International Journal of Molecular Sciences 22:12, pages 6428.
Crossref
Alena Liskova, Marek Samec, Lenka Koklesova, Samson M. Samuel, Kevin Zhai, Raghad Khalid Al-Ishaq, Mariam Abotaleb, Vladimir Nosal, Karol Kajo, Milad Ashrafizadeh, Ali Zarrabi, Aranka Brockmueller, Mehdi Shakibaei, Peter Sabaka, Ioana Mozos, David Ullrich, Robert Prosecky, Giampiero La Rocca, Martin Caprnda, Dietrich Büsselberg, Luis Rodrigo, Peter Kruzliak & Peter Kubatka. (2021) Flavonoids against the SARS-CoV-2 induced inflammatory storm. Biomedicine & Pharmacotherapy 138, pages 111430.
Crossref
Naser A. Alsharairi. (2021) Scutellaria baicalensis and Their Natural Flavone Compounds as Potential Medicinal Drugs for the Treatment of Nicotine-Induced Non-Small-Cell Lung Cancer and Asthma. International Journal of Environmental Research and Public Health 18:10, pages 5243.
Crossref
Jing-Ze Lu, Dan Ye & Bing-Liang Ma. (2021) Constituents, Pharmacokinetics, and Pharmacology of Gegen-Qinlian Decoction. Frontiers in Pharmacology 12.
Crossref
Mao-Wang Ho, Te-Mao Li, Ju-Pi Li, Jian-Shiun Chiou, Mu-Lin Chiu, Chao-Jung Chen, Chi-Fung Cheng, Fuu-Jen Tsai, Yang-Chang Wu, Ting-Hsu Lin, Chiu-Chu Liao, Shao-Mei Huang, Yu-Ning Lin, Chen-Hsing Chou, Wen-Miin Liang & Ying-Ju Lin. (2021) Chinese Herbal Medicine Usage Reduces Overall Mortality in HIV-Infected Patients With Osteoporosis or Fractures. Frontiers in Pharmacology 12.
Crossref
Lingqi Wang, Changyong Cai, Jiajia Liu & Zhijian Tan. (2021) Selective separation of the homologues of baicalin and baicalein from Scutellaria baicalensis Georgi using a recyclable ionic liquid-based liquid-liquid extraction system. Process Biochemistry 103, pages 1-8.
Crossref
Zhonglei Wang & Liyan Yang. (2021) Chinese herbal medicine: Fighting SARS-CoV-2 infection on all fronts. Journal of Ethnopharmacology 270, pages 113869.
Crossref
Zhanpeng Shang, Lulu Xu, Yao Xiao, Wei Du, Rong An, Min Ye & Xue Qiao. (2021) A global profiling strategy using comprehensive two-dimensional liquid chromatography coupled with dual-mass spectrometry platforms: Chemical analysis of a multi-herb Chinese medicine formula as a case study. Journal of Chromatography A 1642, pages 462021.
Crossref
Jianli Xia, Chunming Liu, Huazhou Niu, Wanchao Hou & Sainan Li. (2021) Screening and isolation of potential lipoxidase and superoxide dismutase inhibitors from Scutellaria baicalensis Georgi using high‐speed countercurrent chromatography target‐guided by ultrafiltration‐liquid chromatography‐mass spectrometry . Journal of Separation Science 44:7, pages 1371-1382.
Crossref
Karolina Wojtunik-Kulesza, Kamila Kasprzak-Drozd, Daniel Sajdlowski, Anna Oniszczuk, Wojciech Swiatkowski & Monika Waksmundzka-Hajnos. (2021) Scutellaria baicalensis – a small plant with large pro-health biological activities . Current Issues in Pharmacy and Medical Sciences 34:1, pages 55-59.
Crossref
Minting Chen, Haitao Xiao, Baisen Chen, Zhaoxiang Bian & Hiu Yee Kwan. (2021) The advantages of using Scutellaria baicalensis and its flavonoids for the management of non-viral hepatocellular carcinoma. Journal of Functional Foods 78, pages 104389.
