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Expert Opinion on Pharmacotherapy Volume 20, 2019 - Issue 16
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Review

Systemic therapy for the treatment of endometrial cancer

Manuela NeriDepartment of Obstetrics and Gynaecology, Department of Surgical Sciences, University of Cagliari, Monserrato, Italy;Maternal Child Department, University Hospital of Cagliari, Monserrato, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-4731-8230View further author information
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Michele PeirettiDepartment of Obstetrics and Gynaecology, Department of Surgical Sciences, University of Cagliari, Monserrato, Italy;Maternal Child Department, University Hospital of Cagliari, Monserrato, ItalyORCID Iconhttps://orcid.org/0000-0001-9758-4257View further author information
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Gian Benedetto MelisDepartment of Obstetrics and Gynaecology, Department of Surgical Sciences, University of Cagliari, Monserrato, Italy;Maternal Child Department, University Hospital of Cagliari, Monserrato, ItalyORCID Iconhttps://orcid.org/0000-0002-2260-9277View further author information
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Bruno PirasDepartment of Obstetrics and Gynaecology, Department of Surgical Sciences, University of Cagliari, Monserrato, Italy;Maternal Child Department, University Hospital of Cagliari, Monserrato, ItalyORCID Iconhttps://orcid.org/0000-0001-5609-9925View further author information
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Valerio VallerinoDepartment of Obstetrics and Gynaecology, Department of Surgical Sciences, University of Cagliari, Monserrato, Italy;Maternal Child Department, University Hospital of Cagliari, Monserrato, ItalyORCID Iconhttps://orcid.org/0000-0002-7933-9757View further author information
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Anna Maria PaolettiDepartment of Obstetrics and Gynaecology, Department of Surgical Sciences, University of Cagliari, Monserrato, Italy;Maternal Child Department, University Hospital of Cagliari, Monserrato, ItalyORCID Iconhttps://orcid.org/0000-0001-6644-0509View further author information
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Clelia MadedduDepartment of Medical Oncology, Department of Internal Medicine, University of Cagliari, Monserrato, ItalyORCID Iconhttps://orcid.org/0000-0001-8940-6987View further author information
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Mario ScartozziDepartment of Medical Oncology, Department of Internal Medicine, University of Cagliari, Monserrato, ItalyORCID Iconhttps://orcid.org/0000-0001-5977-5546View further author information
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Valerio MaisDepartment of Obstetrics and Gynaecology, Department of Surgical Sciences, University of Cagliari, Monserrato, Italy;Maternal Child Department, University Hospital of Cagliari, Monserrato, ItalyORCID Iconhttps://orcid.org/0000-0002-1362-9102View further author information
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Pages 2019-2032 | Received 23 Feb 2019, Accepted 08 Aug 2019, Published online: 26 Aug 2019

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Yuwei Li, Ziling Yang, Mengyao Zeng, Ying Wang, Xin Chen, Shibo Li, Xiaotong Zhao & Yuhui Sun. (2023) Circular RNA differential expression profiles and bioinformatics analysis of hsa_circRNA_079422 in human endometrial carcinoma. Journal of Obstetrics and Gynaecology 43:2.
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Keishi Akada, Noriyuki Koyama, Takuma Miura, Eiji Fukunaga, Yuji Miura, Ken Aoshima & Keiichi Fujiwara. (2021) Real-world database analysis of the characteristics and treatment patterns of patients with endometrial cancer in Japan. Current Medical Research and Opinion 37:7, pages 1171-1178.
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Articles from other publishers (25)

Chase William Morrison, Kayvon Nick Sanjasaz, Saul David Nathanson, Supriya Raina-Hukku, David Matthew Pinkney & Alexis Anna Davenport. (2023) Dedifferentiated endometrial carcinoma metastasis to axillary lymph node: a case report. Journal of Medical Case Reports 17:1.
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Jessica Satei, Ariana N Afrakhteh & Kim Abbegail T Aldecoa. (2023) Endometrial Adenocarcinoma in Young Women: A Case Report and Review of Literature. Cureus.
