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Expert Opinion on Pharmacotherapy Volume 17, 2016 - Issue 14
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Review

Systemic treatment for advanced hepatocellular carcinoma: the search of new agents to join sorafenib in the effective therapeutic armamentarium

Andrea Ribeiro de SouzaBarcelona Clinic Liver Cancer (BCLC), Liver Unit, Center of Biomedical Research in Hepatic and Digestive Diseases of the Ministry of Science and Innovation (CIBERehd), Hospital Clínic- IDIBAPS; University of Barcelona, Barcelona, SpainView further author information
,
Maria ReigBarcelona Clinic Liver Cancer (BCLC), Liver Unit, Center of Biomedical Research in Hepatic and Digestive Diseases of the Ministry of Science and Innovation (CIBERehd), Hospital Clínic- IDIBAPS; University of Barcelona, Barcelona, SpainView further author information
&
Jordi BruixBarcelona Clinic Liver Cancer (BCLC), Liver Unit, Center of Biomedical Research in Hepatic and Digestive Diseases of the Ministry of Science and Innovation (CIBERehd), Hospital Clínic- IDIBAPS; University of Barcelona, Barcelona, SpainCorrespondence[email protected]
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Pages 1923-1936 | Received 24 May 2016, Accepted 11 Aug 2016, Published online: 19 Sep 2016

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S. Karakuş, F. Tok, S. Türk, E. Salva, G. Tatar, T. Taskın-Tok & B. Kocyigit-Kaymakcıoglu. (2018) Synthesis, anticancer activity and ADMET studies of N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-[(3-substituted)ureido/thioureido] benzenesulfonamide derivatives. Phosphorus, Sulfur, and Silicon and the Related Elements 193:8, pages 528-534.
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Sinem Yilmaz, Fatih Tok, Esra Atalay-Sahar, Bedia Kocyigit-Kaymakcioglu & Petek Ballar-Kırmızıbayrak. (2022) Induction of Divergent Cell Death Pathways by Urea and Carbohydrazide Derivatives. Anti-Cancer Agents in Medicinal Chemistry 22:9, pages 1761-1768.
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Heba Mohamed, Mohamed AL-Ghareeb & Raghda Abd-Allah. (2022) Pharmacological Evaluation of Novel 1,2,4-triazine Derivatives Containing Thiazole Ring against Hepatocellular Carcinoma. Current Bioactive Compounds 18:2.
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Adam Bieniek, Marek Wiśniewski, Joanna Czarnecka, Jędrzej Wierzbicki, Marcin Ziętek, Maciej Nowacki, Dariusz Grzanka, Tomasz Kloskowski & Katarzyna Roszek. (2021) Porphyrin Based 2D-MOF Structures as Dual-Kinetic Sorafenib Nanocarriers for Hepatoma Treatment. International Journal of Molecular Sciences 22:20, pages 11161.
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Antoni Sureda, Miquel Martorell, Xavier Capó, Margalida Monserrat-Mesquida, Maria Magdalena Quetglas-Llabrés, Mahsa Rasekhian, Seyed M. Nabavi & Silvia Tejada. (2021) Antitumor Effects of Triterpenes in Hepatocellular Carcinoma. Current Medicinal Chemistry 28:13, pages 2465-2484.
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Yi-Xian Guo. (2020) Hepatocellular carcinoma with right atrial tumor thrombus. Zeitschrift für Gastroenterologie 59:02, pages 153-161.
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Chunying Hou, Dongqing Guo, Xue Yu, Shuyan Wang & Tianhua Liu. (2020) TMT-based proteomics analysis of the anti-hepatocellular carcinoma effect of combined dihydroartemisinin and sorafenib. Biomedicine & Pharmacotherapy 126, pages 109862.
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Matteo Virdis, Michela Monteleone, Michele Droz dit Busset & Vincenzo Mazzaferro. 2018. Clinical Applications of Nuclear Medicine Targeted Therapy. Clinical Applications of Nuclear Medicine Targeted Therapy 95 105 .
Bo Du, Peng Zhang, Zhiming Tan & Jifan Xu. (2017) MiR-1202 suppresses hepatocellular carcinoma cells migration and invasion by targeting cyclin dependent kinase 14. Biomedicine & Pharmacotherapy 96, pages 1246-1252.
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Jordi Bruix, Ann-Lii Cheng, Gerold Meinhardt, Keiko Nakajima, Yoriko De Sanctis & Josep Llovet. (2017) Prognostic factors and predictors of sorafenib benefit in patients with hepatocellular carcinoma: Analysis of two phase III studies. Journal of Hepatology 67:5, pages 999-1008.
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A. D?az-Gonz?lez & A. Forner. (2017) Hepatocellular carcinoma: Therapeutic strategy in 2017Carcinome h?patocellulaire: strat?gie th?rapeutique en 2017. Oncologie 19:5-6, pages 177-183.
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Junjie Lan, Ning Wang, Lan Huang, Yazhou Liu, Xiaopan Ma, Huayong Lou, Chao Chen, Yibin Feng & Weidong Pan. (2017) Design and synthesis of novel tetrandrine derivatives as potential anti-tumor agents against human hepatocellular carcinoma. European Journal of Medicinal Chemistry 127, pages 554-566.
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Alessandro Cucchetti, Fabio Piscaglia, Antonio Daniele Pinna, Benjamin Djulbegovic, Federico Mazzotti & Luigi Bolondi. (2017) Efficacy and Safety of Systemic Therapies for Advanced Hepatocellular Carcinoma: A Network Meta-Analysis of Phase III Trials. Liver Cancer 6:4, pages 337-348.
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