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Factor XI inhibition fulfilling the optimal expectations for ideal anticoagulation

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Pages 55-61 | Received 18 Nov 2018, Accepted 04 Mar 2019, Published online: 18 Mar 2019

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Sandra Elsheikh, Nicola Tidbury & Gregory Y.H. Lip. (2023) A review of emerging factor XI inhibitors. Expert Opinion on Emerging Drugs 28:1, pages 43-53.
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Nan Zhao, Qian Xiang, Zhiyan Liu, Xia Zhao & Yimin Cui. (2020) Pharmacokinetic-Pharmacodynamic Analysis’ Role in Design of Phase ⅠClinical Trials of Anticoagulant Agents: A Systematic Review. Expert Review of Clinical Pharmacology 13:11, pages 1191-1202.
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Sylwia Modrzycka, Sonia Kołt, Ty E. AdamsStanisław Potoczek, James A. HuntingtonPaulina Kasperkiewicz & Marcin Drąg. (2023) Fluorescent Activity-Based Probe To Image and Inhibit Factor XIa Activity in Human Plasma. Journal of Medicinal Chemistry 66:6, pages 3785-3797.
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Yu Lei, Bing Zhang, Yan Zhang, Xiwen Dai, Yulin Duan, Qing Mao, Jun Gao, Yuwei Yang, Ziyang Bao, Xuefeng Fu, Kunqi Ping, Chengda Yan, Yanhua Mou & Shaojie Wang. (2021) Design, synthesis and biological evaluation of novel FXIa inhibitors with 2-phenyl-1H-imidazole-5-carboxamide moiety as P1 fragment. European Journal of Medicinal Chemistry 220, pages 113437.
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Diana A. Gorog & Gregory Y.H. Lip. (2019) Impaired Spontaneous/Endogenous Fibrinolytic Status as New Cardiovascular Risk Factor?. Journal of the American College of Cardiology 74:10, pages 1366-1375.
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