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Sidra Khan, Noor A. Lokman, Martin K. Oehler, Carmela Ricciardelli & Andrea J. Yool. (2023) Reducing the Invasiveness of Low- and High-Grade Endometrial Cancers in Both Primary Human Cancer Biopsies and Cell Lines by the Inhibition of Aquaporin-1 Channels. Cancers 15:18, pages 4507.
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A. Yu. Goryainova, M. G. Leonov, R. A. Murashko, O. S. Tsirulnikova & O. Yu. Chukhrai. (2023) Organization clinical decision-making programs in the local practice of the region: problematic issues that determine the choice of therapy in the progression of endometrial cancer. Meditsinskiy sovet = Medical Council:11, pages 142-149.
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Wan Shu, Ziwei Wang, Wei Zhang, Jun Zhang, Rong Zhao, Zhicheng Yu, Kejun Dong & Hongbo Wang. (2023) Identification of EMT-associated LncRNA Signature for Predicting the Prognosis of Patients with Endometrial Cancer. Combinatorial Chemistry & High Throughput Screening 26:8, pages 1488-1502.
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Wenwen Zhang, Meihua Liu, Yurou Ji, Dake Yu, Chuanrui Ma, Jianguo Zhao & Pengpeng Qu. (2023) Tanshinone IIA inhibits endometrial carcinoma growth through the MAPK/ERK/TRIB3 pathway. Archives of Biochemistry and Biophysics 743, pages 109655.
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Wenxue Li, Yujing Qin, Xiujuan Chen & Xiaolei Wang. (2023) Mining of clinical and prognosis related genes in the tumor microenvironment of endometrial cancer: A field synopsis of observational study. Medicine 102:25, pages e34047.
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Rohit R Doke, Aditi R Lende, Shweta S Mule, Mrunal S Mahajan, Pranali Kulawade, Gayatri V Korde & Rutuja B Bhand. (2023) Endometrial cancer: Pathophysiology, diagnosis and management. IP International Journal of Comprehensive and Advanced Pharmacology 8:2, pages 80-85.
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Kang He, Jingze Li, Xuemiao Huang, Weixin Zhao, Kai Wang, Taiwei Wang, Junyu Chen, Zeyu Wang, Jiang Yi, Shuhua Zhao & Lijing Zhao. (2023) KNL1 is a prognostic and diagnostic biomarker related to immune infiltration in patients with uterine corpus endometrial carcinoma. Frontiers in Oncology 13.
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Bingfeng Lu, Xi Chen, Xin Liu, Jingwen Chen, Honglei Qin, Shuo Chen & Yang Zhao. (2022) C/D box small nucleolar RNA SNORD104 promotes endometrial cancer by regulating the 2ʹ-O-methylation of PARP1. Journal of Translational Medicine 20:1.
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Akiko Yamamoto, Takeo Nagashima, Yoshinari Imai, Kensuke Akitsu, Zenta Yamanaka & Hirotaka Nishi. (2022) A case of recurrent endometrial cancer with long‐term complete remission following pembrolizumab‐induced severe i mmune‐related adverse event colitis . Journal of Obstetrics and Gynaecology Research 48:10, pages 2630-2634.
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Bartłomiej Barczyński, Karolina Frąszczak, Iwona Wertel, Ewelina Zakrzewska, Małgorzata Zdunek, Justyna Szumiło & Jan Kotarski. (2022) Immunohistochemical Expression of LHRH Receptor in Different Compartments of Female Genital Tract in Patients With Endometrial Cancer. Applied Immunohistochemistry & Molecular Morphology 30:7, pages 509-516.
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Xiaojuan Li & Yahong Liu. (2022) Hsa_circ_0000437 Inhibits the Development of Endometrial Carcinoma through miR-626/CDKN1B Axis. Protein & Peptide Letters 29:7, pages 611-620.