Crossref
Teresa Delerue, M. Fátima Barroso, Mónica Dias-Teixeira, Maria Figueiredo-González, Cristina Delerue-Matos & Clara Grosso. (2021) Interactions between Ginkgo biloba L. and Scutellaria baicalensis Georgi in multicomponent mixtures towards cholinesterase inhibition and ROS scavenging. Food Research International 140, pages 109857.
Crossref
Juan Liu, Wuwen Feng & Cheng Peng. (2021) A Song of Ice and Fire: Cold and Hot Properties of Traditional Chinese Medicines. Frontiers in Pharmacology 11.
Crossref
Xuehong Nöst, Eva-Maria Pferschy-Wenzig, Xiao-Tong Yu, Min Li, Xiao-Lin Tong & Rudolf Bauer. (2021) Comprehensive metabolic profiling of modified gegen qinlian decoction by ultra-high-performance liquid chromatography-diode array detection-Q-exactive-orbitrap-electrospray ionization-mass spectrometry/mass spectrometry and application of high-performance thin-layer chromatography for its fingerprint analysis. World Journal of Traditional Chinese Medicine 7:1, pages 11.
Crossref
Tong-Hua Zhang, Jian-Xin Liang, Deng-Lu Long, Min Ma, Li-Guo Chen, Da-Xiang Lu, Xiao-Hua Jiang, Xue-Song Yang & Guang Wang. (2021) Tocolysis effects of traditional Chinese medicine and their effective components. World Journal of Traditional Chinese Medicine 0:0, pages 0.
Crossref
Zixin Shu, Kai Chang, Yana Zhou, Chaoan Peng, Xugui Li, Wei Cai, Li Wei, Qiguang Zheng, Haoyu Tian, Jianan Xia, Kuo Yang, Ning Wang, Jifen Liu, Xiaojun Min, Dengying Yan, Jing Sun, Huan Wu, Xiaomeng Li, Yi Zheng, Zecong Yu, Xi Lu, Yuxia Yang, Ting Jia, Jinghui Ji, Qunzheng Zou, Yinyan Wang, Minzhong Xiao, Qing Zhang, Yajuan Xiong, Feng Sun, Qiang Zhu, Xingxing Jiang, Guodong Wang, Sydney Chi-Wai Tang, Junhua Zhang, Xiuyang Li, Nevin Zhang, Boli Zhang, Xiaolin Tong, Baoyan Liu, Xuezhong Zhou, Kam Wa Chan & Xiaodong Li. (2021) Add-On Chinese Medicine for Coronavirus Disease 2019 (ACCORD): A Retrospective Cohort Study of Hospital Registries. The American Journal of Chinese Medicine 49:03, pages 543-575.
Crossref
Kun Chen, Wei Wu, Xiudan Hou, Qingli Yang & Zhaojie Li. (2021) A review: antimicrobial properties of several medicinal plants widely used in Traditional Chinese Medicine. Food Quality and Safety 5.
Crossref
Jie Shen, Pei Li, Shuangshuang Liu, Qing Liu, Yue Li, Yuhua Sun, Chunnian He & Peigen Xiao. (2021) Traditional uses, ten-years research progress on phytochemistry and pharmacology, and clinical studies of the genus Scutellaria. Journal of Ethnopharmacology 265, pages 113198.
Crossref
Halina Ekiert, Paweł Kubica, Inga Kwiecień, Karolina Jafernik, Marta Klimek-Szczykutowicz & Agnieszka Szopa. 2020. Plant Antioxidants and Health. Plant Antioxidants and Health 1 44 .
Beata Kawka, Inga Kwiecień & Halina Maria Ekiert. 2021. Plant Cell and Tissue Differentiation and Secondary Metabolites. Plant Cell and Tissue Differentiation and Secondary Metabolites 249 272 .
Yoana Georgieva, Mariana Katsarova, Plamen Stoyanov, Rumen Mladenov, Petko Denev, Desislava Teneva, Evgeniy Plotnikov, Petko Bozov & Stela Dimitrova. (2020) Metabolite Profile and Antioxidant Activity of Some Species of Genus Scutellaria Growing in Bulgaria. Plants 10:1, pages 45.
