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Expert Review of Anticancer Therapy Volume 18, 2018 - Issue 10
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Review

Therapeutic approaches for T790M mutation positive non-small-cell lung cancer

Ilaria AttiliDepartment of Surgical, Oncological and Gastroenterological Sciences, University of Padova, Padova, ItalyView further author information
,
Niki KarachaliouInstituto Oncológico Dr Rosell (IOR), University Hospital Sagrat Cor, Barcelona, Spain;Coyote Research Group, Pangaea Oncology, Laboratory of Molecular Biology, Quirón-Dexeus University Institute, Barcelona, SpainView further author information
,
PierFranco ConteDepartment of Surgical, Oncological and Gastroenterological Sciences, University of Padova, Padova, ItalyView further author information
,
Laura BonannoMedical Oncology 2, Istituto Oncologico Veneto, IRCCS, Padova, ItalyView further author information
&
Rafael RosellCoyote Research Group, Pangaea Oncology, Laboratory of Molecular Biology, Quirón-Dexeus University Institute, Barcelona, Spain;Institut d’Investigació en Ciències Germans Trias i Pujol, Badalona, Spain;Instituto Oncológico Dr Rosell (IOR), Quirón-Dexeus University Institute, Barcelona, Spain;Institut Català d’Oncologia, Hospital Germans Trias i Pujol, Badalona, SpainCorrespondence[email protected]
View further author information
Pages 1021-1030 | Received 23 Feb 2018, Accepted 02 Aug 2018, Published online: 14 Aug 2018

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Amit Singh & Abha Mishra. (2023) Investigation of molecular mechanism leading to gefitinib and osimertinib resistance against EGFR tyrosine kinase: molecular dynamics and binding free energy calculation. Journal of Biomolecular Structure and Dynamics 41:10, pages 4534-4548.
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Shannon S Zhang & Sai-hong Ignatius Ou. (2022) Spotlight on Furmonertinib (Alflutinib, AST2818). The Swiss Army Knife (del19, L858R, T790M, Exon 20 Insertions, “uncommon-G719X, S768I, L861Q”) Among the Third-Generation EGFR TKIs?. Lung Cancer: Targets and Therapy 13, pages 67-73.
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Amit Singh, Ravi Saini & Abha Mishra. (2022) Novel allosteric inhibitor to target drug resistance in EGFR mutant: molecular modelling and free energy approach. Molecular Simulation 48:9, pages 801-811.
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Xuejuan Gao, Yanfeng Zhao, Yi Bao, Wei Yin, Liyu Liu, Ruchuan Liu, Zhengquan Yu, Xiao Zhou & Jianwei Shuai. (2019) Poor Prognosis With Coexistence Of EGFR T790M Mutation And Common EGFR-Activating Mutation In Non- Small Cell Lung Cancer. Cancer Management and Research 11, pages 9621-9630.
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