565
Views
29
CrossRef citations to date
0
Altmetric
Review

Targeting A3 and A2A adenosine receptors in the fight against cancer

, , , , , & show all
Pages 669-678 | Received 28 Mar 2019, Accepted 07 Jun 2019, Published online: 12 Jun 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Yasser Tabana, Tae Chul Moon, Arno Siraki, Shokrollah Elahi & Khaled Barakat. (2021) Reversing T-cell exhaustion in immunotherapy: a review on current approaches and limitations. Expert Opinion on Therapeutic Targets 25:5, pages 347-363.
Read now

Articles from other publishers (28)

Rui-Jia Zhang, Qian-Ru Rao, Xue-Qin Jiang, Neng Ye, Na Li, Hong-Ling Du, Shun-Jie Zhang, Hao-Yu Ye, Wen-Shuang Wu & Min Zhao. (2023) Exploring the Immunomodulatory Properties of Red Onion ( Allium cepa L.) Skin: Isolation, Structural Elucidation, and Bioactivity Study of Novel Onion Chalcones Targeting the A 2A Adenosine Receptor . Journal of Agricultural and Food Chemistry.
Crossref
Jonas Goßen, Rui Pedro Ribeiro, Dirk Bier, Bernd Neumaier, Paolo Carloni, Alejandro Giorgetti & Giulia Rossetti. (2023) AI-based identification of therapeutic agents targeting GPCRs: introducing ligand type classifiers and systems biology. Chemical Science 14:32, pages 8651-8661.
Crossref
Santha Kumari Merugu, V. B. R. Krishnan K, Ravi Kumar K, Siddique Akber Ansari, Irfan Aamer Ansari & Hari Babu Bollikolla. (2023) Synthesis, Anticancer Evaluation and in Silico Studies of 1,4‐Dihydropyridines . Chemistry & Biodiversity.
Crossref
Liujun Zeng, Can Wang, Zijia Wang, Haofeng Xiong, Tianyi Zhang, Weijun Chen, Xin Hu & Tong Su. (2023) A2b and A3 adenosine receptors may act as promotive and prognostic factors in oral squamous cell carcinoma. Journal of Cranio-Maxillofacial Surgery 51:7-8, pages 508-515.
Crossref
Yangyang Tian, Jiarui Xia, Guo Yang, Chao Li, Yuanmeng Qi, Kai Dai, Chenchen Wu, Yonghua Guo, Wu Yao & Changfu Hao. (2023) A2aR inhibits fibrosis and the EMT process in silicosis by regulating Wnt/β-catenin pathway. Ecotoxicology and Environmental Safety 249, pages 114410.
Crossref
Kenneth A. Jacobson, Paola Oliva & R. Rama Suresh. 2023.
Daniela Catarzi, Flavia Varano, Sara Calenda, Erica Vigiani & Vittoria Colotta. 2023.
N. B. Serebryanaya, E. E. Fomicheva & P. P. Yakutseni. (2022) Purinergic Regulation of Neuroinflammation in Traumatic Brain Injury. Neuroscience and Behavioral Physiology 52:7, pages 1093-1106.
Crossref
Vishnu S. Mishra, Sachin Patil, Puli Chandramouli Reddy & Bimlesh Lochab. (2022) Combinatorial delivery of CPI444 and vatalanib loaded on PEGylated graphene oxide as an effective nanoformulation to target glioblastoma multiforme: In vitro evaluation. Frontiers in Oncology 12.
Crossref
Shuhao Liu, Wen Ding, Weifeng Huang, Zhijing Zhang, Yinfeng Guo, Qiyi Zhang, Linna Wu, Yukai Li, Rui Qin, Jiahao Li, Taoda Shi, Xiaolei Zhang, Jinping Lei & Wenhao Hu. (2022) Discovery of Novel Benzo[4,5]imidazo[1,2- a ]pyrazin-1-amine-3-amide-one Derivatives as Anticancer Human A 2A Adenosine Receptor Antagonists . Journal of Medicinal Chemistry 65:13, pages 8933-8947.
Crossref
Kenneth A. Jacobson, Zhan‐Guo Gao, Pierre Matricon, Matthew T. Eddy & Jens Carlsson. (2020) Adenosine A 2A receptor antagonists: from caffeine to selective non‐xanthines . British Journal of Pharmacology 179:14, pages 3496-3511.
Crossref
Lucía Celada, Tamara Cubiella, Jaime San-Juan-Guardado, Andrés San José Martínez, Nuria Valdés, Paula Jiménez-Fonseca, Ignacio Díaz, Jose María Enguita, Aurora Astudillo, Enol Álvarez-González, Luisa María Sierra & María-Dolores Chiara. (2022) Differential HIF2α Protein Expression in Human Carotid Body and Adrenal Medulla under Physiologic and Tumorigenic Conditions. Cancers 14:12, pages 2986.
Crossref
Hao-Yun Luo, Hai-Ying Shen, R. Serene Perkins & Ya-Xu Wang. (2022) Adenosine Kinase on Deoxyribonucleic Acid Methylation: Adenosine Receptor-Independent Pathway in Cancer Therapy. Frontiers in Pharmacology 13.
Crossref
André E. Nel, Kuo-Ching Mei, Yu-Pei Liao & Xiangsheng Liu. (2022) Multifunctional Lipid Bilayer Nanocarriers for Cancer Immunotherapy in Heterogeneous Tumor Microenvironments, Combining Immunogenic Cell Death Stimuli with Immune Modulatory Drugs. ACS Nano 16:4, pages 5184-5232.
