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Expert Opinion on Therapeutic Targets Volume 21, 2017 - Issue 6
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Review

Targetting PED/PEA-15 for diabetes treatment

Francesca FioryNational Council of Research, URT of the Institute of Experimental Endocrinology and Oncology “G. Salvatore”, Naples, Italy;Department of Translational Medical Sciences, University of Naples “Federico II”, Naples, ItalyView further author information
,
Rosa SpinelliNational Council of Research, URT of the Institute of Experimental Endocrinology and Oncology “G. Salvatore”, Naples, Italy;Department of Translational Medical Sciences, University of Naples “Federico II”, Naples, ItalyView further author information
,
Gregory Alexander RacitiNational Council of Research, URT of the Institute of Experimental Endocrinology and Oncology “G. Salvatore”, Naples, Italy;Department of Translational Medical Sciences, University of Naples “Federico II”, Naples, ItalyView further author information
,
Luca ParrilloNational Council of Research, URT of the Institute of Experimental Endocrinology and Oncology “G. Salvatore”, Naples, Italy;Department of Translational Medical Sciences, University of Naples “Federico II”, Naples, ItalyView further author information
,
Vittoria D’espositoNational Council of Research, URT of the Institute of Experimental Endocrinology and Oncology “G. Salvatore”, Naples, Italy;Department of Translational Medical Sciences, University of Naples “Federico II”, Naples, ItalyView further author information
,
Pietro FormisanoNational Council of Research, URT of the Institute of Experimental Endocrinology and Oncology “G. Salvatore”, Naples, Italy;Department of Translational Medical Sciences, University of Naples “Federico II”, Naples, ItalyView further author information
,
Claudia MieleNational Council of Research, URT of the Institute of Experimental Endocrinology and Oncology “G. Salvatore”, Naples, Italy;Department of Translational Medical Sciences, University of Naples “Federico II”, Naples, ItalyView further author information
&
Francesco BeguinotNational Council of Research, URT of the Institute of Experimental Endocrinology and Oncology “G. Salvatore”, Naples, Italy;Department of Translational Medical Sciences, University of Naples “Federico II”, Naples, ItalyCorrespondence[email protected]
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Pages 571-581 | Received 30 Nov 2016, Accepted 06 Apr 2017, Published online: 21 Apr 2017

Citations (6)

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Fan Yang, Shengxun Zhao, Xuyan Zhang, Sheng Ding & Yancheng Xu. (2022) RNF6 Targeted by miR-26a-5p Protects Pancreatic β-Cell Function Against Type 2 Diabetes. Diabetes, Metabolic Syndrome and Obesity 15, pages 93-102.
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Articles from other publishers (5)

Emily C. Graff, J. Nicholas Cochran, Christopher B. Kaelin, Kenneth Day, Heather L. Gray-Edwards, Rie Watanabe, Jey W. Koehler, Rebecca A. Falgoust, Jeremy W. Prokop, Richard M. Myers, Nancy R. Cox, Gregory S. Barsh & Douglas R. Martin. (2020) PEA15 loss of function and defective cerebral development in the domestic cat. PLOS Genetics 16:12, pages e1008671.
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R. Spinelli, L. Parrillo, M. Longo, P. Florese, A. Desiderio, F. Zatterale, C. Miele, G. Alexander Raciti & F. Beguinot. (2020) Molecular basis of ageing in chronic metabolic diseases. Journal of Endocrinological Investigation 43:10, pages 1373-1389.
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Sergio L. Crespo-Flores, Andres Cabezas, Sherouk Hassan & Yufeng Wei. (2019) PEA-15 C-Terminal Tail Allosterically Modulates Death-Effector Domain Conformation and Facilitates Protein–Protein Interactions. International Journal of Molecular Sciences 20:13, pages 3335.
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Mohammad Hassan Baig, Mohd Adnan Kausar, Fohad Mabood Husain, Shazi Shakil, Irfan Ahmad, Brijesh S. Yadav & Mohd Saeed. (2019) Interfering PLD1-PED/PEA15 interaction using self-inhibitory peptides: An in silico study to discover novel therapeutic candidates against type 2 diabetes. Saudi Journal of Biological Sciences 26:1, pages 160-164.
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Viviana Vastolo, Immacolata Cristina Nettore, Marco Ciccarelli, Luigi Albano, Gregory Alexander Raciti, Michele Longo, Francesco Beguinot & Paola Ungaro. (2018) High-fat diet unveils an enhancer element at the Ped/Pea-15 gene responsible for epigenetic memory in skeletal muscle. Metabolism 87, pages 70-79.
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