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Review Article

New insights toward the pathogenesis of ankylosing spondylitis; genetic variations and epigenetic modifications

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Pages 198-209 | Received 03 Apr 2016, Accepted 04 Jun 2016, Published online: 18 Jul 2016

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Hamidreza Ebrahimiyan, Farhad Gharibdoost, Saeed Aslani, Hoda Kavosi, Faraneh Farsad, Ahmadreza Jamshidi & Mahdi Mahmoudi. (2020) microRNAs are potentially regulating the survivin gene in PBMCs from systemic sclerosis patients. Modern Rheumatology 30:5, pages 862-869.
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Hongyun Liu, Bin Wang & Qiliang Zhang. (2021) Connection of COX‐2 variants to ankylosing spondylitis susceptibility . Journal of Cellular Physiology 238:10, pages 2528-2532.
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Fanyan Meng, Ningna Du, Daoming Xu, Li Kuai, Lanying Liu & Minning Xiu. (2021) Bioinformatics Analysis of the Molecular Mechanism and Potential Treatment Target of Ankylosing Spondylitis. Computational and Mathematical Methods in Medicine 2021, pages 1-11.
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Hamideh Aghaei, Elham Farhadi, Maryam Akhtari, Sara Shahba, Shayan Mostafaei, Ahmadreza Jamshidi, Shiva Poursani, Mahdi Mahmoudi & Mohammad Hossein Nicknam. (2020) Copy number variation of IL17RA gene and its association with the ankylosing spondylitis risk in Iranian patients: a case-control study. BMC Medical Genetics 21:1.
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Yanhui Liu, Guohui Zhang, Yulong Guan, Xiaoliang Zhao, Quan Wang, Hua Li & Jinhong Qi. (2020) Association of IFN‐γ polymorphisms with ankylosing spondylitis risk . Journal of Cellular and Molecular Medicine 24:18, pages 10615-10620.
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A Türkyilmaz, P Ata, F Akbaş & İ Yağci. (2020) The expression levels of microRNAs associated with T and B cell differentiation/stimulation in ankylosing spondylitis. Balkan Journal of Medical Genetics 23:1, pages 25-32.
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Daniel E. Furst & James S. Louie. (2019) Targeting inflammatory pathways in axial spondyloarthritis. Arthritis Research & Therapy 21:1.
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Wei Zhu, Xuxia He, Kaiyuan Cheng, Linjie Zhang, Di Chen, Xiao Wang, Guixing Qiu, Xu Cao & Xisheng Weng. (2019) Ankylosing spondylitis: etiology, pathogenesis, and treatments. Bone Research 7:1.
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Yu-Cong Zou, Yan-Ping Gao, Hai-Dong Yin & Gang Liu. (2019) Serum miR-21 expression correlates with radiographic progression but also low bone mineral density in patients with ankylosing spondylitis: a cross-sectional study. Innate Immunity 25:5, pages 314-321.
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Betül Sargın, Ayla Akbal, Hatice Resorlu, Yılmaz Savaş, Coşkun Zateri, Fatma Sılan & Öztürk Özdemir. (2017) The frequency of toll-like receptor 4 gene polymorphism in ankylosing spondylitis and its relationship between disease activity. The European Research Journal.
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J Karami, M Mahmoudi, A Amirzargar, M Gharshasbi, A Jamshidi, S Aslani & M H Nicknam. (2017) Promoter hypermethylation of BCL11B gene correlates with downregulation of gene transcription in ankylosing spondylitis patients. Genes & Immunity 18:3, pages 170-175.
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Bei Jia & Xiangbei Qi. (2017) The genetic association between polymorphisms in lymphotoxin-α gene and ankylosing spondylitis susceptibility in Chinese group. Medicine 96:19, pages e6796.
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Marzia Dolcino, Elisa Tinazzi, Andrea Pelosi, Giuseppe Patuzzo, Francesca Moretta, Claudio Lunardi & Antonio Puccetti. (2017) Gene Expression Analysis before and after Treatment with Adalimumab in Patients with Ankylosing Spondylitis Identifies Molecular Pathways Associated with Response to Therapy. Genes 8:4, pages 127.
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Friedrich C. Luft. (2016) Mesenchymal stem cells provide novel insights into ankylosing spondylitis. Journal of Molecular Medicine 95:2, pages 119-121.
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