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Pharmaceutical Biology Volume 59, 2021 - Issue 1
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Research Article

Rosmarinic acid ameliorates acetaminophen-induced acute liver injury in mice via RACK1/TNF-α mediated antioxidant effect

Yang Yua Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, PR China;b Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, PR ChinaView further author information
,
Yao Wub Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, PR China;c NHC Key Laboratory of Chronobiology, Sichuan University, Chengdu, PR ChinaView further author information
,
Hao-zheng Yanb Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, PR China;d West China School of Medicine, Sichuan University, Chengdu, PR ChinaView further author information
,
Zi-ru Xiab Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, PR China;d West China School of Medicine, Sichuan University, Chengdu, PR ChinaView further author information
,
Wen Wenb Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, PR China;d West China School of Medicine, Sichuan University, Chengdu, PR ChinaView further author information
,
Dan-yang Liub Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, PR China;c NHC Key Laboratory of Chronobiology, Sichuan University, Chengdu, PR ChinaView further author information
&
Li-hong Wanb Department of Pharmacology, West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu, PR China;c NHC Key Laboratory of Chronobiology, Sichuan University, Chengdu, PR ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0086-8857View further author information
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Pages 1284-1291 | Received 12 Sep 2020, Accepted 25 Aug 2021, Published online: 13 Sep 2021

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Yu-Qing Zeng, Jin-Tao He, Bo-Yong Hu, Wen Li, Jing Deng, Qin-Lu Lin & Yong Fang. (2024) Virgin coconut oil: A comprehensive review of antioxidant activity and mechanisms contributed by phenolic compounds. Critical Reviews in Food Science and Nutrition 64:4, pages 1052-1075.
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Xiong Zhang, Chenlin Su, Shuxin Zhao, Ji Li & Feng Yu. (2022) Combination therapy of Ulinastatin with Thrombomodulin alleviates endotoxin (LPS) - induced liver and kidney injury via inhibiting apoptosis, oxidative stress and HMGB1/TLR4/NF-κB pathway. Bioengineered 13:2, pages 2951-2970.
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Articles from other publishers (10)

Dan-yang Liu, Yao Wu, Zi-qi Feng, Yang Yu, Hua-wei Cai, Shi-ping Liao, Tao Zeng, Ling Zhu, Xia Wang & Li-hong Wan. (2024) Rosmarinic acid against cognitive impairment via RACK1/HIF-1α regulated microglial polarization in sepsis-surviving mice. Chemico-Biological Interactions 388, pages 110830.
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Chih-Min Yang, Mei-Yin Chien, Li-Yu Wang, Cheng-Hung Chuang & Chao-Hsiang Chen. (2022) Goji Ferment Ameliorated Acetaminophen-Induced Liver Injury in vitro and in vivo. Probiotics and Antimicrobial Proteins 15:5, pages 1102-1112.
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Peng Tang, Huiyin Wu, Mengru Wang, Ruihan Zhang, Bin Liang, Xiaoli Li & Weilie Xiao. (2023) Self-Assembled Poly(rosmarinic acid) Nanoantioxidant for Enhanced Acute Liver Injury Treatment. ACS Applied Nano Materials 6:18, pages 16392-16399.
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Suphachai Charoensin & Suwatsak Dansakda. (2023) Modulatory Effect of Rosmarinic Acid on H2O2-Induced Adaptive Glycolytic Response in Dermal Fibroblasts. Molecules 28:14, pages 5599.
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Pooja Ravaria, Priyanka Saxena, Shruti Laksmi BS, Vikas Ranjan, Syed Wasfi Fatma Abidi, Priyanka Saha, Siva Ramamoorthy, Faraz Ahmad & Sandeep Singh Rana. (2023) Molecular mechanisms of neuroprotective offerings by rosmarinic acid against neurodegenerative and other CNS pathologies. Phytotherapy Research 37:5, pages 2119-2143.
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Mayada R. Farag, Claudia Zizzadoro, Mahmoud Alagawany, Shimaa M. Abou-Zeid, Suzan Attia Mawed, Mohamed S. El Kholy, Alessandro Di Cerbo, Mahmoud M. Azzam, Eman A.A. Mahdy, Mariam H.E. Khedr & Walaa M. Elhady. (2023) In ovo protective effects of chicoric and rosmarinic acids against Thiacloprid-induced cytotoxicity, oxidative stress, and growth retardation on newly hatched chicks. Poultry Science 102:4, pages 102487.
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Ali Kakanezhadi, Mehrdad Rezaei, Abbas Raisi, Omid Dezfoulian, Farshid Davoodi & Hassan Ahmadvand. (2022) Rosmarinic acid prevents post-operative abdominal adhesions in a rat model. Scientific Reports 12:1.
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Yang Yao, Rong Li, Dan Liu, Lihui Long & Na He. (2022) Rosmarinic acid alleviates acetaminophen-induced hepatotoxicity by targeting Nrf2 and NEK7-NLRP3 signaling pathway. Ecotoxicology and Environmental Safety 241, pages 113773.
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Saba Noor, Taj Mohammad, Malik Abdul Rub, Ali Raza, Naved Azum, Dharmendra Kumar Yadav, Md Imtaiyaz Hassan & Abdullah M. Asiri. (2022) Biomedical features and therapeutic potential of rosmarinic acid. Archives of Pharmacal Research 45:4, pages 205-228.
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Jie Zhao, Xiaotong Lv, Yan Huo, Xiaodi Hu, Xiaochen Li, Shizhuo Sun, Xin Zhao, Xuewei Kong & Jialin Xu. (2021) Hepatocyte-Specific Deficiency of BAP31 Amplified Acetaminophen-Induced Hepatotoxicity via Attenuating Nrf2 Signaling Activation in Mice. International Journal of Molecular Sciences 22:19, pages 10788.
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