Crossref
Elisabetta Coppi, Federica Cherchi, Martina Venturini, Elena Lucarini, Renato Corradetti, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Felicita Pedata & Anna Pugliese. (2022) Therapeutic Potential of Highly Selective A3 Adenosine Receptor Ligands in the Central and Peripheral Nervous System. Molecules 27:6, pages 1890.
Crossref
Fazhi Yu, Chenyu Zhu, Shuyin Ze, Haojie Wang, Xinyu Yang, Mingyao Liu, Qiong Xie, Weiqiang Lu & Yonghui Wang. (2022) Design, Synthesis, and Bioevaluation of 2-Aminopteridin-7(8 H )-one Derivatives as Novel Potent Adenosine A 2A Receptor Antagonists for Cancer Immunotherapy . Journal of Medicinal Chemistry 65:5, pages 4367-4386.
Crossref
Giulia Pozzi, Giuliana Gobbi, Elena Masselli, Cecilia Carubbi, Valentina Presta, Luca Ambrosini, Marco Vitale & Prisco Mirandola. (2022) Buffering Adaptive Immunity by Hydrogen Sulfide. Cells 11:3, pages 325.
Crossref
Anjali Saini, Rajiv Patel, Sobhi Gaba, Gurpreet Singh, G.D. Gupta & Vikramdeep Monga. (2022) Adenosine receptor antagonists: Recent advances and therapeutic perspective. European Journal of Medicinal Chemistry 227, pages 113907.
Crossref
Zhao Zhang, Yongbo Yu, Pengfei Zhang, Guofeng Ma, Mingxin Zhang, Ye Liang, Wei Jiao & Haitao Niu. (2021) Identification of NTRK3 as a potential prognostic biomarker associated with tumor mutation burden and immune infiltration in bladder cancer. BMC Cancer 21:1.
Crossref
Rafael Franco, Rafael Rivas-Santisteban, Gemma Navarro & Irene Reyes-Resina. (2021) Adenosine Receptor Antagonists to Combat Cancer and to Boost Anti-Cancer Chemotherapy and Immunotherapy. Cells 10:11, pages 2831.
Crossref
Suming Pan, Sixian Liang & Xianyan Wang. (2021) ADORA1 promotes nasopharyngeal carcinoma cell progression through regulation of PI3K/AKT/GSK-3β/β-catenin signaling. Life Sciences 278, pages 119581.
Crossref
G. Lakshma Reddy, Rupam Sarma, Shuhao Liu, Weifeng Huang, Jinping Lei, Jiasheng Fu & Wenhao Hu. (2021) Design, synthesis and biological evaluation of novel scaffold benzo[4,5]imidazo [1,2-a]pyrazin-1-amine: Towards adenosine A2A receptor (A2A AR) antagonist. European Journal of Medicinal Chemistry 210, pages 113040.
Crossref
Fabrizio Vincenzi, Silvia Pasquini, Pier Andrea Borea & Katia Varani. (2020) Targeting Adenosine Receptors: A Potential Pharmacological Avenue for Acute and Chronic Pain. International Journal of Molecular Sciences 21:22, pages 8710.
Crossref
Fazhi Yu, Chenyu Zhu, Qiong Xie & Yonghui Wang. (2020) Adenosine A 2A Receptor Antagonists for Cancer Immunotherapy . Journal of Medicinal Chemistry 63:21, pages 12196-12212.
Crossref
Costanza Ceni, Daniela Catarzi, Flavia Varano, Diego Dal Ben, Gabriella Marucci, Michela Buccioni, Rosaria Volpini, Andrea Angeli, Alessio Nocentini, Paola Gratteri, Claudiu T. Supuran & Vittoria Colotta. (2020) Discovery of first-in-class multi-target adenosine A2A receptor antagonists-carbonic anhydrase IX and XII inhibitors. 8-Amino-6-aryl-2-phenyl-1,2,4-triazolo [4,3-a]pyrazin-3-one derivatives as new potential antitumor agents. European Journal of Medicinal Chemistry 201, pages 112478.
Crossref
Flavia Varano, Daniela Catarzi, Erica Vigiani, Fabrizio Vincenzi, Silvia Pasquini, Katia Varani & Vittoria Colotta. (2020) Piperazine- and Piperidine-Containing Thiazolo[5,4-d]pyrimidine Derivatives as New Potent and Selective Adenosine A2A Receptor Inverse Agonists. Pharmaceuticals 13:8, pages 161.
Crossref
Flavia Varano, Daniela Catarzi, Fabrizio Vincenzi, Silvia Pasquini, Julie Pelletier, Juliana Lopes Rangel Fietto, Nicolly Espindola Gelsleichter, Marine Sarlandie, Audrey Guilbaud, Jean Sévigny, Katia Varani & Vittoria Colotta. (2020) Structural investigation on thiazolo[5,4-d]pyrimidines to obtain dual-acting blockers of CD73 and adenosine A2A receptor as potential antitumor agents. Bioorganic & Medicinal Chemistry Letters 30:9, pages 127067.
Crossref
Jiří Voller, Tibor Béres, Marek Zatloukal, Petr Džubák, Marián Hajdúch, Karel Doležal, Thomas Schmülling & Strnad Miroslav. (2019) Anti-cancer activities of cytokinin ribosides. Phytochemistry Reviews 18:4, pages 1101-1113.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.