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Beatriz Villafranca-Magdalena, Carina Masferrer-Ferragutcasas, Carlos Lopez-Gil, Eva Coll-de la Rubia, Marta Rebull, Genis Parra, Ángel García, Armando Reques, Silvia Cabrera, Eva Colas, Antonio Gil-Moreno & Cristian P. Moiola. (2022) Genomic Validation of Endometrial Cancer Patient-Derived Xenograft Models as a Preclinical Tool. International Journal of Molecular Sciences 23:11, pages 6266.
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Cristina Martín-Sabroso, Irene Lozza, Ana Isabel Torres-Suárez & Ana Isabel Fraguas-Sánchez. (2021) Antibody-Antineoplastic Conjugates in Gynecological Malignancies: Current Status and Future Perspectives. Pharmaceutics 13:10, pages 1705.
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M Abtahi, S Gholami & H H Jassim. (2021) High dose rate 192 Ir versus high dose rate 60 Co brachytherapy: an overview of systematic reviews of clinical responses of gynecological cancers from 1984 to 2020 . Biomedical Physics & Engineering Express 7:5, pages 055022.
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Yanqi Dong, Aiqi Yin, Caiqu Xu, Huiping Jiang, Qinghai Wang, Wenjuan Wu & Suiqun Guo. (2021) OLA1 is a potential prognostic molecular biomarker for endometrial cancer and promotes tumor progression. Oncology Letters 22:2.
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Jian Ma, Fan-Fei Kong, Di Yang, Hui Yang, Cuicui Wang, Rong Cong & Xiao-Xin Ma. (2021) lncRNA MIR210HG promotes the progression of endometrial cancer by sponging miR-337-3p/137 via the HMGA2-TGF-β/Wnt pathway. Molecular Therapy - Nucleic Acids 24, pages 905-922.
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Nina Kovacevic. (2021) Surgical treatment and fertility perservation in endometrial cancer. Radiology and Oncology 55:2, pages 144-149.
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Valerio Mais & Michele Peiretti. (2021) Immunohistochemical Markers in Endometrial Cancer. Cancers 13:3, pages 505.
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Sebastjan Merlo, Gregor Vivod, Sonja Bebar, Maša Bošnjak, Maja Čemažar, Gregor Serša, Simona Kranjc Brezar & Nina Kovačević. (2021) Literature Review and Our Experience With Bleomycin-Based Electrochemotherapy for Cutaneous Vulvar Metastases From Endometrial Cancer. Technology in Cancer Research & Treatment 20, pages 153303382110101.
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Jian Ma, Jing-Kai Zhang, Di Yang & Xiao-Xin Ma. (2020) Identification of novel prognosis-related genes in the endometrial cancer immune microenvironment. Aging 12:21, pages 22152-22173.
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Yusuke Toyohara, Kenbun Sone, Haruka Nishida, Ayumi Taguchi, Yuichiro Miyamoto, Michihiro Tanikawa, Mayuyo Mori, Tetsushi Tsuruga, Yoko Matsumoto, Katsutoshi Oda, Yutaka Osuga & Tomoyuki Fujii. (2020) Desensitization strategy for hypersensitivity reactions to carboplatin in five patients with gynecological cancer. Journal of Obstetrics and Gynaecology Research 46:11, pages 2298-2304.
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Ling Liu, Zhi‐Ying Yu, Tan‐Tan Yu, Shi‐Hong Cui, Li Yang, Hui Chang, Yan‐Hong Qu, Xiao‐Feng Lv, Xiao‐An Zhang & Chen‐Chen Ren. (2020) A Slug‐dependent mechanism is responsible for tumor suppression of p53‐stabilizing compound CP‐31398 in p53‐mutated endometrial carcinoma. Journal of Cellular Physiology 235:11, pages 8768-8778.
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Liyan Xu, Yafen Qiu, Ling Feng, Li Zhou, Xufeng Chen & Dongqi Yu. (2020) Correlation between single nucleotide polymorphisms of DACH1 gene microRNA binding site and susceptibility of patients with endometrial cancer. Medicine 99:25, pages e20793.
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