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Drug Evaluation

Omalizumab for treating chronic spontaneous urticaria: an expert review on efficacy and safety

Pages 375-385 | Received 12 Oct 2016, Accepted 19 Jan 2017, Published online: 09 Feb 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Tugba Falay Gur, Sevil Savas Erdogan, Vefa Aslı Erdemir & Bilal Doğan. (2020) Effect of omalizumab use on glucose homeostasis in non-diabetic patients with chronic urticaria. Cutaneous and Ocular Toxicology 39:4, pages 348-353.
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Jonathan A. Bernstein, Abhishek Kavati, Michael D. Tharp, Benjamin Ortiz, Karen MacDonald, Kris Denhaerynck & Ivo Abraham. (2018) Effectiveness of omalizumab in adolescent and adult patients with chronic idiopathic/spontaneous urticaria: a systematic review of ‘real-world’ evidence. Expert Opinion on Biological Therapy 18:4, pages 425-448.
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Articles from other publishers (35)

Thomas B. Casale, Ana Maria Gimenez-Arnau, Jonathan A. Bernstein, Michael Holden, Torsten Zuberbier & Marcus Maurer. (2023) Omalizumab for Patients with Chronic Spontaneous Urticaria: A Narrative Review of Current Status. Dermatology and Therapy 13:11, pages 2573-2588.
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Yun-zhou Shi, Shu-guang Yu, Hui Zheng, Qian-hua Zheng, Si-yuan Zhou, Ying Huang, Lei-xiao Zhang, Xian-jun Xiao, Wei Cao & Ying Li. (2023) Acupuncture for Patients with Chronic Spontaneous Urticaria: A Randomized, Sham-Controlled Pilot Trial. Chinese Journal of Integrative Medicine.
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April W. Armstrong, Weily Soong & Jonathan A. Bernstein. (2023) Chronic Spontaneous Urticaria: How to Measure It and the Need to Define Treatment Success. Dermatology and Therapy 13:8, pages 1629-1646.
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J. Barbosa, M. Coelho, A. Brasileiro & A. Giménez-Arnau. (2023) [Artículo traducido]Esteatohepatitis asociada a omalizumab. Actas Dermo-Sifiliográficas 114:7, pages T650-T651.
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J. Barbosa, M. Coelho, A. Brasileiro & A. Giménez-Arnau. (2023) Omalizumab-Associated Steatohepatitis. Actas Dermo-Sifiliográficas 114:7, pages 650-651.
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Reineke Soegiharto, Mehran Alizadeh Aghdam, Andre C. Knulst & Heike Röckmann. (2023) Clinical profile of idiopathic angioedema based on severity and treatment response is independent of the presence of concomitant wheals. JEADV Clinical Practice 2:1, pages 114-121.
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Yun-Zhou Shi, Wei Cao, Chun-Xiao Li, Xian-Jun Xiao, Ying Huang, Lei-Xiao Zhang, Zi-Hao Zou, Si-Jue Chen, Qian Yang, Lu Wang, Ping-Sheng Hao, Zi-Ping Gao & Ying Li. (2022) Acupuncture and Related Therapies for Chronic Urticaria: A Critical Overview of Systematic Reviews. Evidence-Based Complementary and Alternative Medicine 2022, pages 1-23.
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Pedro Mendes‐Bastos, Ana Brasileiro, Pavel Kolkhir, Stefan Frischbutter, Jörg Scheffel, Sherezade Moñino‐Romero & Marcus Maurer. (2022) Bruton's tyrosine kinase inhibition—An emerging therapeutic strategy in immune‐mediated dermatological conditions. Allergy 77:8, pages 2355-2366.
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Nicoletta CASSANO, Giovanni GENOVESE, Riccardo ASERO, Nunzio CRIMI, Antonio CRISTAUDO, Paolo DAPAVO, Ornella DE PITÀ, Silvia FERRUCCI, Maria T. FIERRO, Caterina FOTI, Giampiero GIROLOMONI, Eustachio NETTIS, Annamaria OFFIDANI, Annalisa PATRIZI, Patrizia PEPE, Paolo PIGATTO, Luca STINGENI, Angelo V. MARZANO & Gino A. VENA. (2022) Therapeutic management of chronic spontaneous urticaria in clinical practice: results from a pilot survey. Italian Journal of Dermatology and Venereology 157:1.
