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Expert Review of Anticancer Therapy Volume 22, 2022 - Issue 4
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Review

Lenvatinib dose, efficacy, and safety in the treatment of multiple malignancies

Robert J. Motzera Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical Center, New York, NY, USACorrespondence[email protected]
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,
Matthew H. Taylorb Division of Hematology and Oncology, Earle A. Chiles Research Institute, Providence Portland Medical Center, Portland, OR, USAView further author information
,
Thomas R. Jeffry Evansc Institute of Cancer Sciences, University of Glasgow, Glasgow, UK;d Medical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UKView further author information
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Takuji Okusakae Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital, Tokyo, JapanView further author information
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Hilary Glend Medical Oncology, Beatson West of Scotland Cancer Centre, Glasgow, UKView further author information
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Gregory M. Lubinieckif Global Clinical Development, Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USAView further author information
,
Corina Dutcusg Clinical Research, Eisai Inc., Nutley, NJ, USAView further author information
,
Alan D. Smithg Clinical Research, Eisai Inc., Nutley, NJ, USAView further author information
,
Chinyere E. Okparag Clinical Research, Eisai Inc., Nutley, NJ, USAView further author information
,
Ziad Husseinh Clinical Pharmacology Science, Eisai Europe Ltd, Hatfield, UKView further author information
,
Seiichi Hayatoi Clinical Pharmacology Science, Eisai Co., Ltd, Tokyo, JapanView further author information
,
Toshiyuki Tamaij Clinical Research, Eisai Co., Ltd, Tokyo, JapanView further author information
&
Vicky Makkera Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical Center, New York, NY, USAView further author information
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Pages 383-400 | Received 23 Dec 2021, Accepted 03 Feb 2022, Published online: 07 Apr 2022

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Amin Ramezani, Mohammadrasul Zareinejad, Elham Mahmoudi Maymand, Elina Kaviani & Abbas Ghaderi. (2023) Production of a biosimilar version of aflibercept to improve VEGF blocker cytotoxicity on endothelial cells. Growth Factors 41:3, pages 140-151.
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Christopher A. Walker, Alexandra N. Spirtos & David S. Miller. (2023) Pembrolizumab plus lenvatinib combination therapy for advanced endometrial carcinoma. Expert Review of Anticancer Therapy 23:4, pages 361-368.
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Articles from other publishers (4)

Robert Motzer, Saby George, Jaime R Merchan, Thomas E Hutson, Xun Song, Rodolfo F Perini, Ran Xie, Urmi Bapat & Javier Puente. (2023) Characterization and Management of Adverse Reactions From the CLEAR Study in Advanced Renal Cell Carcinoma Treated With Lenvatinib Plus Pembrolizumab. The Oncologist 28:6, pages 501-509.
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Zheng Jing, Tomohiro Iba, Hisamichi Naito, Pingping Xu, Jun-ichi Morishige, Naoto Nagata, Hironao Okubo & Hitoshi Ando. (2023) L-carnitine prevents lenvatinib-induced muscle toxicity without impairment of the anti-angiogenic efficacy. Frontiers in Pharmacology 14.
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Noriaki Sunaga, Yosuke Miura, Reiko Sakurai, Sohei Ohshima, Shogo Uno, Sohei Muto, Mari Sato, Hiroaki Tsurumaki, Masakiyo Yatomi, Yasuhiko Koga, Yoichi Ohtaki, Toshiteru Nagashima, Naoko Okano, Nobuteru Kubo, Toshitaka Maeno & Takeshi Hisada. (2023) Sustained antitumor response to lenvatinib with weekend-off and alternate-day administration in chemotherapy-refractory thymic carcinoma: a case report. Anti-Cancer Drugs 34:4, pages 605-608.
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Laurys Boudin, Jean-Baptiste Morvan, Juliette Thariat, Denis Métivier, Pierre-Yves Marcy & David Delarbre. (2022) Rationale Efficacy and Safety Evidence of Lenvatinib and Pembrolizumab Association in Anaplastic Thyroid Carcinoma. Current Oncology 29:10, pages 7718-7731.
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