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Drug Evaluation

Methylphenidate HCL for the treatment of ADHD in children and adolescents

Pages 1171-1178 | Received 09 Feb 2016, Accepted 20 Apr 2016, Published online: 20 May 2016

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Ann C. Childress, Marina Komolova & F. Randy Sallee. (2019) An update on the pharmacokinetic considerations in the treatment of ADHD with long-acting methylphenidate and amphetamine formulations. Expert Opinion on Drug Metabolism & Toxicology 15:11, pages 937-974.
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Articles from other publishers (17)

Ann C. Childress. (2022) Stimulants. Child and Adolescent Psychiatric Clinics of North America 31:3, pages 373-392.
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M.S. Kahrizi, K. Ghanbari Mardasi, P. Ghanbari Merdasi & M. Assareh. (2022) Prevalence of tics among attention deficit hyperactivity disorder children treated with methylphenidate. Neuropsychiatrie de l'Enfance et de l'Adolescence 70:3, pages 117-121.
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Timothy E. Wilens, Stephen V. Faraone, Paul G. Hammerness, Steven R. Pliszka, Cassandra L. Uchida, Norberto J. DeSousa, Floyd R. Sallee, Bev Incledon & Jeffrey H. Newcorn. (2021) Clinically Meaningful Improvements in Early Morning and Late Afternoon/Evening Functional Impairment in Children with ADHD Treated with Delayed-Release and Extended-Release Methylphenidate. Journal of Attention Disorders 26:5, pages 696-705.
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Azmi Nasser, Tesfaye Liranso, Toyin Adewole, Nicholas Fry, Joseph T. Hull, Gregory D. Busse, Fatima Chowdhry, Andrew J. Cutler, Nandita Joshi Jones, Robert L. Findling & Stefan Schwabe. (2021) A Phase 3, Placebo-Controlled Trial of Once-Daily Viloxazine Extended-Release Capsules in Adolescents With Attention-Deficit/Hyperactivity Disorder. Journal of Clinical Psychopharmacology 41:4, pages 370-380.
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Greg W. Mattingly, Joshua Wilson, Leticia Ugarte & Paul Glaser. (2020) Individualization of attention-deficit/hyperactivity disorder treatment: pharmacotherapy considerations by age and co-occurring conditions. CNS Spectrums 26:3, pages 202-221.
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Frank A. LópezStephen V. FaraoneJeffrey H. NewcornHelen A. DollStephanie RhotenHannah B. LewisTayyaba F. KhanNorberto J. DeSousaFloyd R. SalleeBev Incledon. (2021) Effect of Delayed-Release and Extended-Release Methylphenidate on Caregiver Strain and Validation of Psychometric Properties of the Caregiver Strain Questionnaire: Results from a Phase 3 Trial in Children with Attention-Deficit/Hyperactivity Disorder. Journal of Child and Adolescent Psychopharmacology 31:3, pages 179-186.
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Gregory W. Mattingly & Joel Young. (2021) A clinician’s guide for navigating the world of attention deficit hyperactivity disorder medications. CNS Spectrums 26:2, pages 104-114.
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Ann C. ChildressMatthew N. BramsAndrew J. CutlerGraeme A.E. DonnellySailaja Bhaskar. (2020) Efficacy and Safety of Multilayer, Extended-Release Methylphenidate (PRC-063) in Children 6–12 Years of Age with Attention-Deficit/Hyperactivity Disorder: A Laboratory Classroom Study. Journal of Child and Adolescent Psychopharmacology 30:10, pages 580-589.
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Ann C. Childress, Cassandra L. Uchida, Michelle D. Po, Norberto J. DeSousa & Bev Incledon. (2020) A Post Hoc Comparison of Prior ADHD Medication Dose and Optimized Delayed-release and Extended-release Methylphenidate Dose in a Pivotal Phase III Trial. Clinical Therapeutics 42:12, pages 2332-2340.
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Roberto Gomeni, Marina Komolova, Bev Incledon & Stephen V. Faraone. (2020) Model-Based Approach for Establishing the Predicted Clinical Response of a Delayed-Release and Extended-Release Methylphenidate for the Treatment of Attention-Deficit/Hyperactivity Disorder. Journal of Clinical Psychopharmacology 40:4, pages 350-358.
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Ann C. ChildressAndrew J. CutlerAndrea MarraffinoMary Ann McDonnellJohn M. TurnbowMatthew BramsNorberto J. DeSousaBev IncledonFloyd R. SalleeSharon B. Wigal. (2020) A Randomized, Double-Blind, Placebo-Controlled Study of HLD200, a Delayed-Release and Extended-Release Methylphenidate, in Children with Attention-Deficit/Hyperactivity Disorder: An Evaluation of Safety and Efficacy Throughout the Day and Across Settings. Journal of Child and Adolescent Psychopharmacology 30:1, pages 2-14.
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Riki Taitelbaum-Swead, Zvi Kozol & Leah Fostick. (2019) Listening Effort Among Adults With and Without Attention-Deficit/Hyperactivity Disorder. Journal of Speech, Language, and Hearing Research 62:12, pages 4554-4563.
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Tao LiuJogarao V.S. GobburuMichelle D. PoAngus McLeanNorberto J. DeSousaFloyd R. SalleeBev Incledon. (2019) Pharmacokinetics of HLD200, a Delayed-Release and Extended-Release Methylphenidate: Evaluation of Dose Proportionality, Food Effect, Multiple-Dose Modeling, and Comparative Bioavailability with Immediate-Release Methylphenidate in Healthy Adults. Journal of Child and Adolescent Psychopharmacology 29:3, pages 181-191.
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Ann ChildressShailly MehrotraJogarao GobburuAngus McLeanNorberto J. DeSousaBev Incledon. (2018) Single-Dose Pharmacokinetics of HLD200, a Delayed-Release and Extended-Release Methylphenidate Formulation, in Healthy Adults and in Adolescents and Children with Attention-Deficit/Hyperactivity Disorder. Journal of Child and Adolescent Psychopharmacology 28:1, pages 10-18.
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Ann Childress, Jeffrey G. Stark, Russ McMahen, Dorothy Engelking & Carolyn Sikes. (2018) A Comparison of the Pharmacokinetics of Methylphenidate Extended-Release Orally Disintegrating Tablets With a Reference Extended-Release Formulation of Methylphenidate in Healthy Adults. Clinical Pharmacology in Drug Development 7:2, pages 151-159.
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Peter Greven, Vanja Sikirica, Yaozhu J. Chen, Tammy G. Curtice & Charles Makin. (2016) Comparative treatment patterns, healthcare resource utilization and costs of atomoxetine and long-acting methylphenidate among children and adolescents with attention-deficit/hyperactivity disorder in Germany. The European Journal of Health Economics 18:7, pages 893-904.
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Steven R. PliszkaTimothy E. WilensSamantha BostromValerie K. ArnoldAndrea MarraffinoAndrew J. CutlerFrank A. LópezNorberto J. DeSousaFloyd R. SalleeBev IncledonJeffrey H. Newcorn. (2017) Efficacy and Safety of HLD200, Delayed-Release and Extended-Release Methylphenidate, in Children with Attention-Deficit/Hyperactivity Disorder. Journal of Child and Adolescent Psychopharmacology 27:6, pages 474-482.
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