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Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders Volume 1, 2000 - Issue 3
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Research Article

Oral administration of creatine monohydrate retards progression of motor neuron disease in the wobbler mouse

Ken Ikeda Fourth Department of Internal Medicine Toho University Ohashi Hospital Tokyo, Japan
,
Yasuo Iwasaki Fourth Department of Internal Medicine Toho University Ohashi Hospital Tokyo, Japan
&
Masao Kinoshita Fourth Department of Internal Medicine Toho University Ohashi Hospital Tokyo, Japan
Pages 207-212 | Published online: 10 Jul 2009

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Richard Kones. (2010) Mitochondrial therapy for Parkinson’s disease: Neuroprotective pharmaconutrition may be disease-modifying. Clinical Pharmacology: Advances and Applications 2, pages 185-198.
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Steven K Baker & Mark A Tarnopolsky. (2003) Targeting cellular energy production in neurological disorders. Expert Opinion on Investigational Drugs 12:10, pages 1655-1679.
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Articles from other publishers (19)

Komal Panchal & Anand Krishna Tiwari. (2019) Mitochondrial dynamics, a key executioner in neurodegenerative diseases. Mitochondrion 47, pages 151-173.
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Ken Ikeda & Yasuo Iwasaki. (2015) Edaravone, a Free Radical Scavenger, Delayed Symptomatic and Pathological Progression of Motor Neuron Disease in the Wobbler Mouse. PLOS ONE 10:10, pages e0140316.
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Ken Ikeda, Yasuo Iwasaki & Ryuji Kaji. (2015) Neuroprotective effect of ultra-high dose methylcobalamin in wobbler mouse model of amyotrophic lateral sclerosis. Journal of the Neurological Sciences 354:1-2, pages 70-74.
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Jean-Claude Desport, Pierre Jésus, Philippe Fayemendy & Lucile Pouchard. (2014) Activité physique lors de la sclérose latérale amyotrophique. Nutrition Clinique et Métabolisme 28:4, pages 321-326.
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Clare E. Turner & Nicholas Gant. 2014. Magnetic Resonance Spectroscopy. Magnetic Resonance Spectroscopy 91 103 .
Jakob Maximilian Moser, Paolo Bigini & Thomas Schmitt-John. (2013) The wobbler mouse, an ALS animal model. Molecular Genetics and Genomics 288:5-6, pages 207-229.
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Jonathan D. Glass. (2012) New drugs for ALS: How do we get there?. Experimental Neurology 233:1, pages 112-117.
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Richard Kones. (2010) Parkinson’s Disease: Mitochondrial Molecular Pathology, Inflammation, Statins, and Therapeutic Neuroprotective Nutrition. Nutrition in Clinical Practice 25:4, pages 371-389.
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Lichuan Yang, Noel Y. Calingasan, Elizabeth J. Wille, Kerry Cormier, Karen Smith, Robert J. Ferrante & M. Flint Beal. (2009) Combination therapy with Coenzyme Q 10 and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s Diseases . Journal of Neurochemistry 109:5, pages 1427-1439.
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John T. BrosnanMargaret E. Brosnan. (2007) Creatine: Endogenous Metabolite, Dietary, and Therapeutic Supplement. Annual Review of Nutrition 27:1, pages 241-261.
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Autumn M. Klein & Robert J. Ferrante. 2007. Creatine and Creatine Kinase in Health and Disease. Creatine and Creatine Kinase in Health and Disease 205 243 .
Barbara Santoro, Paolo Bigini, Giovanna Levandis, Vincenzo Nobile, Marco Biggiogera, Francesca Botti, Tiziana Mennini & Daniela Curti. (2004) Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease. Neurobiology of Disease 17:2, pages 349-357.
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Peter Klivenyi, Noel Y Calingasan, Anatoly Starkov, Irina G Stavrovskaya, Bruce S Kristal, Lichuan Yang, Bé Wieringa & M.Flint Beal. (2004) Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase. Neurobiology of Disease 15:3, pages 610-617.
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. 2004. Management of Patients with Neuromuscular Disease. Management of Patients with Neuromuscular Disease 355 397 .
R.J Snow, J Turnbull, S da Silva, F Jiang & M.A Tarnopolsky. (2003) Creatine supplementation and riluzole treatment provide similar beneficial effects in copper, zinc superoxide dismutase (G93A) transgenic mice. Neuroscience 119:3, pages 661-667.
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Martin R. Turner & P. Nigel Leigh. 2003. Motor Neuron Disorders. Motor Neuron Disorders 497 544 .
Clare Wood-Allum & Pamela J. Shaw. 2003. Motor Neuron Disorders. Motor Neuron Disorders 285 313 .
Markus Wyss & Andreas Schulze. (2002) Health implications of creatine: can oral creatine supplementation protect against neurological and atherosclerotic disease?. Neuroscience 112:2, pages 243-260.
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John M. Lawler, William S. Barnes, Gaoyao Wu, Wook Song & Scott Demaree. (2002) Direct Antioxidant Properties of Creatine. Biochemical and Biophysical Research Communications 290:1, pages 47-52.
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