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Expert Opinion on Biological Therapy Volume 18, 2018 - Issue 4
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Drug Evaluation

Atezolizumab for the treatment of colorectal cancer: the latest evidence and clinical potential

Gonzalo Tapia RicoDepartment of Medical Oncology, The Queen Elizabeth Hospital, Adelaide, South Australia, AustraliaView further author information
&
Timothy J. PriceDepartment of Medical Oncology, The Queen Elizabeth Hospital, Adelaide, South Australia, Australia;University of Adelaide, Adelaide, South Australia, AustraliaCorrespondence[email protected]
View further author information
Pages 449-457 | Received 07 Nov 2017, Accepted 19 Feb 2018, Published online: 23 Feb 2018

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Mengzhen Jiang, Man Liu, Guodi Liu, Jiawen Ma, Lixin Zhang & Shenlin Wang. (2023) Advances in the structural characterization of complexes of therapeutic antibodies with PD-1 or PD-L1. mAbs 15:1.
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Yan Li, Ming Qi, Feng Ding, Yong Lv, Jingyu Ma & Yufeng Zhu. (2021) Tumour targetable and microenvironment-responsive nanoparticles simultaneously disrupt the PD-1/PD-L1 pathway and MAPK/ERK/JNK pathway for efficient treatment of colorectal cancer. Journal of Drug Targeting 29:4, pages 454-465.
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Alexandre A. Jácome & Cathy Eng. (2019) Role of immune checkpoint inhibitors in the treatment of colorectal cancer: focus on nivolumab. Expert Opinion on Biological Therapy 19:12, pages 1247-1263.
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Articles from other publishers (20)

