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Expert Opinion on Therapeutic Targets Volume 20, 2016 - Issue 11
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Review

Targeting glia for bone cancer pain

Ya-Qun ZhouResearch Center for Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
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Zheng LiuDepartment of Urology, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, Wuhan, ChinaView further author information
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Hui-Quan LiuCancer Center, Tongji Hospital, Tongji Medical college, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
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Dai-Qiang LiuResearch Center for Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
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Shu-Ping ChenResearch Center for Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
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Da-Wei YeCancer Center, Tongji Hospital, Tongji Medical college, Huazhong University of Science and Technology, Wuhan, ChinaCorrespondence[email protected]
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Yu-Ke TianResearch Center for Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China;Department of Anesthesiology and Pain Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaView further author information
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Pages 1365-1374 | Received 18 May 2016, Accepted 15 Jul 2016, Published online: 27 Jul 2016

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Jun Tian, Tieying Song, Hong Wang, Wenli Wang, Zaiwang Zhang & Ruyu Yan. (2019) Thalidomide alleviates bone cancer pain by down-regulating expressions of NF-κB and GFAP in spinal astrocytes in a mouse model. International Journal of Neuroscience 129:9, pages 896-903.
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Articles from other publishers (32)

Huan-Jun Lu, Xiao-Bo Wu & Qian-Qi Wei. (2023) Ion channels in cancer-induced bone pain: from molecular mechanisms to clinical applications. Frontiers in Molecular Neuroscience 16.
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Xihan Li, Yu Chen, Jialun Wang, Chengfei Jiang & Ying Huang. (2021) Lung Cancer Cell-Derived Exosomal let-7d-5p Down-Regulates OPRM1 to Promote Cancer-Induced Bone Pain. Frontiers in Cell and Developmental Biology 9.
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Han-Wen Chen, Xiao-Xia Zhang, Zhu-Ding Peng, Zu-Min Xing, Yi-Wen Zhang & Ya-Lan Li. (2021) The circular RNA circSlc7a11 promotes bone cancer pain pathogenesis in rats by modulating LLC-WRC 256 cell proliferation and apoptosis. Molecular and Cellular Biochemistry 476:4, pages 1751-1763.
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Zengli Zhang, Meiling Deng, Jiangju Huang, Jing Wu, Zhengyiqi Li, Manyu Xing, Jian Wang, Qulian Guo & Wangyuan Zou. (2020) Microglial annexin A3 downregulation alleviates bone cancer-induced pain through inhibiting the Hif-1α/vascular endothelial growth factor signaling pathway. Pain 161:12, pages 2750-2762.
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Meng-Meng Ge, Ya-Qun Zhou, Xue-Bi Tian, Anne Manyande, Yu-Ke Tian, Da-Wei Ye & Hui Yang. (2020) Src-family protein tyrosine kinases: A promising target for treating chronic pain. Biomedicine & Pharmacotherapy 125, pages 110017.
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Aitao Wang, Muer Tie, Dongmei Guo, Na Wu, Shanglong Yao, Limei Yan & Xingsheng Zhao. (2019) A Novel Mechanism of BAM8-22 Inhibiting Microglia Activation: Represses CX3CR1 Expression via Upregulating miR-184. Journal of Molecular Neuroscience 70:4, pages 550-558.
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Sophia H. Zhang, Galina V. Shurin, Hasan Khosravi, Rashek Kazi, Oleg Kruglov, Michael R. Shurin & Yuri L. Bunimovich. (2019) Immunomodulation by Schwann cells in disease. Cancer Immunology, Immunotherapy 69:2, pages 245-253.
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David M. Vail, Douglas H. Thamm & Julias M. Liptak. 2020. Withrow and MacEwen's Small Animal Clinical Oncology. Withrow and MacEwen's Small Animal Clinical Oncology 286 329 .
Jia Sun, Ya-Qun Zhou, Shu-Ping Chen, Xiao-mei Wang, Bing-Yang Xu, Dan-Yang Li, Yu-Ke Tian & Da-Wei Ye. (2019) The endocannabinoid system: Novel targets for treating cancer induced bone pain. Biomedicine & Pharmacotherapy 120, pages 109504.
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German V. Martyn, Galina V. Shurin, Anton A. Keskinov, Yuri L. Bunimovich & Michael R. Shurin. (2019) Schwann cells shape the neuro-immune environs and control cancer progression. Cancer Immunology, Immunotherapy 68:11, pages 1819-1829.
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Meng-Meng Ge, Shu-Ping Chen, Ya-Qun Zhou, Zheng Li, Xue-Bi Tian, Feng Gao, Anne Manyande, Yu-Ke Tian & Hui Yang. (2019) The therapeutic potential of GABA in neuron-glia interactions of cancer-induced bone pain. European Journal of Pharmacology 858, pages 172475.
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Fu‑Dong Yao, Jun‑Qi Yang, Yuan‑Chi Huang, Ming‑Peng Luo, Wen‑Jie Yang, Bo Zhang & Xia‑Jun Liu. (2019) Antinociceptive effects of Ginsenoside Rb1 in a rat model of cancer‑induced bone pain. Experimental and Therapeutic Medicine.
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Ya-Qun Zhou, Dai-Qiang Liu, Shu-Ping Chen, Jia Sun, Xue-Rong Zhou, Cui Xing, Da-Wei Ye & Yu-Ke Tian. (2019) The Role of CXCR3 in Neurological Diseases. Current Neuropharmacology 17:2, pages 142-150.
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Miao Xu, Huadong Ni, Longsheng Xu, Hui Shen, Housheng Deng, Yungong Wang & Ming Yao. (2019) B14 ameliorates bone cancer pain through downregulating spinal interleukin-1β via suppressing neuron JAK2/STAT3 pathway. Molecular Pain 15, pages 174480691988649.
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Huan Wang, Xiaohui Li, Xianqiao Xie, Haiwen Zhao, Yan Gao, Yang Li, Xueqin Xu, Xiaofei Zhang, Changbin Ke & Juying Liu. (2019) Promotion of bone cancer pain development by decorin is accompanied by modification of excitatory synaptic molecules in the spinal cord. Molecular Pain 15, pages 174480691986425.
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Joshua Havelin & Tamara King. (2018) Mechanisms Underlying Bone and Joint Pain. Current Osteoporosis Reports 16:6, pages 763-771.
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Pengtao Li, Quan Zhang, Zhi Xiao, Shouyang Yu, Yan Yan & Ying Qin. (2018) Activation of the P2X 7 receptor in midbrain periaqueductal gray participates in the analgesic effect of tramadol in bone cancer pain rats . Molecular Pain 14, pages 174480691880303.
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Shu-Ping Chen, Jia Sun, Ya-Qun Zhou, Fei Cao, Cody Braun, Fang Luo, Da-Wei Ye & Yu-Ke Tian. (2018) Sinomenine attenuates cancer-induced bone pain via suppressing microglial JAK2/STAT3 and neuronal CAMKII/CREB cascades in rat models. Molecular Pain 14, pages 174480691879323.
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