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Modern Rheumatology Volume 27, 2017 - Issue 6
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Original Article

Certolizumab Pegol treatment in Behcet’s disease with different organ involvement: A multicenter retrospective observational study

Giuseppe LopalcoDepartment of Emergency and Organ Transplantation, Rheumatology Unit, University of Bari, Bari, Italy;
,
Giacomo EmmiDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy;
,
Stefano GentileschiResearch Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy;
,
Silvana GuerrieroDepartment of Neurosciences and Sense Organs, University of Bari, Bari, Italy;
,
Antonio VitaleResearch Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy;
,
Elena SilvestriDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy;
,
Matteo BecattiDepartment of Experimental and Clinical Biomedical Sciences “Mario Serio”, University of Florence, Florence, Italy;
,
Iacopo CavalloDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy;
,
Claudia FabianiDepartment of Ophthalmology, Humanitas Research Hospital, Milan, Italy
,
Bruno FredianiResearch Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy;
,
Florenzo IannoneDepartment of Emergency and Organ Transplantation, Rheumatology Unit, University of Bari, Bari, Italy;
&
Luca CantariniResearch Center of Systemic Autoinflammatory Diseases and Behçet's Disease Clinic, Department of Medical Sciences, Surgery and Neurosciences, University of Siena, Siena, Italy; Correspondence[email protected]
 show all
Pages 1031-1035 | Received 22 Dec 2016, Accepted 16 Jan 2017, Published online: 21 Feb 2017

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Antonio Vitale, Valeria Caggiano, Virginia Berlengiero, Maria Orsetta Perfetti, Jurgen Sota, Gian Marco Tosi, Bruno Frediani, Luca Cantarini & Claudia Fabiani. (2023) Comparing biologic options for the management of Behcet’s disease-related uveitis. Expert Review of Clinical Immunology 19:3, pages 315-328.
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Yesim Ozguler, Sinem Nihal Esatoglu & Gulen Hatemi. (2023) Current pharmacological solutions for Behçet’s syndrome. Expert Opinion on Pharmacotherapy 24:2, pages 221-231.
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Yesim Ozguler, Ayse Ozdede & Gulen Hatemi. (2021) Recent Insights into the Management of Behçet Syndrome. Journal of Inflammation Research 14, pages 3429-3441.
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Burçin Cansu Bozca & Erkan Alpsoy. (2021) Experimental Therapeutic Solutions for Behcet’s Disease. Journal of Experimental Pharmacology 13, pages 127-145.
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Giuseppe Lopalco, Donato Rigante, Antonio Lopalco, Giacomo Emmi, Vincenzo Venerito, Antonio Vitale, Giovanna Capozio, Nunzio Denora, Luca Cantarini & Florenzo Iannone. (2020) Safety of systemic treatments for Behçet’s syndrome. Expert Opinion on Drug Safety 19:10, pages 1269-1301.
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Ilknur Tugal-Tutkun & Pinar Çakar Özdal. (2020) Behçet’s disease uveitis: is there a need for new emerging drugs?. Expert Opinion on Emerging Drugs 25:4, pages 531-547.
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Carla Gaggiano, Jurgen Sota, Stefano Gentileschi, Valeria Caggiano, Salvatore Grosso, Gian Marco Tosi, Bruno Frediani, Luca Cantarini & Claudia Fabiani. (2020) The current status of biological treatment for uveitis. Expert Review of Clinical Immunology 16:8, pages 787-811.
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Maria Soledad Ormaechea, Muhammad Hassan, Neil Onghanseng, Jung Hyun Park, Sarakshi Mahajan, Khalid Yusuf Al-Kirwi, Gunay Uludag, Muhammad Sohail Halim, Ariel Schlaen, Yasir J Sepah, Diana V Do & Quan Dong Nguyen. (2019) Safety of systemic therapy for noninfectious uveitis. Expert Opinion on Drug Safety 18:12, pages 1219-1235.
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Uwe Pleyer, Dominika Pohlmann, Esra Kardeş, Denis Poddubnyy & Judith Rademacher. (2019) Emerging drugs for the treatment of noninfectious uveitis. Expert Opinion on Emerging Drugs 24:3, pages 173-190.
