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Drug Evaluation

Obeticholic acid for the treatment of primary biliary cholangitis

&
Pages 1809-1815 | Received 11 Mar 2016, Accepted 26 Jul 2016, Published online: 09 Aug 2016

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Junhui Yu, Kui Yang, Jianbao Zheng, Wei Zhao & Xuejun Sun. (2020) Synergistic tumor inhibition of colon cancer cells by nitazoxanide and obeticholic acid, a farnesoid X receptor ligand. Cancer Gene Therapy 28:6, pages 590-601.
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I. M. Iljinsky & O. M. Tsirulnikova. (2021) Primary biliary cholangitis. Russian Journal of Transplantology and Artificial Organs 23:1, pages 162-170.
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Raquel T Yokoda & Eduardo A Rodriguez. (2020) Review: Pathogenesis of cholestatic liver diseases. World Journal of Hepatology 12:8, pages 423-435.
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Zobair M. Younossi, Maria Stepanova, Pegah Golabi, Robert S. Epstein, Marcie E. Strauss, Fatema Nader & Andrei Racila. (2019) Factors Associated With Potential Progressive Course of Primary Biliary Cholangitis. Journal of Clinical Gastroenterology 53:9, pages 693-698.
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Omer Shahab, Mehmet Sayiner, James Paik, Sean Felix, Pegah Golabi & Zobair M. Younossi. (2019) Burden of Primary Biliary Cholangitis Among Inpatient Population in the United States. Hepatology Communications 3:3, pages 356-364.
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Nahum Méndez-Sánchez. (2018) Management of primary biliary cholangitis: the importance to identify patients' non-responders to standard treatment. Minerva Medica 109:6.
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Xiao-Long He, Li-Ting Wang, Xiang-Zhong Gu, Jie-Xin Xiao & Wen-Wei Qiu. (2018) A facile synthesis of ursodeoxycholic acid and obeticholic acid from cholic acid. Steroids 140, pages 173-178.
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Peter HegyiJozsef MaléthJulian R. WaltersAlan F. HofmannStephen J. Keely. (2018) Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease. Physiological Reviews 98:4, pages 1983-2023.
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Kuo Gai, Yu Huang, Baomin Liu & Yinsheng Zhang. (2018) Synthesis of obeticholic acid, a farnesoid X receptor agonist, and its major metabolites labeled with deuterium. Journal of Labelled Compounds and Radiopharmaceuticals 61:10, pages 799-804.
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Michal Douša, Markéta Slavíková, Tomáš Kubelka, Josef Černý, Petr Gibala & Josef Zezula. (2018) HPLC/UV/MS method application for the separation of obeticholic acid and its related compounds in development process and quality control. Journal of Pharmaceutical and Biomedical Analysis 149, pages 214-224.
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Juan Pablo Arab, Francisco Barrera & Marco Arrese. (2017) Bile Acids and Portal Hypertension. Annals of Hepatology 16, pages S83-S86.
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Atsushi Tanaka, Patrick S.C. Leung, Howard A. Young & M. Eric Gershwin. (2017) Toward solving the etiological mystery of primary biliary cholangitis. Hepatology Communications 1:4, pages 275-287.
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M.G. Fernandez-Barrena, M. Barcena-Varela & J.M. Banales. (2017) New evidence supporting the biliary bicarbonate umbrella theory. Clinics and Research in Hepatology and Gastroenterology 41:2, pages 126-128.
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Lingling Luo, Yin Li, Dongshan Wang, Yuanyuan Zhao, Yahui Wang, Fei Li, Jinan Fang, Hui Chen, Shengjie Fan & Cheng Huang. (2017) Ginkgolide B lowers body weight and ameliorates hepatic steatosis in high-fat diet-induced obese mice correlated with pregnane X receptor activation. RSC Advances 7:60, pages 37858-37866.
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