Vlad Alexandru Ionescu, Gina Gheorghe, Nicolae Bacalbasa, Alexandru Laurentiu Chiotoroiu & Camelia Diaconu. (2023) Colorectal Cancer: From Risk Factors to Oncogenesis. Medicina 59:9, pages 1646.
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Kaewta Rattanapisit, Christine Joy I. Bulaon, Richard Strasser, Hongyan Sun & Waranyoo Phoolcharoen. (2023) In vitro and in vivo studies of plant-produced Atezolizumab as a potential immunotherapeutic antibody. Scientific Reports 13:1.
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Samira Anbari, Hanwen Wang, Yu Zhang, Jun Wang, Minu Pilvankar, Masoud Nickaeen, Steven Hansel & Aleksander S. Popel. (2023) Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager. Frontiers in Pharmacology 14.
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Cody J. Peer, Keith T. Schmidt, Oluwatobi Arisa, William J. Richardson, Koosha Paydary, Daniel A. Goldstein, James L. Gulley, William D. Figg & Mark J. Ratain. (2023) In Silico Re‐Optimization of Atezolizumab Dosing Using Population Pharmacokinetic Simulation and Exposure–Response Simulation. The Journal of Clinical Pharmacology 63:6, pages 672-680.
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Dae Young Lee, Eunji Im, Dahye Yoon, Young-Seob Lee, Geum-Soog Kim, Donghwi Kim & Sung-Hoon Kim. (2022) Pivotal role of PD-1/PD-L1 immune checkpoints in immune escape and cancer progression: Their interplay with platelets and FOXP3+Tregs related molecules, clinical implications and combinational potential with phytochemicals. Seminars in Cancer Biology 86, pages 1033-1057.
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Linhan Zhang, Sheng Zhao, Huijie Jiang, Rongjun Zhang, Mingyu Zhang, Wenbin Pan, Zhongqi Sun, Dandan Wang & Jinping Li. (2022) Radioimmunotherapy study of 131I-labeled Atezolizumab in preclinical models of colorectal cancer. EJNMMI Research 12:1.
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Pietro Andrei, Paolo Battuello, Gaia Grasso, Emanuele Rovera, Nicolò Tesio & Alberto Bardelli. (2022) Integrated approaches for precision oncology in colorectal cancer: The more you know, the better. Seminars in Cancer Biology 84, pages 199-213.
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Yundi Zhang, Ke Zhang, Haoming Gong, Qin Li, Lajie Man, Qingchang Jin, Lin Zhang & Song Li. (2022) Links Between N6-Methyladenosine and Tumor Microenvironments in Colorectal Cancer. Frontiers in Cell and Developmental Biology 10.
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Ding-Kang Wang, Qian Zuo, Qing-Yu He & Bin Li. (2021) Targeted Immunotherapies in Gastrointestinal Cancer: From Molecular Mechanisms to Implications. Frontiers in Immunology 12.
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Elsa N. Garza Treviño, Paulina Delgado-Gonzalez, Carlos I. Valencia Salgado & Jorge L. Ortega Garcia. (2020) Pericytes Relationship with Cancer Stem Cells in the Colon. Current Tissue Microenvironment Reports 1:4, pages 187-198.
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Emmanouil Damilakis, Dimitrios Mavroudis, Maria Sfakianaki & John Souglakos. (2020) Immunotherapy in Metastatic Colorectal Cancer: Could the Latest Developments Hold the Key to Improving Patient Survival?. Cancers 12:4, pages 889.
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Qinlian Jiao, Yidan Ren, Abakundana Nsenga Ariston Gabrie, Qin Wang, Yuli Wang, Lutao Du, Xiaoyan Liu, Chuanxin Wang & Yun-shan Wang. (2020) Advances of immune checkpoints in colorectal cancer treatment. Biomedicine & Pharmacotherapy 123, pages 109745.
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Young-IL Jeong, So Young Yoo, Jeong Heo & Dae Hwan Kang. (2019) Chlorin e6-Conjugated and PEGylated Immune Checkpoint Inhibitor Nanocomposites for Pulmonary Metastatic Colorectal Cancer. ACS Omega 4:20, pages 18593-18599.
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Theodoulakis Christofi, Stavroula Baritaki, Luca Falzone, Massimo Libra & Apostolos Zaravinos. (2019) Current Perspectives in Cancer Immunotherapy. Cancers 11:10, pages 1472.
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Yeon Ji Chae, Jinil Kim, Hwon Heo, Chul-Woong Woo, Sang-Tae Kim, Min Jung Kim, Jong Rip Choi, Dae Hee Kim, Dong-Cheol Woo, Kyung Won Kim & Yoonseok Choi. (2019) Magnetic Resonance Colonography Enables the Efficacy Assessment of Immune Checkpoint Inhibitors in an Orthotopic Colorectal Cancer Mouse Model. Translational Oncology 12:9, pages 1264-1270.
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Mingyu Zhang, Huijie Jiang, Rongjun Zhang, Hao Jiang, Hailong Xu, Wenbin Pan, Xiaolin Gao & Zhongqi Sun. (2019) Near‐infrared fluorescence‐labeled anti‐PD‐L1‐mAb for tumor imaging in human colorectal cancer xenografted mice. Journal of Cellular Biochemistry 120:6, pages 10239-10247.
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Evangelos Koustas, Panagiotis Sarantis, Georgia Kyriakopoulou, Athanasios G. Papavassiliou & Michalis V. Karamouzis. (2019) The Interplay of Autophagy and Tumor Microenvironment in Colorectal Cancer—Ways of Enhancing Immunotherapy Action. Cancers 11:4, pages 533.
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Rebecca A. DeStefanis, Jeremy D. Kratz, Philip B. Emmerich & Dustin A. Deming. (2019) Targeted Therapy in Metastatic Colorectal Cancer: Current Standards and Novel Agents in Review. Current Colorectal Cancer Reports 15:2, pages 61-69.
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David Buka, Josef Dvořák, Igor Richter, Pavel Škrobánek, Tomáš Buchler & Bohuslav Melichar. (2019) Interactions Between Anti-Vegf Therapy and Antitumor Immunity as a Potential Therapeutic Strategy in Colorectal Cancer. Acta Medica (Hradec Kralove, Czech Republic) 62:3, pages 127-130.
Crossref
Paulo Matos & Peter Jordan. 2018. Targeted Therapy of Colorectal Cancer Subtypes. Targeted Therapy of Colorectal Cancer Subtypes 7 21 .

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