933
Views
22
CrossRef citations to date
0
Altmetric
Review

Anti-IL-4/IL-13 for the treatment of asthma: the story so far

ORCID Icon &
Pages 283-294 | Received 14 Oct 2019, Accepted 07 Jan 2020, Published online: 20 Jan 2020

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Wen-Chung Huang, Shu-Ju Wu, Li-Wen Fang, Tzu-Yung Lin & Chian-Jiun Liou. (2023) Phillyrin attenuates airway inflammation and Th2 cell activities in a mouse asthma model. Food and Agricultural Immunology 34:1.
Read now

Articles from other publishers (21)

Igor P. Shilovskiy, Valeriya I. Kovchina, Ekaterina D. Timotievich, Alexander A. Nikolskii & Musa R. Khaitov. (2023) Role and Molecular Mechanisms of Alternative Splicing of Th2-Cytokines IL-4 and IL-5 in Atopic Bronchial Asthma. Biochemistry (Moscow) 88:10, pages 1608-1621.
Crossref
L. E. Blazhevich, O. E. Smirnova, V. M. Kirilina & P. M. Masliukov. (2023) Research of the Expression of IL-13 Receptors and IL-13R Genes in the Bronch of Rats with Ovalbumin-Induced Bronchial Asthma. Journal of Evolutionary Biochemistry and Physiology 59:2, pages 630-641.
Crossref
Daniela Mokra, Romana Barosova & Juraj Mokry. (2023) Sex-Based Differences in Bronchial Asthma: What Are the Mechanisms behind Them?. Applied Sciences 13:4, pages 2694.
Crossref
Luigino Calzetta, Marina Aiello, Annalisa Frizzelli, Elena Pistocchini, Beatrice Ludovica Ritondo, Paola Rogliani & Alfredo Chetta. (2022) Investigational Treatments in Phase I and II Clinical Trials: A Systematic Review in Asthma. Biomedicines 10:9, pages 2330.
Crossref
Axel Nordström, Mattias Jangard, Marie Svedberg, Michael Ryott & Maria Kumlin. (2022) Levels of eicosanoids in nasal secretions associated with nasal polyp severity in chronic rhinosinusitis. Prostaglandins, Leukotrienes and Essential Fatty Acids 184, pages 102474.
Crossref
Wen-Chung Huang, Shu-Ju Wu, Kuo-Wei Yeh & Chian-Jiun Liou. (2022) Gypenoside A from Gynostemma pentaphyllum Attenuates Airway Inflammation and Th2 Cell Activities in a Murine Asthma Model. International Journal of Molecular Sciences 23:14, pages 7699.
Crossref
Corrado Pelaia, Giulia Pelaia, Claudia Crimi, Angelantonio Maglio, Giuseppe Armentaro, Cecilia Calabrese, Angela Sciacqua, Luca Gallelli & Alessandro Vatrella. (2022) Biological Therapy of Severe Asthma with Dupilumab, a Dual Receptor Antagonist of Interleukins 4 and 13. Vaccines 10:6, pages 974.
Crossref
Meng-Chun Wang, Wen-Chung Huang, Li-Chen Chen, Kuo-Wei Yeh, Chwan-Fwu Lin & Chian-Jiun Liou. (2022) Sophoraflavanone G from Sophora flavescens Ameliorates Allergic Airway Inflammation by Suppressing Th2 Response and Oxidative Stress in a Murine Asthma Model. International Journal of Molecular Sciences 23:11, pages 6104.
Crossref
Xinxiu Li, Eun Jung Lee, Sandra Lilja, Joseph Loscalzo, Samuel Schäfer, Martin Smelik, Maria Regina Strobl, Oleg Sysoev, Hui Wang, Huan Zhang, Yelin Zhao, Danuta R. Gawel, Barbara Bohle & Mikael Benson. (2022) A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets. Genome Medicine 14:1.
Crossref
Corrado Pelaia, Enrico Heffler, Claudia Crimi, Angelantonio Maglio, Alessandro Vatrella, Girolamo Pelaia & Giorgio Walter Canonica. (2022) Interleukins 4 and 13 in Asthma: Key Pathophysiologic Cytokines and Druggable Molecular Targets. Frontiers in Pharmacology 13.
Crossref
Koichi Ando, Yosuke Fukuda, Akihiko Tanaka & Hironori Sagara. (2022) Comparative Efficacy and Safety of Tezepelumab and Other Biologics in Patients with Inadequately Controlled Asthma According to Thresholds of Type 2 Inflammatory Biomarkers: A Systematic Review and Network Meta-Analysis. Cells 11:5, pages 819.
Crossref
Huan Lan, Zhongyu Gui, Zhen Zeng, Dayu Li, Bo Qian, Lin‐yuan Qin, Ling Dai & Jia‐Le Song. (2022) Oral administration of Lactobacillus plantarum CQPC11 attenuated the airway inflammation in an ovalbumin (OVA)‐induced Balb/c mouse model of asthma . Journal of Food Biochemistry 46:2.
Crossref
Shilovskiy IP, Sundukova MS, Korneev AV, Nikolskii AA, Barvinskaya ED, Kovchina VI, Vishniakova LI, Turenko VN, Yumashev KV, Kaganova MM, Brylina VE, Sergeev I, Maerle A, Kudlay DA, Petukhova O & Khaitov M.R. (2022) The mixture of siRNAs targeted to IL-4 and IL-13 genes effectively reduces the airway hyperreactivity and allergic inflammation in a mouse model of asthma. International Immunopharmacology 103, pages 108432.
Crossref
Andrew M. Abreo, Kevin S. Gipson & Luke A. Wall. 2022. Encyclopedia of Infection and Immunity. Encyclopedia of Infection and Immunity 586 595 .
Fabio L.M. Ricciardolo, Vitina Carriero & Francesca Bertolini. 2022. Encyclopedia of Respiratory Medicine. Encyclopedia of Respiratory Medicine 342 351 .
Fabio Luigi Massimo Ricciardolo, Francesca Bertolini & Vitina Carriero. (2021) The Role of Dupilumab in Severe Asthma. Biomedicines 9:9, pages 1096.
Crossref
Luigino Calzetta, Marina Aiello, Annalisa Frizzelli, Giuseppina Bertorelli, Paola Rogliani & Alfredo Chetta. (2021) Oral Corticosteroids Dependence and Biologic Drugs in Severe Asthma: Myths or Facts? A Systematic Review of Real-World Evidence. International Journal of Molecular Sciences 22:13, pages 7132.
Crossref
Shu-Ju Wu, Chian-Jiun Liou, Ya-Ling Chen, Shu-Chen Cheng & Wen-Chung Huang. (2021) Fucoxanthin Ameliorates Oxidative Stress and Airway Inflammation in Tracheal Epithelial Cells and Asthmatic Mice. Cells 10:6, pages 1311.
Crossref
Jingwei Shi, Xujun Song, Benno Traub, Michael Luxenhofer & Marko Kornmann. (2021) Involvement of IL-4, IL-13 and Their Receptors in Pancreatic Cancer. International Journal of Molecular Sciences 22:6, pages 2998.
Crossref
Cornelis J M Melief. (2021) Special Review: The future of Immunotherapy. Immunotherapy Advances 1:1.
Crossref
Archita Ray, Sabita Singh, Joytri Dutta & Ulaganathan Mabalirajan. 2021. Targeting Cellular Signalling Pathways in Lung Diseases. Targeting Cellular Signalling Pathways in Lung Diseases 27 51 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.