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Expert Opinion on Biological Therapy Volume 21, 2021 - Issue 9
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Original Research

Use of brodalumab for the treatment of chronic plaque psoriasis: a one-year real-life study in the Lazio region, Italy

M Galluzzoa Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome, Italy;b Dermatology Unit, Fondazione Policlinico Tor Vergata, Rome, ItalyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-3424-5175View further author information
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G Caldarolac Dipartimento Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Dermatologia, Rome, Italy;d Dermatologia, Università Cattolica Del Sacro Cuore, Dermatologia, Rome, ItalyORCID Iconhttps://orcid.org/0000-0002-8837-9232View further author information
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C De Simonec Dipartimento Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Dermatologia, Rome, Italy;d Dermatologia, Università Cattolica Del Sacro Cuore, Dermatologia, Rome, ItalyView further author information
,
N Bernardinie Dermatology Unit, Sapienza University of Rome, Latina, ItalyView further author information
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G Morettaf Dermatology Unit, Istituto Dermopatico dell’Immacolata IDI-IRCCS, Rome, ItalyORCID Iconhttps://orcid.org/0000-0002-8839-5961View further author information
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S Pallottaf Dermatology Unit, Istituto Dermopatico dell’Immacolata IDI-IRCCS, Rome, ItalyORCID Iconhttps://orcid.org/0000-0003-4827-2892View further author information
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E Bottib Dermatology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy;g Department of Systems Medicine, University of Rome “Tor Vergata”, Rome, ItalyView further author information
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E Campioneb Dermatology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy;g Department of Systems Medicine, University of Rome “Tor Vergata”, Rome, ItalyORCID Iconhttps://orcid.org/0000-0001-7447-6798View further author information
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F Pirroc Dipartimento Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Dermatologia, Rome, Italy;d Dermatologia, Università Cattolica Del Sacro Cuore, Dermatologia, Rome, ItalyORCID Iconhttps://orcid.org/0000-0001-6629-9613View further author information
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C. Potenzae Dermatology Unit, Sapienza University of Rome, Latina, ItalyView further author information
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L Bianchib Dermatology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy;g Department of Systems Medicine, University of Rome “Tor Vergata”, Rome, ItalyORCID Iconhttps://orcid.org/0000-0001-8697-6896View further author information
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K Perisc Dipartimento Scienze Mediche E Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Dermatologia, Rome, Italy;d Dermatologia, Università Cattolica Del Sacro Cuore, Dermatologia, Rome, ItalyORCID Iconhttps://orcid.org/0000-0002-5237-0463View further author information
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Pages 1299-1310 | Received 02 May 2021, Accepted 08 Jun 2021, Published online: 28 Jun 2021