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Qianhua Zheng, Hui Zheng, Siyuan Zhou, Yunzhou Shi, Leixiao Zhang, Xianjun Xiao, Wei Zhang, Li Zhou, Ying Huang, Mingling Chen, Feng Zhong, Chuan Wang & Ying Li. (2022) Efficacy of acupuncture treatment for chronic spontaneous urticaria: study protocol for a randomised controlled trial. BMJ Open 12:2, pages e045027.
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Alexandra Maria Mortimore, Ramez Barsoum, Duncan Lambie & Erin McMeniman. (2021) A case of omalizumab as a successful treatment for telangiectasia macularis eruptiva perstans. Australasian Journal of Dermatology 63:1, pages 102-104.
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Lina Belmesk, Anastasiya Muntyanu, Emmanuelle Cantin, Zeinah AlHalees, Carolyn S. Jack, Michelle Le, Denis Sasseville, Lisa Iannattone, Moshe Ben-Shoshan, Ivan V. Litvinov & Elena Netchiporouk. (2021) Prominent Role of Type 2 Immunity in Skin Diseases: Beyond Atopic Dermatitis. Journal of Cutaneous Medicine and Surgery 26:1, pages 33-49.
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Maria Passante, Maddalena Napolitano, Stefano Dastoli, Luigi Bennardo, Gabriella Fabbrocini, Steven Paul Nisticò & Cataldo Patruno. (2021) Safety of omalizumab treatment in patients with chronic spontaneous urticaria and COVID‐19 . Dermatologic Therapy 34:6.
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Young-Min Ye. 2021. Urticaria - Diagnosis and Management. Urticaria - Diagnosis and Management.
Guido H. Falduto, Annika Pfeiffer, Andrea Luker, Dean D. Metcalfe & Ana Olivera. (2021) Emerging mechanisms contributing to mast cell-mediated pathophysiology with therapeutic implications. Pharmacology & Therapeutics 220, pages 107718.
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Erhan Ayhan, Murat Öztürk, İsa An & Muhammed Bekçİbaşi. (2020) COVID‐19 infection under omalizumab therapy for chronic spontaneous urticaria: three cases. International Journal of Dermatology 60:2, pages 253-254.
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Feras M. Ghazawi, Megan Lim, Jan P. Dutz & Mark G. Kirchhof. (2020) Infection risk of dermatologic therapeutics during the COVID‐19 pandemic: an evidence‐based recalibration. International Journal of Dermatology 59:9, pages 1043-1056.
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Ayman Abdelmaksoud, Mohamad Goldust & Michelangelo Vestita. (2020) Omalizumab and COVID‐19 treatment: Could it help? . Dermatologic Therapy 33:4.
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Stefano Passanisi, Stefania Arasi, Lucia Caminiti, Giuseppe Crisafulli, Giuseppina Salzano & Giovanni B. Pajno. (2020) Omalizumab in children and adolescents with chronic spontaneous urticaria: Case series and review of the literature. Dermatologic Therapy 33:4.
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William Lumry, Teri Templeton, Laurel Omert & Donald Levy. (2020) Advances in Hereditary Angioedema: The Prevention of Angioedema Attacks With Subcutaneous C1-Inhibitor Replacement Therapy. Journal of Infusion Nursing 43:3, pages 134-145.
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M. Alcántara Villar, J.C. Armario Hita, S. Cimbollek, M.D. Fernández Ballesteros, M. Galán Gutiérrez, C. Hernández Montoya, M.Á. Lara-Jiménez, J.J. Pereyra Rodríguez, J.M. Vega Chicote & R. Ruiz-Villaverde. (2020) A Review of the Latest Recommendations on the Management of Chronic Urticaria: A Multidisciplinary Consensus Statement From Andalusia, Spain. Actas Dermo-Sifiliográficas (English Edition) 111:3, pages 222-228.
