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Modern Rheumatology Volume 29, 2019 - Issue 4

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Original Article

KL-6 is a long-term disease-activity biomarker for interstitial lung disease associated with polymyositis/dermatomyositis, but is not a short-term disease-activity biomarker

Masanori HanaokaInstitute of Rheumatology, Tokyo Women's Medical University, Tokyo, JapanView further author information

Yasuhiro KatsumataInstitute of Rheumatology, Tokyo Women's Medical University, Tokyo, JapanCorrespondence[email protected]
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Hidenaga KawasumiInstitute of Rheumatology, Tokyo Women's Medical University, Tokyo, JapanView further author information

Yasushi KawaguchiInstitute of Rheumatology, Tokyo Women's Medical University, Tokyo, JapanView further author information

Hisashi YamanakaInstitute of Rheumatology, Tokyo Women's Medical University, Tokyo, JapanView further author information

Pages 625-632 | Received 05 Feb 2018, Accepted 05 Jun 2018, Published online: 08 Jan 2019

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https://doi.org/10.1080/14397595.2018.1553488
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Xing He, Jiaqi Ji, Xixi Chen, Zeli Luo, Siyu Fang, Haiying Yan & Lu Guo. (2023) Serum ferritin as a significant biomarker for patients with idiopathic inflammatory myopathy-associated interstitial lung disease: A systematic review and meta-analysis. Seminars in Arthritis and Rheumatism, pages 152350.
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Fengqin Wei, Xinran Zhang, Shengnan Yang, Jing Geng, Bingbing Xie, Yanhong Ren & Huaping Dai. (2023) Evaluation of the Clinical Value of KL-6 and Tumor Markers in Primary Sjögren’s Syndrome Complicated with Interstitial Lung Disease. Journal of Clinical Medicine 12:15, pages 4926.
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Aaron Teel, Jielin Lu, Jane Park, Namisha Singh & Pari Basharat. (2022) The Role of Myositis-Specific Autoantibodies and the Management of Interstitial Lung Disease in Idiopathic Inflammatory Myopathies: A Systematic Review. Seminars in Arthritis and Rheumatism 57, pages 152088.
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Li Shanshan, Zhang Yamei, Zhang Ling, Lu Xin & Wang Guochun. (2021) Progranulin correlated with rapid progressive interstitial lung disease in dermatomyositis with anti-melanoma differentiation-associated gene 5 antibody. Clinical Rheumatology 41:3, pages 757-763.
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Yueyan Lou, Qing Wei, Bijun Fan, Liyan Zhang, Xiaodong Wang, Zhiwei Chen, Xiaoming Tan & Yu Zheng. (2021) The composition of the lung microbiome differs between patients with dermatomyositis and rheumatoid arthritis associated with interstitial lung disease. FEBS Open Bio 12:1, pages 258-269.
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R. El-Beheidy, A.M. Domouky, H. Zidan & Y.A. Amer. (2021) Serum KL-6 as predictive and prognostic marker of interstitial lung disease in childhood connective tissue diseases: a pilot study. Reumatismo 73:3.
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Sara Remuzgo-Martínez, Belén Atienza-Mateo, J. Gonzalo Ocejo-Vinyals, Fernanda Genre, Verónica Pulito-Cueto, Víctor M. Mora-Cuesta, David Iturbe-Fernández, Leticia Lera-Gómez, Raquel Pérez-Fernández, Diana Prieto-Peña, Juan Irure, Fredeswinda Romero-Bueno, Olga Sanchez-Pernaute, Rodrigo Alonso-Moralejo, Laura Nuño, Gema Bonilla, Esther F. Vicente-Rabaneda, Ignacio Grafia, Sergio Prieto-González, Javier Narvaez, Ernesto Trallero-Araguas, Albert Selva-O’Callaghan, Norberto Ortego-Centeno, Nair Pérez-Gómez, Antonio Mera, Julia Martínez-Barrio, Clara Moriano, Elvira Díez, Jaime Calvo-Alén, Alejandro Balsa, María Piedad Ussetti, Rosalía Laporta, Cristina Berastegui, Amparo Solé, Oreste Gualillo, Lorenzo Cavagna, José M. Cifrián, Elisabetta A. Renzoni, Santos Castañeda, Raquel López-Mejías & Miguel A. González-Gay. (2021) Role of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome. Scientific Reports 11:1.
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Yuichiro Shirai, Ryosuke Fukue, Yuko Kaneko & Masataka Kuwana. (2021) Clinical Relevance of the Serial Measurement of Krebs von den Lungen-6 Levels in Patients with Systemic Sclerosis-Associated Interstitial Lung Disease. Diagnostics 11:11, pages 2007.
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Titah Dhadhari Suryananda & Resti Yudhawati. (2021) Association of serum KL-6 levels on COVID-19 severity: A cross-sectional study design with purposive sampling. Annals of Medicine and Surgery 69, pages 102673.
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Yueyan Lou, Yu Zheng, Bijun Fan, Liyan Zhang, Feng Zhu, Xiaodong Wang, Zhiwei Chen, Xiaoming Tan & Qing Wei. (2020) Serum levels of interleukins and S100A8/A9 correlate with clinical severity in patients with dermatomyositis-associated interstitial lung disease. BMC Pulmonary Medicine 20:1.
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Latika Gupta & Hector Chinoy. (2020) Monitoring disease activity and damage in adult and juvenile idiopathic inflammatory myopathy. Current Opinion in Rheumatology 32:6, pages 553-561.
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Ayse Ayzit Kilinc, Asli Arslan, Mehmet Yildiz, Mine Kucur, Amra Adrovic, Kenan Barut, Sezgin Sahin, Haluk Cokugras & Ozgur Kasapcopur. (2019) Serum KL-6 level as a biomarker of interstitial lung disease in childhood connective tissue diseases: a pilot study. Rheumatology International 40:10, pages 1701-1706.
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Yueyan Lou, Yu Zheng, Bijun Fan, Liyan Zhang, Feng Zhu, Xiaodong Wang, Zhiwei Chen & Xiaoming Tan. (2019) Serum S100A12 levels are correlated with clinical severity in patients with dermatomyositis-associated interstitial lung disease. Journal of International Medical Research 48:4, pages 030006051988784.
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. (2020) Fibrosis and Damage Markers in Occupational Interstitial Lung Diseases. EMJ Respiratory.
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Reid Waldman, Madeline E. DeWane & Jun Lu. (2020) Dermatomyositis: Diagnosis and treatment. Journal of the American Academy of Dermatology 82:2, pages 283-296.
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KL-6 is a long-term disease-activity biomarker for interstitial lung disease associated with polymyositis/dermatomyositis, but is not a short-term disease-activity biomarker

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KL-6 is a long-term disease-activity biomarker for interstitial lung disease associated with polymyositis/dermatomyositis, but is not a short-term disease-activity biomarker

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