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Expert Opinion on Pharmacotherapy Volume 21, 2020 - Issue 18
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Drug Evaluation

Cenobamate for the treatment of focal epilepsies

Adam Strzelczyka Epilepsy Center Frankfurt Rhine-Main, Center of Neurology and Neurosurgery, Goethe-University Frankfurt, Frankfurt Am Main, Germany;b LOEWE Center for Personalized Translational Epilepsy Research (Cepter), Goethe-University Frankfurt, Frankfurt Am Main, GermanyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6288-9915View further author information
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Catrin Manna Epilepsy Center Frankfurt Rhine-Main, Center of Neurology and Neurosurgery, Goethe-University Frankfurt, Frankfurt Am Main, Germany;b LOEWE Center for Personalized Translational Epilepsy Research (Cepter), Goethe-University Frankfurt, Frankfurt Am Main, GermanyView further author information
,
Laurent M. Willemsa Epilepsy Center Frankfurt Rhine-Main, Center of Neurology and Neurosurgery, Goethe-University Frankfurt, Frankfurt Am Main, Germany;b LOEWE Center for Personalized Translational Epilepsy Research (Cepter), Goethe-University Frankfurt, Frankfurt Am Main, GermanyORCID Iconhttps://orcid.org/0000-0001-8226-1674View further author information
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Felix Rosenowa Epilepsy Center Frankfurt Rhine-Main, Center of Neurology and Neurosurgery, Goethe-University Frankfurt, Frankfurt Am Main, Germany;b LOEWE Center for Personalized Translational Epilepsy Research (Cepter), Goethe-University Frankfurt, Frankfurt Am Main, GermanyORCID Iconhttps://orcid.org/0000-0002-3989-7471View further author information
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Sebastian Bauera Epilepsy Center Frankfurt Rhine-Main, Center of Neurology and Neurosurgery, Goethe-University Frankfurt, Frankfurt Am Main, Germany;b LOEWE Center for Personalized Translational Epilepsy Research (Cepter), Goethe-University Frankfurt, Frankfurt Am Main, GermanyORCID Iconhttps://orcid.org/0000-0001-7571-8496View further author information
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Pages 2215-2223 | Received 03 Jul 2020, Accepted 28 Jul 2020, Published online: 19 Aug 2020

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Gaetano Zaccara, Simona Lattanzi, Antonio Leo & Emilio Russo. (2021) Critical Appraisal of Cenobamate as Adjunctive Treatment of Focal Seizures in Adults. Neuropsychiatric Disease and Treatment 17, pages 3447-3457.
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James W. Wheless. (2020) Adjunctive cenobamate for the treatment of focal onset seizures in adults with epilepsy: a critical review. Expert Review of Neurotherapeutics 20:11, pages 1085-1098.
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Articles from other publishers (11)

Jamir Pitton Rissardo & Ana Letícia Fornari Caprara. (2023) Cenobamate (YKP3089) and Drug-Resistant Epilepsy: A Review of the Literature. Medicina 59:8, pages 1389.
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Anna-Lena Friedo, Benedikt Greshake, Konstantin L. Makridis & Hans-Beatus Straub. (2023) Cenobamate significantly improves seizure control in intellectually disabled patients with drug-resistant epilepsy and allows drug load reduction. Frontiers in Neurology 14.
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Maria Antonietta Barbieri, Emilio Perucca, Edoardo Spina, Paola Rota & Valentina Franco. (2023) Cenobamate: A Review of its Pharmacological Properties, Clinical Efficacy and Tolerability Profile in the Treatment of Epilepsy. CNS & Neurological Disorders - Drug Targets 22:3, pages 394-403.
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Chao Wu, Baode Ma, Gen-Qiang Chen & Xumu Zhang. (2022) Highly efficient and enantioselective synthesis of β-heteroaryl amino alcohols via Ru-catalyzed asymmetric hydrogenation . Chemical Communications 58:91, pages 12696-12699.
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Adam Strzelczyk & Susanne Schubert-Bast. (2022) Psychobehavioural and Cognitive Adverse Events of Anti-Seizure Medications for the Treatment of Developmental and Epileptic Encephalopathies. CNS Drugs 36:10, pages 1079-1111.
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Eunsol Yang, Jung Sunwoo, Ki Young Huh, Yu Kyong Kim, SeungHwan Lee, In‐Jin Jang & Kyung‐Sang Yu. (2021) Pharmacokinetics and safety of cenobamate, a novel antiseizure medication, in healthy Japanese, and an ethnic comparison with healthy non‐Japanese. Clinical and Translational Science 15:2, pages 490-500.
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Laurent M. Willems, Felix Rosenow, Susanne Schubert-Bast, Gerhard Kurlemann, Johann Philipp Zöllner, Thomas Bast, Astrid Bertsche, Ulrich Bettendorf, Daniel Ebrahimi-Fakhari, Janina Grau, Andreas Hahn, Hans Hartmann, Christoph Hertzberg, Frauke Hornemann, Ilka Immisch, Julia Jacobs, Karl Martin Klein, Kerstin A. Klotz, Gerhard Kluger, Susanne Knake, Markus Knuf, Klaus Marquard, Thomas Mayer, Sascha Meyer, Hiltrud Muhle, Karen Müller-Schlüter, Felix von Podewils, Susanne Ruf, Matthias Sauter, Hannah Schäfer, Jan-Ulrich Schlump, Steffen Syrbe, Charlotte Thiels, Regina Trollmann, Adelheid Wiemer-Kruel, Bernd Wilken, Bianca Zukunft & Adam Strzelczyk. (2021) Efficacy, Retention and Tolerability of Everolimus in Patients with Tuberous Sclerosis Complex: A Survey-Based Study on Patients’ Perspectives. CNS Drugs 35:10, pages 1107-1122.
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Nicola Specchio, Nicola Pietrafusa & Federico Vigevano. (2021) Is Cenobamate the Breakthrough We Have Been Wishing for?. International Journal of Molecular Sciences 22:17, pages 9339.
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Megan Maroney & Marija Markovic. 2021. 99 121 .
Adam Strzelczyk & Susanne Schubert-Bast. (2021) Expanding the Treatment Landscape for Lennox-Gastaut Syndrome: Current and Future Strategies. CNS Drugs 35:1, pages 61-83.
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Ana Matošević & Anita Bosak. (2020) Carbamate group as structural motif in drugs: a review of carbamate derivatives used as therapeutic agents. Archives of Industrial Hygiene and Toxicology 71:4, pages 285-299.
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