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Modern Rheumatology Volume 27, 2017 - Issue 6
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Original Article

Maintenance treatment using abatacept with dose reduction after achievement of low disease activity in patients with rheumatoid arthritis (MATADOR) – A prospective, multicenter, single arm pilot clinical trial

Shinsuke YasudaDivision of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan; Correspondence[email protected]
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Kazumasa OhmuraDivision of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan; View further author information
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Hiroshi KanazawaDepartment of Rheumatology, Aomori Prefectural Central Hospital, Aomori, Japan; View further author information
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Takashi KuritaDivision of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan; View further author information
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Yujiro KonDepartment of Internal Medicine, Takikawa Municipal Hospital, Takikawa, Japan; View further author information
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Tomonori IshiiDepartment of Hematology and Rheumatology, Tohoku University Graduate School of Medicine, Sendai, Japan; View further author information
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Yuichiro FujiedaDivision of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan; ;Department of Internal Medicine, Tomakomai City Hospital, Tomakomai, Japan; View further author information
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Satoshi JodoDepartment of Internal Medicine, Tomakomai City Hospital, Tomakomai, Japan; View further author information
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Kazuhide TanimuraHokkaido Medical Center for Rheumatic Diseases, Sapporo, Japan; View further author information
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Michio MinamiDepartment of Rheumatology and Orthopaedic Surgery, Hokkaido Orthopaedic Memorial Hospital, Sapporo, Japan; View further author information
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Tomomasa IzumiyamaHigashisendai Rheumatic Disease Clinic, Sendai, Japan; View further author information
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Takumi MatsumotoDivision of Rheumatology, Kin-ikyo Chuo Hospital, Sapporo, Japan; View further author information
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Yoshiharu AmasakiThe Center for Rheumatic Diseases, Tonan Hospital, Sapporo, Japan; View further author information
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Yoko SuzukiIzumi Himawari Clinic, Sendai, Japan; View further author information
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Hideki KasaharaNTT Sapporo Medical Center, Sapporo, Japan; View further author information
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Naofumi YamauchiKiyota Hospital, Sapporo, Japan; View further author information
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Masaru KatoDivision of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan; View further author information
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Tamotsu KamishimaFaculty of Health Sciences, Hokkaido University, Sapporo, JapanView further author information
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Akito TsutsumiDepartment of Internal Medicine, Takikawa Municipal Hospital, Takikawa, Japan; View further author information
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Hiromitsu TakemoriDepartment of Rheumatology, Aomori Prefectural Central Hospital, Aomori, Japan; View further author information
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Takao KoikeNTT Sapporo Medical Center, Sapporo, Japan; View further author information
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Tatsuya AtsumiDivision of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan; View further author information
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Pages 930-937 | Received 01 Dec 2016, Accepted 11 Jan 2017, Published online: 16 Feb 2017

Citations (5)

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Noriyoshi Ogawa, Hiroyuki Ohashi, Yasuhiro Ota, Kaori Kobori, Motohiro Suzuki, Seiji Tsuboi, Masakatsu Hayakawa, Yoshinori Goto, Taro Karahashi, Osamu Kimoto, Toshiaki Miyamoto, Shogo Furukawa, Kumiko Shimoyama, Daisuke Suzuki & Yuichiro Maekawa. (2019) Multicenter, observational clinical study of abatacept in Japanese patients with rheumatoid arthritis. Immunological Medicine 42:1, pages 29-38.
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Jun Kikuchi, Tsuneo Kondo, Akiko Shibata, Ryota Sakai, Yusuke Okada, Kentaro Chino, Ayumi Okuyama, Takahiko Kurasawa, Hirofumi Takei & Koichi Amano. (2018) Efficacy and tolerability of six-week extended dosing interval with tocilizumab therapy in a prospective cohort as remission maintenance in patients with rheumatoid arthritis. Modern Rheumatology 28:3, pages 444-451.
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Articles from other publishers (3)

Kaleb Michaud, Janet Pope, Mart Laar, Jeffrey R. Curtis, Carol Kannowski, Sarah Mitchell, Judith Bell, Jennifer Workman, Jim Paik, Anabela Cardoso & Peter C. Taylor. (2021) Systematic Literature Review of Residual Symptoms and an Unmet Need in Patients With Rheumatoid Arthritis. Arthritis Care & Research 73:11, pages 1606-1616.
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M. A. Borisova & G. V. Lukina. (2019) Analysis of the use of a selective modulator of cosmulation of T‑lymphocytes abatacept in the treatment of rheumatoid arthritis: data from international clinical practice. Medical alphabet 1:18, pages 13-23.
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Shuzo Yoshida, Takuya Kotani, Yuko Kimura, Yoko Matsumura, Ayaka Yoshikawa, Nao Tokai, Takuro Ozaki, Koji Nagai, Toru Takeuchi, Shigeki Makino & Shigeki Arawaka. (2019) Efficacy of abatacept tapering therapy for sustained remission in patients with rheumatoid arthritis: Prospective single-center study. International Journal of Rheumatic Diseases 22:1, pages 81-89.
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