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Pharmaceutical Biology Volume 59, 2021 - Issue 1

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Research Article

Genistein alleviates H₂O₂-induced senescence of human umbilical vein endothelial cells via regulating the TXNIP/NLRP3 axis

Guihua Wua Department of Geriatrics, Nantong First Geriatric Hospital, Nantong City, China

Siming Lib Department of Geriatrics, Harbin Second Hospital, Harbin, China

Guangjin Quc Cadre Ward of The First Affiliated Hospital of Harbin Medical University, Harbin City, China

Jiajia Huad Department of Traditional Chinese Medicine, Nantong First Elderly Hospital, Nantong City, China

Jing Zonga Department of Geriatrics, Nantong First Geriatric Hospital, Nantong City, China

Xiaofeng Lie Department of Otolaryngology, East Hospital, Shanghai Sixth People's Hospital, Nanhui New City, China

Fanghui Xub Department of Geriatrics, Harbin Second Hospital, Harbin, ChinaCorrespondence[email protected]

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Pages 1386-1399 | Received 25 Feb 2021, Accepted 06 Sep 2021, Published online: 18 Oct 2021

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https://doi.org/10.1080/13880209.2021.1979052
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Wanglin Dong, Qianwen Peng, Zhuoxin Liu, Zhenxing Xie, Xiajun Guo, Yuanyuan Li & Chaoran Chen. (2023) Estrogen plays an important role by influencing the NLRP3 inflammasome. Biomedicine & Pharmacotherapy 167, pages 115554.
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Hao Li & Qi Zhang. (2023) Research Progress of Flavonoids Regulating Endothelial Function. Pharmaceuticals 16:9, pages 1201.
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Laura Locatelli, Giorgia Fedele & Jeanette A. Maier. (2023) The Role of Txnip in Mediating Low-Magnesium-Driven Endothelial Dysfunction. International Journal of Molecular Sciences 24:9, pages 8351.
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Xue Wang, Jiaqi Zhang, Chengkui Xiu, Jing Yang, Yiqing Liu & Yan Lei. (2023) Whole-transcriptome sequencing analysis reveal mechanisms of Yiqi Huoxue Yangyin (YHY) decoction in ameliorating D-gal-induced cardiac aging. Aging.
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Fares E.M Ali, Islam M. Ibrahim, Osama M Ghogar, Esraa K. Abd-alhameed, Hanan S. Althagafy & Emad H.M. Hassanein. (2023) Therapeutic interventions target the NLRP3 inflammasome in ulcerative colitis: Comprehensive study. World Journal of Gastroenterology 29:6, pages 1026-1053.
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Peng Zhou, Yao-yao Ma, Xiao-ni Zhao & Fang Hua. (2023) Phytochemicals as potential target on thioredoxin-interacting protein (TXNIP) for the treatment of cardiovascular diseases. Inflammopharmacology 31:1, pages 207-220.
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Jie Xiang, Jun Shen, Ling Zhang & Baopeng Tang. (2022) Identification and validation of senescence-related genes in circulating endothelial cells of patients with acute myocardial infarction. Frontiers in Cardiovascular Medicine 9.
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Jiang Wen, Caixia LiuChangqing Deng. (2022) Research progress on the mechanism of aging of vascular endothelial cells and the intervention of traditional Chinese medicine: A review. Medicine 101:49, pages e32248.
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Bhawna Diwan & Rohit Sharma. (2022) Nutritional components as mitigators of cellular senescence in organismal aging: a comprehensive review. Food Science and Biotechnology 31:9, pages 1089-1109.
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Yanpei Gu, Fan Xue, Hongrui Xiao, Lihuan Chen & Ying Zhang. (2022) Bamboo Leaf Flavonoids Suppress Oxidative Stress-Induced Senescence of HaCaT Cells and UVB-Induced Photoaging of Mice through p38 MAPK and Autophagy Signaling. Nutrients 14:4, pages 793.
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Ainara González-Moro, Inés Valencia, Licia Shamoon, Carlos Félix Sánchez-Ferrer, Concepción Peiró & Fernando de la Cuesta. (2022) NLRP3 Inflammasome in Vascular Disease: A Recurrent Villain to Combat Pharmacologically. Antioxidants 11:2, pages 269.
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Genistein alleviates H₂O₂-induced senescence of human umbilical vein endothelial cells via regulating the TXNIP/NLRP3 axis

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Genistein alleviates H2O2-induced senescence of human umbilical vein endothelial cells via regulating the TXNIP/NLRP3 axis

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Genistein alleviates H₂O₂-induced senescence of human umbilical vein endothelial cells via regulating the TXNIP/NLRP3 axis