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Sara Cacciapuoti, Luca Potestio, Gianluca Guerrasio, Gabriella Fabbrocini, Massimiliano Scalvenzi, Angelo Ruggiero, Giuseppina Caiazzo & Matteo Megna. (2023) Effectiveness of Brodalumab in Patients with Moderate-to-Severe Plaque Psoriasis Located in Difficult-to-Treat Areas. Clinical, Cosmetic and Investigational Dermatology 16, pages 2637-2644.
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Luca Mastorino, C. Cariti, S. Susca, S. Boskovic, C. Aquino, M. Ortoncelli, E. Stroppiana, A. Verrone, P. Dapavo, P. Quaglino & Simone Ribero. (2022) Brodalumab efficacy in bio-naïve psoriasis patients: real-life experience of 202 subjects up to 48 weeks. Journal of Dermatological Treatment 33:8, pages 3211-3213.
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Caterina Lanna, Sara Lambiase, Ruslana Gaeta Shumak, Cristiana Borselli, Terenzio Cosio, Annunziata Dattola, Luca Bianchi & Elena Campione. (2022) Why targeted therapeutics have provided benefit in psoriasis: looking at IL-17 biology. Expert Review of Clinical Pharmacology 15:10, pages 1209-1224.
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Evangelia Papadavid, Efterpi Zafeiriou, Sophia Georgiou, Angeliki-Viktoria Roussaki-Schulze, Theofanis Spiliopoulos, Eleftheria Vryzaki, Chrysa Oikonomou, Ourania Drongoula, Maria Boziou, Georgios Goudouras, Konstantinos Sfaelos, Zoi Apalla & Elisavet Lazaridou. (2022) Real-world clinical outcomes of treatment with brodalumab in patients with moderate-to-severe psoriasis: a retrospective, 24-month experience from four academic dermatology centers in Greece. Journal of Dermatological Treatment 33:7, pages 3053-3059.
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Francesco Messina & Stefano Piaserico. (2022) The dark side of the moon: the immune-mediated adverse events of IL-17A/IL-17R inhibition. Journal of Dermatological Treatment 33:5, pages 2443-2454.
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Philip Hampton, Emma Borg, Jes Birger Hansen & Matthias Augustin. (2021) Efficacy of Brodalumab and Guselkumab in Patients with Moderate-to-Severe Plaque Psoriasis Who are Inadequate Responders to Ustekinumab: A Matching Adjusted Indirect Comparison. Psoriasis: Targets and Therapy 11, pages 123-131.
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Natalia Rompoti, Maria Politou, Irene Stefanaki, Charitomeni Vavouli, Marina Papoutsaki, Afroditi Neofotistou, Dimitrios Rigopoulos, Alexander Stratigos & Electra Nicolaidou. (2023) Brodalumab in plaque psoriasis: Real‐world data on effectiveness, safety and clinical predictive factors of initial response and drug survival over a period of 104 weeks. Journal of the European Academy of Dermatology and Venereology 37:4, pages 689-697.
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Matteo Megna, Luca Potestio, Elisa Camela, Gabriella Fabbrocini & Angelo Ruggiero. (2022) Ixekizumab and brodalumab indirect comparison in the treatment of moderate to severe psoriasis: Results from an Italian single‐center retrospective study in a real‐life setting. Dermatologic Therapy 35:9.
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Michał Jarocki, Julia Karska, Szymon Kowalski, Paweł Kiełb, Łukasz Nowak, Wojciech Krajewski, Jolanta Saczko, Julita Kulbacka, Tomasz Szydełko & Bartosz Małkiewicz. (2022) Interleukin 17 and Its Involvement in Renal Cell Carcinoma. Journal of Clinical Medicine 11:17, pages 4973.
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Eleftheria Tampouratzi, Markos Papakonstantis, John Katsantonis, Theodoros Sidiropoulos, Florentina Delli, Konstantinos Efthymiadis, Konstantinos Sfaelos, Athina Christodoulou, Vasiliki Chasapi & Pantelis Panagakis. (2022) Clinical evidence on the use of brodalumab for the treatment of psoriasis in Greece: Experience from clinical practice of four tertiary hospitals. Dermatologic Therapy 35:7.
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Marloes E. Van Muijen, Sarah E. Thomas, Hans M.M. Groenewoud, Marisol E. Otero, Paul M. Ossenkoppele, Marcellus D. Njoo, Sharon R.P. Dodemont, Else N. Kop, Maartje A.M. Berends, Marjolein I.A. Koetsier, Johannes M. Mommers, John E.M. Körver, Ron A. Tupker, Marjolein S. De Bruin-Weller, Lizelotte J.M.T. Weppner-Parren, Bas Peters, Marloes M. Kleinpenning, Astrid L.A. Kuijpers, W. Peter Arnold, Paula P.M. Van Lümig, Juul M.P.A. Van den Reek & Elke M.G.J. De Jong. (2022) Direct Comparison of Real-world Effectiveness of Biologics for Psoriasis using Absolute and Relative Psoriasis Area and Severity Index Scores in a Prospective Multicentre Cohort. Acta Dermato-Venereologica 102, pages adv00712.
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. (2022) Antipsoriatics. Reactions Weekly 1896:1, pages 56-56.
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Valerio Caputo, Claudia Strafella, Terenzio Cosio, Caterina Lanna, Elena Campione, Giuseppe Novelli, Emiliano Giardina & Raffaella Cascella. (2021) Pharmacogenomics: An Update on Biologics and Small-Molecule Drugs in the Treatment of Psoriasis. Genes 12:9, pages 1398.
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