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M. Alcántara Villar, J.C. Armario Hita, S. Cimbollek, M.D. Fernández Ballesteros, M. Galán Gutiérrez, C. Hernández Montoya, M.Á. Lara-Jiménez, J.J. Pereyra Rodríguez, J.M. Vega Chicote & R. Ruiz-Villaverde. (2020) Revisión de las últimas novedades en el manejo del paciente con urticaria crónica: Consenso multidisciplinar de la comunidad autónoma de Andalucía. Actas Dermo-Sifiliográficas 111:3, pages 222-228.
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Mehran Alizadeh Aghdam, Edward F. Knol, Mignon den Elzen, Constance Hartog Jager, Harmieke Os‐Medendorp, André C. Knulst, Henny G. Otten & Heike Röckmann. (2020) Response of FcεRI‐bearing leucocytes to omalizumab in chronic spontaneous urticaria. Clinical & Experimental Allergy 50:3, pages 364-371.
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Murat Türk, Leonor Carneiro-Leão, Pavel Kolkhir, Hanna Bonnekoh, Thomas Buttgereit & Marcus Maurer. (2020) How to Treat Patients with Chronic Spontaneous Urticaria with Omalizumab: Questions and Answers. The Journal of Allergy and Clinical Immunology: In Practice 8:1, pages 113-124.
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Yunzhou Shi, Hui Zheng, Siyuan Zhou, Qianhua Zheng, Leixiao Zhang, Xianjun Xiao, Wei Cao, Ying Liu & Ying Li. (2019) Efficacy and safety of acupuncture for patients with chronic urticaria: study protocol of a randomized, sham-controlled pilot trial. Trials 20:1.
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Andac Salman & Elif Comert. (2019) The Real-Life Effectiveness and Safety of Omalizumab Updosing in Patients With Chronic Spontaneous Urticaria. Journal of Cutaneous Medicine and Surgery 23:5, pages 496-500.
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Jesper G. Holm & Simon F. Thomsen. (2019) Omalizumab for atopic dermatitis: evidence for and against its use. Giornale Italiano di Dermatologia e Venereologia 154:4.
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Yunzhou Shi, Tinghui Hou, Qianhua Zheng, Ying Liu, Ting Yang & Ying Li. (2019) Acupoint catgut embedding for patients with chronic urticaria. Medicine 98:24, pages e16036.
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Yunzhou Shi, Siyuan Zhou, Qianhua Zheng, Ying Huang, Pingsheng Hao, Mingmin Xu, Leixiao Zhang, Xianjun Xiao, Hui Zheng & Ying Li. (2019) Systematic reviews of pharmacological and nonpharmacological treatments for patients with chronic urticaria. Medicine 98:20, pages e15711.
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Murat Türk, Marcus Maurer & İnsu Yılmaz. (2018) How to discontinue omalizumab in chronic spontaneous urticaria?. Allergy 74:4, pages 821-824.
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A. Hamelin, E. Amsler, P. Mathelier-Fusade, C. Pecquet, O. Bayrou, A. Barbaud & A. Soria. (2019) Traitement de l’urticaire chronique par omalizumab : données en vie réelle. Annales de Dermatologie et de Vénéréologie 146:1, pages 9-18.
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Mitsuru Adachi, Masanari Kozawa, Hajime Yoshisue, Ki Lee Milligan, Makoto Nagasaki, Takayoshi Sasajima, Terumasa Miyamoto & Ken Ohta. (2018) Real-world safety and efficacy of omalizumab in patients with severe allergic asthma: A long-term post-marketing study in Japan. Respiratory Medicine 141, pages 56-63.
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Miles Weinberger. (2018) Treatment with omalizumab or cyclosporine for resistant chronic spontaneous urticaria?. Annals of Allergy, Asthma & Immunology 120:3, pages 341-342.
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I. Cherrez Ojeda, E. Vanegas, M. Felix, V. Mata, S. Cherrez, D. Simancas-Racines, L. Greiding, J. Cano, A. Cherrez & Juan Carlos Calderon. (2018) Etiology of chronic urticaria: the Ecuadorian experience. World Allergy Organization Journal 11, pages 1.
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Rag?p Erta?. 2017. A Comprehensive Review of Urticaria and Angioedema. A Comprehensive Review of Urticaria and Angioedema.

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