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Pharmaceutical Biology Volume 60, 2022 - Issue 1
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Research Article

Acteoside and ursolic acid synergistically protects H2O2-induced neurotrosis by regulation of AKT/mTOR signalling: from network pharmacology to experimental validation

Yan-Jie Qua Department of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China;b Department of Traditional Chinese Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, ChinaView further author information
,
Min-Rui Dinga Department of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaView further author information
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Chao Gua Department of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaView further author information
,
Li-Min Zhanga Department of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaView further author information
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Rong-Rong Zhena Department of Neurology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaView further author information
,
Jin-Fang Chenc Department of Oncology, Institute of Traditional Chinese Medicine in Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaView further author information
,
Bing Huc Department of Oncology, Institute of Traditional Chinese Medicine in Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaCorrespondence[email protected]
View further author information
&
Hong-Mei And Department of Science & Technology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, ChinaCorrespondence[email protected]
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Pages 1751-1761 | Received 23 Aug 2021, Accepted 30 Jun 2022, Published online: 14 Sep 2022

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Jinhao Jia, Jianfei Chen, Guoli Wang, Minjing Li, Qiusheng Zheng & Defang Li. (2023) Progress of research into the pharmacological effect and clinical application of the traditional Chinese medicine Rehmanniae Radix. Biomedicine & Pharmacotherapy 168, pages 115809.
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Yi Zhao, Sijia Wang, Jin Pan & Ke Ma. (2023) Verbascoside: A neuroprotective phenylethanoid glycosides with anti-depressive properties. Phytomedicine 120, pages 155027.
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Yunxia Sun, Xintao Ni, Siyao Cheng, Xiaofeng Yu, Xiaoqin Jin, Liangxin Chen, Zhenggang Yang, Daozong Xia, Zhe Chen, Miaofen G. Hu & Xiaoli Hou. (2023) Acteoside improves adipocyte browning by CDK6-mediated mTORC1-TFEB pathway. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1868:9, pages 159364.
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Xiao Zhang, Yaping Guo, Zhonghong Zhang, Xintong Wu, Li Li, Zhiping Yang & Zhipeng Li. (2023) Neuroprotective effects of bavachin against neuroinflammation and oxidative stress-induced neuronal damage via activation of Sirt1/Nrf2 pathway and inhibition of NF-κB pathway. Journal of Functional Foods 107, pages 105655.
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Lipeng Wu, Weisu Huang, Kejie Peng, Yixuan Wang, Qi Chen & Baiyi Lu. (2023) Enhancing the stability, BBB permeability and neuroprotective activity of verbascoside in vitro using lipid nanocapsules in combination with menthol. Food Chemistry 414, pages 135682.
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