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Articles from other publishers (25)

Jurgen Sota, Adriana Capuano, Giacomo Emmi, Florenzo Iannone, Luca Cantarini, Gulen Hatemi & Giuseppe Lopalco. (2023) Therapeutic approach to central nervous system involvement of Behçet's disease. Seminars in Arthritis and Rheumatism 61, pages 152206.
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João Araújo Correia, Jorge Crespo, Glória Alves, Fernando Salvador, João Matos-Costa, José Delgado Alves, Jorge Fortuna, Isabel Almeida, Ana Campar, Mariana Brandão, Raquel Faria, Daniela Marado, Susana Oliveira, Lelita Santos, Fátima Silva, Carlos Vasconcelos, Milene Fernandes & António Marinho. (2023) Biologic therapy in large and small vessels vasculitis, and Behçet’s disease: Evidence- and practice-based guidance. Autoimmunity Reviews 22:8, pages 103362.
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José Luis Martín-Varillas, Lara Sanchez-Bilbao, Vanesa Calvo-Río, Alfredo Adán, Inés Hernanz, Adela Gallego-Flores, Emma Beltran-Catalan, Sonia Castro-Oreiro, Patricia Fanlo, Alvaro Garcia Martos, Ignacio Torre, Miguel Cordero-Coma, Juan Ramon De Dios, Ángel García-Aparicio, Marisa Hernández-Garfella, Amalia Sánchez-Andrade, Andrea García-Valle, Olga Maiz, Roberto Miguélez, Sergio Rodríguez-Montero, Ana Urruticoechea, Raúl Veroz, Arantxa Conesa, Cristina Fernández-Carballido, Vega Jovaní, Jose J Mondejar, Olga Martínez González, Patricia Moya Alvarado, Susana Romero-Yuste, Paula Rubio-Muñoz, Eva Peña-Sainz-Pardo, Marta Garijo-Bufort, Rosalía Demetrio-Pablo, José L Hernández & Ricardo Blanco. (2022) Long-term follow-up of certolizumab pegol in uveitis due to immune-mediated inflammatory diseases: multicentre study of 80 patients. RMD Open 8:2, pages e002693.
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Simple GuptaK. ShyamsundarMohini Agrawal, Nitin VichareJyotirmay Biswas. (2022) Current Knowledge of Biologics in Treatment of Noninfectious Uveitis. Journal of Ocular Pharmacology and Therapeutics 38:3, pages 203-222.
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Sara Trevisini, Giusto Trevisan, Iris Zalaudek & Serena Bonin. (2022) Adamantiades‐Behçet 's disease therapy: current treatment options and recommendations with regard to the COVID ‐19 pandemic . Dermatologic Therapy 35:3.
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Yusuf Yazici, Gulen Hatemi, Bahram Bodaghi, Jae Hee Cheon, Noburu Suzuki, Nicola Ambrose & Hasan Yazici. (2021) Behçet syndrome. Nature Reviews Disease Primers 7:1.
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Erkan Alpsoy, Burcin Cansu Bozca & Asli Bilgic. (2021) Behçet Disease: An Update for Dermatologists. American Journal of Clinical Dermatology 22:4, pages 477-502.
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Jacquelyn Majerowski & Kenneth B. Gordon. 2021. Comprehensive Dermatologic Drug Therapy. Comprehensive Dermatologic Drug Therapy 287 301.e7 .
Mathilde Leclercq, Anne-Claire Desbois, Fanny Domont, Georgina Maalouf, Sara Touhami, Patrice Cacoub, Bahram Bodaghi & David Saadoun. (2020) Biotherapies in Uveitis. Journal of Clinical Medicine 9:11, pages 3599.
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Ciara O'Grady, Geraldine Quinn, Anna Keogh, Conor O'Keane & Aizuri Murad. (2020) Certolizumab‐induced facial eruption in a pregnant woman with severe Behcet's disease. Dermatologic Therapy 33:6.
