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Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders Volume 4, 2003 - Issue 1
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Original Research

Can we eliminate placebo in ALS clinical trials?

WW Bryan Department of Neurology, University of Texas Southwestern Medical School, Dallas, Texas, USA
,
RJ Hoagland Syntex‐Synergen Neuroscience Joint Venture, USA
,
J Murphy Department of Preventive Medicine and Biometrics, University of Colorado Health Sciences Center, Denver, Colorado, USA
,
C Armon Department of Neurology, Loma Linda University School of Medicine, Loma Linda, California, USA
,
RJ Barohn Department of Neurology, California Pacific Medical Center, Forbes Norris MDA/ALS Center, San Francisco, California, USA
,
JC Goodpasture Department of Neurology, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA
,
RG Miller Department of Neurology, University of Utah School of Medicine, Salt Lake City, Utah, USA
,
GJ Parry Department of Neurology, University of Kentucky, Lexington, Kentucky, USA
,
JH Petajan The participants and their institutions are listed in the Appendix at the end of this article.
,
MA Ross Department of Neurology, University of Texas Southwestern Medical School, Dallas, Texas, USA
,
SC Stromatt Syntex‐Synergen Neuroscience Joint Venture, USA
& the rhCNTF ALS Study Group show all
Pages 11-15 | Received 08 May 2002, Accepted 06 Dec 2002, Published online: 10 Jul 2009

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Ettore Beghi, Adriano Chiò, Philippe Couratier, Jesùs Esteban, Orla Hardiman, Giancarlo Logroscino, Andrea Millul, Douglas Mitchell, Pierre-Marie Preux, Elisabetta Pupillo, Zorica Stevic, Robert Swingler, Bryan J. Traynor, Leonard H. Van den Berg, Jan H. Veldink & Stefano Zoccolella. (2011) The epidemiology and treatment of ALS: Focus on the heterogeneity of the disease and critical appraisal of therapeutic trials. Amyotrophic Lateral Sclerosis 12:1, pages 1-10.
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Adriano Chiò, Giancarlo Logroscino, Orla Hardiman, Robert Swingler, Douglas Mitchell, Ettore Beghi, Bryan G. Traynor & On Behalf of the Eurals Consortium. (2009) Prognostic factors in ALS: A critical review. Amyotrophic Lateral Sclerosis 10:5-6, pages 310-323.
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Robert K. Yin, R. James Schmidt & Frank Besag. (2006) Aggregating Student Achievement Trends Across States With Different Tests: Using Standardized Slopes as Effect Sizes. Peabody Journal of Education 81:2, pages 47-61.
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Articles from other publishers (9)

B. Jane Distad & Michael D. Weiss. (2019) Edaravone for amyotrophic lateral sclerosis: More evidence for long‐term benefit. Muscle & Nerve 61:2, pages 129-130.
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Marlena Wosiski-Kuhn, Miles S. Lyon, James Caress & Carol Milligan. (2019) Inflammation, immunity, and amyotrophic lateral sclerosis: II. immune-modulating therapies. Muscle & Nerve 59:1, pages 23-33.
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Silvia Toni, Riccardo Morandi, Marcello Busacchi, Lucia Tardini, Luciano Merlini, Nino Carlo Battistini & Massimo Pellegrini. (2014) Nutritional Status Evaluation in Patients Affected by Bethlem Myopathy and Ullrich Congenital Muscular Dystrophy. Frontiers in Aging Neuroscience 6.
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Katalin Scherer & Richard S. Bedlack. (2012) Diaphragm pacing in amyotrophic lateral sclerosis: A literature review. Muscle & Nerve 46:1, pages 1-8.
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Seward B. Rutkove, Hui Zhang, David A. Schoenfeld, Elizabeth M. Raynor, Jeremy M. Shefner, Merit E. Cudkowicz, Anne B. Chin, Ronald Aaron & Carl A. Shiffman. (2007) Electrical impedance myography to assess outcome in amyotrophic lateral sclerosis clinical trials. Clinical Neurophysiology 118:11, pages 2413-2418.
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Adam Czaplinski, Albert A. Yen, Ericka P. Simpson & Stanley H. Appel. (2006) Predictability of disease progression in amyotrophic lateral sclerosis. Muscle & Nerve 34:6, pages 702-708.
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A. CzaplinskiL. J. HaverkampA. A. YenE. P. SimpsonE. C. LaiS. H. Appel. (2006) The value of database controls in pilot or futility studies in ALS. Neurology 67:10, pages 1827-1832.
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G. LevyP. KaufmannR. BuchsbaumJ. MontesA. BarsdorfR. ArbingV. BattistaX. ZhouH. MitsumotoB. LevinJ.L.P. Thompson. (2006) A two-stage design for a phase II clinical trial of coenzyme Q10 in ALS. Neurology 66:5, pages 660-663.
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William Boissonnault & Jean M. Bryan. (2005) Thrust Joint Manipulation Clinical Education Opportunities for Professional Degree Physical Therapy Students. Journal of Orthopaedic & Sports Physical Therapy 35:7, pages 416-423.
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