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Human Fertility
an international, multidisciplinary journal dedicated to furthering research and promoting good practice
Volume 11, 2008 - Issue 1
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Luteal Phase Support

Luteal phase support with GnRH-a improves implantation and pregnancy rates in IVF cycles with endometrium of ≤7 mm on day of egg retrieval

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Pages 43-47 | Published online: 03 Jul 2009

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Francesco M. Fusi, Mariangela Arnoldi, Chiara Bosisio, Grazia Lombardo, Marina Ferrario, Laura Zanga, Alessia Galimberti & Enrica Capitanio. (2015) Ovulation induction and luteal support with GnRH agonist in patients at high risk for hyperstimulation syndrome. Gynecological Endocrinology 31:9, pages 693-697.
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Oshrit Lebovitz & Raoul Orvieto. (2014) Treating patients with “thin” endometrium – an ongoing challenge. Gynecological Endocrinology 30:6, pages 409-414.
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Articles from other publishers (42)

Yigit Cakiroglu, Bulent Tiras, Jason Franasiak & Emre Seli. (2023) Treatment options for endometrial hypoproliferation. Current Opinion in Obstetrics & Gynecology 35:3, pages 254-262.
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TatapudiS V Parvathi Devi, Alka Gahlot, Sangita Sharma, Manisha Choudhary, Ravikant Soni & Meeta Sharma. (2023) Pregnancy outcomes following supplementation of single dose GnRH agonist to sustain the luteal phase in antagonist fresh embryo transfer cycles: A multicentric prospective cohort study. Asian Pacific Journal of Reproduction 12:4, pages 162.
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Margalida Vicens-Vidal, Ana Belén Castel Segui, Joana Amengual Vila, Londa Michailova Niktovenko, Laura Moles García, Andrea Bagur Agulló & Margalida Febrer Castell. (2022) Manejo de endometrio refractario en las pacientes que recibieron técnicas de reproducción asistida: presentación de 2 casos clínicos. Medicina Reproductiva y Embriología Clínica 9:3, pages 100122.
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Yang Liu, Yanzhi Wu, Zhengmei Pan, Fangjie Jiang, Youhui Lu & Yushi Meng. (2022) Single-Dose Versus Multiple-Dose GnRH Agonist for Luteal-Phase Support in Women Undergoing IVF/ICSI Cycles: A Network Meta-Analysis of Randomized Controlled Trials. Frontiers in Endocrinology 13.
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Muhammad Azrai Abu, Jojinah Vindah Alexander, Abdul Kadir Abdul Karim, Mohd Faizal Ahmad & Mohd Hashim Omar. (2022) Single Dose Gonadotropin-Releasing Hormone Agonist Luteal Support in Fresh Embryo Transfer: Variation in Timing, Type, and Dosage. Frontiers in Medicine 9.
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飞 王. (2022) Research Progress of GnRHa Luteal Support in ART. Advances in Clinical Medicine 12:10, pages 9433-9439.
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Loris Marin, Alessandra Andrisani, Luciana Bordin, Francesco Dessole, Marco Noventa, Amerigo Vitagliano, Giampiero Capobianco & Guido Ambrosini. (2021) Sildenafil Supplementation for Women Undergoing Infertility Treatments: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Journal of Clinical Medicine 10:19, pages 4346.
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Jyotsna Pundir & Arri Coomarasamy. 2021. Assisted Reproduction Techniques. Assisted Reproduction Techniques 390 399 .
Ziqi Jin, Hao Shi, Zhiqin Bu, Yihong Guo, Yingchun Su, Hui Song, Mingzhu Huo, Entong Yang, Jingdi Li & Yile Zhang. (2021) Live birth rates after natural cycle versus hormone replacement therapy for single euploid blastocyst transfers: a retrospective cohort study. Reproductive BioMedicine Online.
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Lucía Miguel‐Gómez, Mónica Romeu, Antonio Pellicer & Irene Cervelló. (2021) Strategies for managing Asherman's syndrome and endometrial atrophy: Since the classical experimental models to the new bioengineering approach. Molecular Reproduction and Development 88:8, pages 527-543.
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E.V. Isakova & V.A. Savina. (2021) Thin endometrium in ART treatment and outcome (literature review , part 2). Problemy reproduktsii 27:2, pages 65.
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Ahmed Samy, Ahmed M. Abbas, Ahmed Elmoursi, Mohamed Elsayed & Reda S. Hussein. (2020) Effect of autologous platelet-rich plasma transfusion in the treatment of infertile women with thin endometrium and its implications in IVF cycles: a literature review. Middle East Fertility Society Journal 25:1.