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Joshua S. Davis, David Ferreira, Emma Paige, Craig Gedye & Michael Boyle. (2020) Infectious Complications of Biological and Small Molecule Targeted Immunomodulatory Therapies. Clinical Microbiology Reviews 33:3.
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Kader Cetin Gedik, Micol Romano, Roberta A. Berard & Erkan Demirkaya. (2020) An Overview of Conventional and Recent Treatment Options for Behcet’s Disease. Current Treatment Options in Rheumatology 6:2, pages 99-127.
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Rodrigo A. Valenzuela, Iván Flores, Beatriz Urrutia, Francisca Fuentes, Pablo E. Sabat, Carolina Llanos, Loreto Cuitino & Cristhian A. Urzua. (2020) New Pharmacological Strategies for the Treatment of Non-Infectious Uveitis. A Minireview. Frontiers in Pharmacology 11.
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Yehyun Park & Jae Hee Cheon. (2020) Update on the Treatment of Behcet’s Disease of the Small Bowel with Biologic Agents. Current Gastroenterology Reports 22:5.
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Aysun Aksoy, Ayten Yazici, Ahmet Omma, Ayse Cefle, Fatos Onen, Unal Tasdemir, Tulin Ergun, Haner Direskeneli & Fatma Alibaz‐Oner. (2020) Efficacy of TNFα inhibitors for refractory vascular Behçet's disease: A multicenter observational study of 27 patients and a review of the literature. International Journal of Rheumatic Diseases 23:2, pages 256-261.
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Yılmaz Özyazgan & Ilknur Tugal-Tutkun. 2020. Behçet Syndrome. Behçet Syndrome 51 71 .
Vedat Hamuryudan, Ina Kötter & Hasan Tüzün. 2020. Behçet Syndrome. Behçet Syndrome 279 305 .
Sinem Nihal Esatoglu & Gulen Hatemi. (2019) Update on the treatment of Behçet’s syndrome. Internal and Emergency Medicine 14:5, pages 661-675.
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Giacomo Emmi, Alessandra Bettiol, Elena Silvestri, Gerardo Di Scala, Matteo Becatti, Claudia Fiorillo & Domenico Prisco. (2018) Vascular Behçet’s syndrome: an update. Internal and Emergency Medicine 14:5, pages 645-652.
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Alessandra Bettiol, Elena Silvestri, Gerardo Di Scala, Amedeo Amedei, Matteo Becatti, Claudia Fiorillo, Giuseppe Lopalco, Carlo Salvarani, Luca Cantarini, Alessandra Soriano & Giacomo Emmi. (2019) The right place of interleukin-1 inhibitors in the treatment of Behçet’s syndrome: a systematic review. Rheumatology International 39:6, pages 971-990.
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Karina Julian & Bahram Bodaghi. 2019. Advances in the Diagnosis and Management of Uveitis. Advances in the Diagnosis and Management of Uveitis.
Muhammad Hassan, Samendra Karkhur, Jeong H. Bae, Muhammad S. Halim, Maria S. Ormaechea, Neil Onghanseng, Nam V. Nguyen, Rubbia Afridi, Yasir J. Sepah, Diana V. Do & Quan D. Nguyen. (2019) New therapies in development for the management of non‐infectious uveitis: A review. Clinical & Experimental Ophthalmology 47:3, pages 396-417.
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Jihye Park & Jae Hee Cheon. (2018) Anti-Tumor Necrosis Factor Therapy in Intestinal Beh Ccedil;et rsquo;s Disease. Gut and Liver 12:6, pages 623-632.
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Giacomo Emmi, Antonio Vitale, Elena Silvestri, Maria Boddi, Matteo Becatti, Claudia Fiorillo, Claudia Fabiani, Bruno Frediani, Lorenzo Emmi, Gerardo Di Scala, Matteo Goldoni, Alessandra Bettiol, Augusto Vaglio, Luca Cantarini & Domenico Prisco. (2018) Adalimumab-Based Treatment Versus Disease-Modifying Antirheumatic Drugs for Venous Thrombosis in Behçet's Syndrome. Arthritis & Rheumatology 70:9, pages 1500-1507.
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