Crossref
Jia-Wen Song, Jia-Ying Long, Long Xie, Lin-Lin Zhang, Qing-Xuan Xie, Hui-Juan Chen, Mao Deng & Xiao-Fang Li. (2020) Applications, phytochemistry, pharmacological effects, pharmacokinetics, toxicity of Scutellaria baicalensis Georgi. and its probably potential therapeutic effects on COVID-19: a review. Chinese Medicine 15:1.
Crossref
Chengke Bai, Jingjing Yang, Bo Cao, Ying Xue, Pufan Gao, Hui Liang & Guishuang Li. (2020) Growth years and post-harvest processing methods have critical roles on the contents of medicinal active ingredients of Scutellaria baicalensis. Industrial Crops and Products 158, pages 112985.
Crossref
Do Luong Huynh, Tran Hoang Ngau, Nguyen Hoai Nguyen, Gia-Buu Tran & Cuong Thach Nguyen. (2020) Potential therapeutic and pharmacological effects of Wogonin: an updated review. Molecular Biology Reports 47:12, pages 9779-9789.
Crossref
Alena Liskova, Lenka Koklesova, Marek Samec, Elizabeth Varghese, Mariam Abotaleb, Samson Mathews Samuel, Karel Smejkal, Kamil Biringer, Martin Petras, Dana Blahutova, Ondrej Bugos, Martin Pec, Marian Adamkov, Dietrich Büsselberg, Rachele Ciccocioppo, Mariusz Adamek, Luis Rodrigo, Martin Caprnda, Peter Kruzliak & Peter Kubatka. (2020) Implications of flavonoids as potential modulators of cancer neovascularity. Journal of Cancer Research and Clinical Oncology 146:12, pages 3079-3096.
Crossref
Xiaonan Liu, Jian Cheng, Xiaoxi Zhu, Guanghui Zhang, Shengchao Yang, Xiaoxian Guo, Huifeng Jiang & Yanhe Ma. (2020) De Novo Biosynthesis of Multiple Pinocembrin Derivatives in Saccharomyces cerevisiae . ACS Synthetic Biology 9:11, pages 3042-3051.
Crossref
Laiyun Xin, Jialiang Gao, Hongchen Lin, Yi Qu, Chang Shang, Yuling Wang, Yingdong Lu & Xiangning Cui. (2020) Regulatory Mechanisms of Baicalin in Cardiovascular Diseases: A Review. Frontiers in Pharmacology 11.
Crossref
Yuanyuan Li, Ke Song, Hanlai Zhang, Mengchen Yuan, Na An, Yufei Wei, Liqin Wang, Yikun Sun, Yanwei Xing & Yonghong Gao. (2020) Anti-inflammatory and immunomodulatory effects of baicalin in cerebrovascular and neurological disorders. Brain Research Bulletin 164, pages 314-324.
Crossref
Natalia Cichon, Joanna Saluk-Bijak, Leslaw Gorniak, Lukasz Przyslo & Michal Bijak. (2020) Flavonoids as a Natural Enhancer of Neuroplasticity—An Overview of the Mechanism of Neurorestorative Action. Antioxidants 9:11, pages 1035.
Crossref
Chaoyue Wang, Guanglei Zuo, Xiang Wang, Hyun Yong Kim, Shanshan Zhao, Wenyu Sun, Shengqiang Tong & Soon Sung Lim. (2020) Retention mechanism of pH‐peak‐focusing in countercurrent chromatographic separation of baicalin and wogonoside from Scutellaria baicalensis Georgi . Journal of Separation Science 43:19, pages 3806-3815.
Crossref
Lyubov Dyshlyuk, Anastasia Dmitrieva, Svetlana Ivanova, Yuliya Golubtsova & Lev Ostroumov. (2020) Panax ginseng callus, suspension, and root cultures: extraction and qualitative analysis. Foods and Raw Materials 8:2, pages 369-376.