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Nagihan CENGAVER, Tuba MEMUR, Mahmut Kuntay KOKANALI, Gülnur ÖZAKŞİT & Nafiye YILMAZ. (2020) Effect of gonadotropin releasing hormon agonist addition to routine luteal phase support in intracytoplasmic sperm injection-embryo transfer cycles on pregnancy rates and outcomesEffect of gonadotropin releasing hormon agonist addition to routine luteal phase support in intracytoplasmic sperm injection-embryo transfer cycles on pregnancy rates and outcomes. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 17:3, pages 440-445.
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Guy Bar, Avi Harlev, Samira Alfayumi-Zeadna, Atif Zeadna, Ilia Bord, Iris Har-Vardi, Eitan Lunenfeld & Eliahu Levitas. (2020) Recurrent implantation failure: which patients benefit from endometrial scratching prior to IVF?. Archives of Gynecology and Obstetrics 301:3, pages 817-822.
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Noemie Ranisavljevic, Jade Raad, Tal Anahory, Michaël Grynberg & Charlotte Sonigo. (2019) Embryo transfer strategy and therapeutic options in infertile patients with thin endometrium: a systematic review. Journal of Assisted Reproduction and Genetics 36:11, pages 2217-2231.
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Kimberly E. Liu, Michael Hartman & Alex Hartman. (2019) Management of thin endometrium in assisted reproduction: a clinical practice guideline from the Canadian Fertility and Andrology Society. Reproductive BioMedicine Online 39:1, pages 49-62.
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Le Thi Minh Chau, Duong Khue Tu, Philippe Lehert, Do Van Dung, Le Quang Thanh & Vo Minh Tuan. (2019) Clinical pregnancy following GnRH agonist administration in the luteal phase of fresh or frozen assisted reproductive technology (ART) cycles: Systematic review and meta-analysis. European Journal of Obstetrics & Gynecology and Reproductive Biology: X 3, pages 100046.
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Amir Fattahi, Masoud Darabi, Laya Farzadi, Ali Salmassi, Zeinab Latifi, Amir Mehdizadeh, Maghsood Shaaker, Tohid Ghasemnejad, Leila Roshangar & Mohammad Nouri. (2018) Effects of dietary omega-3 and -6 supplementations on phospholipid fatty acid composition in mice uterus during window of pre-implantation. Theriogenology 108, pages 97-102.
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Maryam Eftekhar, Nasim Tabibnejad & Afsar Alsadat Tabatabaie. (2018) The thin endometrium in assisted reproductive technology: An ongoing challenge. Middle East Fertility Society Journal 23:1, pages 1-7.
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S. G. Perminova, E. V. Mityurina & T. S. Amyan. (2018) Modern approaches to the use of gonadotropin-releasing hormone agonists of assisted reproductive technologies. Problemy reproduktsii 24:2, pages 75.
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Youssef Mouhayar & Fady I. Sharara. (2017) Modern management of thin lining. Middle East Fertility Society Journal 22:1, pages 1-12.
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Juan A. Garcia-Velasco, Belen Acevedo, Claudio Alvarez, Monica Alvarez, Jose Bellver, Juan Fontes, Jose Landeras, Dolors Manau, Francisca Martinez, Elkin Muñoz, Ana Robles & Luis Rodriguez-Tabernero. (2016) Strategies to manage refractory endometrium: state of the art in 2016. Reproductive BioMedicine Online 32:5, pages 474-489.
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W. P. Martins, R. A. Ferriani, P. A. Navarro & C. O. Nastri. (2016) GnRH agonist during luteal phase in women undergoing assisted reproductive techniques: systematic review and meta-analysis of randomized controlled trials. Ultrasound in Obstetrics & Gynecology 47:2, pages 144-151.
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Robert K. Hunter, Chris D. Nevitt, Jeremy T. Gaskins, Bradley B. Keller, Henry C. L. Bohler & Amanda J. LeBlanc. (2015) Adipose-Derived Stromal Vascular Fraction Cell Effects on a Rodent Model of Thin Endometrium. PLOS ONE 10:12, pages e0144823.
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M. Gogce, M. Benchaib, S. Hadj, A. Bordes, P. du Menildot, J. Lornage & B. Salle. (2015) Administration d’agonistes de la GnRH (Gonadotrophin Releasing Hormone) en phase lutéale des protocoles substitutifs de transferts d’embryons congelés : étude prospective randomisée. Gynécologie Obstétrique & Fertilité 43:11, pages 728-734.
