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Expert Opinion on Biological Therapy Volume 20, 2020 - Issue 3
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Drug Evaluation

Pembrolizumab for the treatment of colorectal cancer

Dahna CoupezDigestive Oncology, Institut Des Maladies De l’Appareil Digestif, Centre Hospitalier Universitaire De Nantes, Nantes, FranceView further author information
,
Pauline HuloDigestive Oncology, Institut Des Maladies De l’Appareil Digestif, Centre Hospitalier Universitaire De Nantes, Nantes, France;Centre De Recherche En Cancérologie Et Immunologie Nantes-Angers (CRCINA), INSERM, Université d’Angers, Université De Nantes, Nantes, FranceView further author information
,
Yann TouchefeuDigestive Oncology, Institut Des Maladies De l’Appareil Digestif, Centre Hospitalier Universitaire De Nantes, Nantes, FranceView further author information
,
Céline BossardService d’Anatomie Et Cytologie Pathologiques, Centre Hospitalier Universitaire, Nantes, FranceView further author information
&
Jaafar BennounaDigestive Oncology, Institut Des Maladies De l’Appareil Digestif, Centre Hospitalier Universitaire De Nantes, Nantes, France;Centre De Recherche En Cancérologie Et Immunologie Nantes-Angers (CRCINA), INSERM, Université d’Angers, Université De Nantes, Nantes, FranceCorrespondence[email protected]
View further author information
Pages 219-226 | Received 01 Sep 2019, Accepted 15 Jan 2020, Published online: 03 Feb 2020

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Louis Plüss, Frederik Peissert, Abdullah Elsayed, Giulia Rotta, Jonas Römer, Sheila Dakhel Plaza, Alessandra Villa, Emanuele Puca, Roberto De Luca, Annette Oxenius & Dario Neri. (2023) Generation and in vivo characterization of a novel high-affinity human antibody targeting carcinoembryonic antigen. mAbs 15:1.
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Paolo Tarantino, Romualdo Barroso-Sousa, Ana C. Garrido-Castro, Sandra S. McAllister, Jennifer L. Guerriero, Elizabeth Mittendorf, Giuseppe Curigliano & Sara M. Tolaney. (2022) Understanding resistance to immune checkpoint inhibitors in advanced breast cancer. Expert Review of Anticancer Therapy 22:2, pages 141-153.
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Jian Yang, Feng Bi & Hongfeng Gou. (2021) Complete Pathologic Response After Concurrent Treatment with Pembrolizumab and Radiotherapy in Metastatic Colorectal Cancer: A Case Report. OncoTargets and Therapy 14, pages 2555-2561.
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Xianzhe Yu, Lingling Zhu, Jiewei Liu, Ming Xie, Jiang Chen & Jianguo Li. (2020) Emerging Role of Immunotherapy for Colorectal Cancer with Liver Metastasis. OncoTargets and Therapy 13, pages 11645-11658.
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Articles from other publishers (12)

Chao Li, Ulrich Wirth, Josefine Schardey, Viktor V. Ehrlich-Treuenstätt, Alexandr V. Bazhin, Jens Werner & Florian Kühn. (2023) An immune-related gene prognostic index for predicting prognosis in patients with colorectal cancer. Frontiers in Immunology 14.
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Mayur M. Amonkar, Lauren A. Abderhalden, Andrew M. Frederickson, Audrone Aksomaityte, Brian M. Lang, Pierre Leconte & Ina Zhang. (2023) Clinical outcomes of chemotherapy-based therapies for previously treated advanced colorectal cancer: a systematic literature review and meta-analysis. International Journal of Colorectal Disease 38:1.
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Pramodkumar P. Gupta, Mala M. Parab, Santosh S. Chhajed & Virupaksha A. Bastikar. 2023. Protein-based Therapeutics. Protein-based Therapeutics 275 296 .
Frederik Peissert, Louis Plüss, Anna Maria Giudice, Tiziano Ongaro, Alessandra Villa, Abdullah Elsayed, Lisa Nadal, Sheila Dakhel Plaza, Luigi Scietti, Emanuele Puca, Roberto De Luca, Federico Forneris & Dario Neri. (2022) Selection of a PD ‐1 blocking antibody from a novel fully human phage display library . Protein Science 31:12.
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Lili Huang, Huaxin Zhao, Mengying Shan, Hong Chen, Bin Xu, Yang He, Yu Zhao, Zhuqing Liu, Jianhua Chen & Qing Xu. (2022) Oncolytic adenovirus H101 ameliorate the efficacy of anti‐PD ‐1 monotherapy in colorectal cancer . Cancer Medicine 11:23, pages 4575-4587.
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Jiawei Chen, Haodong Zhu, Yuhang Yin, Siyuan Jia & Xiangjian Luo. (2022) Colorectal cancer: Metabolic interactions reshape the tumor microenvironment. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1877:5, pages 188797.
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Ming Yang, Olamide Tosin Olaoba, Chunye Zhang, Eric T. Kimchi, Kevin F. Staveley-O’Carroll & Guangfu Li. (2022) Cancer Immunotherapy and Delivery System: An Update. Pharmaceutics 14:8, pages 1630.
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Sara Cherri, Ester Oneda, Silvia Noventa, Laura Melocchi & Alberto Zaniboni. (2022) Microsatellite instability and chemosensitivity in solid tumours. Therapeutic Advances in Medical Oncology 14, pages 175883592210993.
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Monika Berbecka, Alicja Forma, Jacek Baj, Marzena Furtak-Niczyporuk, Ryszard Maciejewski & Robert Sitarz. (2021) A Systematic Review of the Cyclooxygenase-2 (COX-2) Expression in Rectal Cancer Patients Treated with Preoperative Radiotherapy or Radiochemotherapy. Journal of Clinical Medicine 10:19, pages 4443.
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N.A. Bhaskaran & L. Kumar. (2021) Treating colon cancers with a non-conventional yet strategic approach: An overview of various nanoparticulate systems. Journal of Controlled Release 336, pages 16-39.
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Junge Bai, Hongsheng Chen & Xuefeng Bai. (2021) Relationship between microsatellite status and immune microenvironment of colorectal cancer and its application to diagnosis and treatment. Journal of Clinical Laboratory Analysis 35:6.
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Huilin Ma, Hanwen Wang, Richard J Sové, Jun Wang, Craig Giragossian & Aleksander S Popel. (2020) Combination therapy with T cell engager and PD-L1 blockade enhances the antitumor potency of T cells as predicted by a QSP model. Journal for ImmunoTherapy of Cancer 8:2, pages e001141.
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