Crossref
Ying Shen, Wei Cong, Ai-hua Zhang & Xiangcai Meng. (2020) Complexity of active medicinal ingredients in radix scutellariae with sodium hydrosulfite exposure. PLOS ONE 15:9, pages e0238927.
Crossref
Yi-Teng Xia, Gallant Kar-Lun Chan, Huai-You Wang, Tina Ting-Xia Dong, Ran Duan, Wei-Hui Hu, Qi-Wei Qin, Wen-Xiong Wang & Karl Wah-Keung Tsim. (2020) The anti-bacterial effects of aerial parts of Scutellaria baicalensis: Potential application as an additive in aquaculture feedings. Aquaculture 526, pages 735418.
Crossref
Alena Liskova, Lenka Koklesova, Marek Samec, Karel Smejkal, Samson Mathews Samuel, Elizabeth Varghese, Mariam Abotaleb, Kamil Biringer, Erik Kudela, Jan Danko, Mehdi Shakibaei, Taeg Kyu Kwon, Dietrich Büsselberg & Peter Kubatka. (2020) Flavonoids in Cancer Metastasis. Cancers 12:6, pages 1498.
Crossref
Pengfei Hao, Yiyi Xiong, Hezhen Wu & Yanfang Yang. (2020) Network Pharmacology Research and Preliminary Verification of Gegen Qinlian Decoction for the Treatment of Non-Alcoholic Fatty Liver Disease. Natural Product Communications 15:5, pages 1934578X2092002.
Crossref
Robert D. Hoffman, Chang-Yu Li, Kai He, Xiaoxing Wu, Bai-Cheng He, Tong-Chuan He & Jian-Li Gao. (2020) Chinese Herbal Medicine and Its Regulatory Effects on Tumor Related T Cells. Frontiers in Pharmacology 11.
Crossref
Jianfeng Liu, Tianhua Zhang, Yingying Wang, Chengqing Si, Xudong Wang, Rui-Tao Wang & Zhonghua Lv. (2020) Baicalin ameliorates neuropathology in repeated cerebral ischemia-reperfusion injury model mice by remodeling the gut microbiota. Aging 12:4, pages 3791-3806.
Crossref
AnnaYurievna Stepanova, AlexandraIvanovna Solov'yova & SvetlanaAndreevna Salamaikina. (2020) Influence of spectral light composition on flavones formation in callus culture of Scutellaria baicalensis georgi. Pharmacognosy Magazine 16:67, pages 156.
Crossref
Jinjing WangFanghua QiZhixue WangZhikun ZhangNi PanLei HuaiShuyu QuLin Zhao. (2019) A review of traditional Chinese medicine for treatment of glioblastoma. BioScience Trends 13:6, pages 476-487.
Crossref
Li Cheng, Wen Liu, Tao Zhang, Ting Xu, Yi-Xuan Shu, Bo Yuan, Ying-Ming Yang & Tao Hu. (2019) Evaluation of the effect of a toothpaste containing Pudilan extract on inhibiting plaques and reducing chronic gingivitis: A randomized, double-blinded, parallel controlled clinical trial. Journal of Ethnopharmacology 240, pages 111870.
Crossref
Zilong Wang, Shuang Wang, Zheng Xu, Mingwei Li, Kuan Chen, Yaqun Zhang, Zhimin Hu, Meng Zhang, Zhiyong Zhang, Xue Qiao & Min Ye. (2019) Highly Promiscuous Flavonoid 3- O -Glycosyltransferase from Scutellaria baicalensis . Organic Letters 21:7, pages 2241-2245.
Crossref
Beata Kawka, Inga Kwiecień & Halina Ekiert. 2019. Plant Cell and Tissue Differentiation and Secondary Metabolites. Plant Cell and Tissue Differentiation and Secondary Metabolites 1 24 .
Hsiaoyu Yang, Yuexiang Ming, Weihsin Wang, Yipeng Jin, Zhihui Hao, Gang Liu, Di Zhang & Jiahao Lin. (2022) Anti-Inflammatory and Anti-Pruritic Effects of Chi-Huang Solution in a Murine Model of Allergic Contact Dermatitis. SSRN Electronic Journal.
Crossref