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Michelle van der Linden, Karen Buckingham, Cindy Farquhar, Jan AM Kremer & Mostafa Metwally. (2015) Luteal phase support for assisted reproduction cycles. Cochrane Database of Systematic Reviews 2016:10.
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Min Xu, Ying-Zhou Tian, Xiu-Jun Zhu, Xi Zhang, Jing-Yan Zhu, Chun-Xiao Gu, Yi Chen & Jian-Ling Huang. (2015) Effect of Xianziyizhen Recipe Capsule on PGI2-PPARδ Signaling Pathway in Embryo Implantation Dysfunction Mice. American Journal of Reproductive Immunology 73:6, pages 545-556.
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Céline Pirard, Ernest Loumaye, Pascale Laurent & Christine Wyns. (2015) Contribution to More Patient-Friendly ART Treatment: Efficacy of Continuous Low-Dose GnRH Agonist as the Only Luteal Support—Results of a Prospective, Randomized, Comparative Study. International Journal of Endocrinology 2015, pages 1-10.
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Gülşah Aynaoğlu Yıldız, Yavuz Emre Şükür, Can Ateş & Ruşen Aytaç. (2014) The addition of gonadotrophin releasing hormone agonist to routine luteal phase support in intracytoplasmic sperm injection and embryo transfer cycles: a randomized clinical trial. European Journal of Obstetrics & Gynecology and Reproductive Biology 182, pages 66-70.
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Hsiao-Fan Kung, Ming-Jer Chen, Hwa-Fen Guua, Ya-Fang Chen, Yu-Chiao Yi, Jason Yen-Ping Ho & Min-Min Chou. (2014) Luteal phase support with decapeptyl improves pregnancy outcomes in intracytoplasmic sperm injection with higher basal follicle-stimulating hormone or lower mature oocytes. Journal of the Chinese Medical Association 77:10, pages 524-530.
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Kuan-Hao Tsui, Li-Te Lin & Peng-Hui Wang. (2014) Luteal phase support with gonadotropin-releasing hormone agonist. Journal of the Chinese Medical Association 77:10, pages 505-507.
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Yu Li, Ping Pan, Xiaoli Chen, Lin Li, Yi Li & Dongzi Yang. (2013) Granulocyte Colony-Stimulating Factor Administration for Infertile Women With Thin Endometrium in Frozen Embryo Transfer Program. Reproductive Sciences 21:3, pages 381-385.
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C. Coughlan, W. Ledger, Q. Wang, Fenghua Liu, Aygul Demirol, Timur Gurgan, R. Cutting, K. Ong, H. Sallam & T.C. Li. (2014) Recurrent implantation failure: definition and management. Reproductive BioMedicine Online 28:1, pages 14-38.
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Fernando Bonilla-Musoles, Francisco Raga, Newton G. Osborne, Juan Carlos Castillo & Francisco BonillaJrJr. (2013) Endometrial Receptivity. Ultrasound Quarterly 29:1, pages 3-20.
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Dominique de Ziegler, Isabelle Streuli, Vanessa Gayet, Usama Bajouh, Juliane Berdah & Charles Chapron. 2012. Textbook of Assisted Reproductive Techniques, Volume Two: Clinical Perspectives. Textbook of Assisted Reproductive Techniques, Volume Two: Clinical Perspectives 153 161 .
Abha Majumdar & DattaprasadB Inamdar. (2012) Evaluation of the impact of gonadotropin-releasing hormone agonist as an adjuvant in luteal-phase support on IVF outcome. Journal of Human Reproductive Sciences 5:3, pages 279.
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Madafeitom MA Bodombossou-Djobo, Chengyu Zheng, Shaoqing Chen & Dongzi Yang. (2011) Neuromuscular electrical stimulation and biofeedback therapy may improve endometrial growth for patients with thin endometrium during frozen-thawed embryo transfer: A preliminary report. Reproductive Biology and Endocrinology 9:1.
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José Bellver, Elena Labarta, Ernesto Bosch, Marco A.B. Melo, Carmina Vidal, José Remohí & Antonio Pellicer. (2010) GnRH agonist administration at the time of implantation does not improve pregnancy outcome in intrauterine insemination cycles: a randomized controlled trial. Fertility and Sterility 94:3, pages 1065-1071.
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