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Is physical exercise a multiple sclerosis disease modifying treatment?

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Pages 951-960 | Received 28 Mar 2016, Accepted 12 May 2016, Published online: 08 Jun 2016

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Luis Andreu-Caravaca, Domingo J. Ramos-Campo, Linda H. Chung, Alejandro Martínez-Rodríguez & Jacobo Á. Rubio-Arias. (2023) Effects and optimal dosage of resistance training on strength, functional capacity, balance, general health perception, and fatigue in people with multiple sclerosis: a systematic review and meta-analysis. Disability and Rehabilitation 45:10, pages 1595-1607.
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Brynn Adamson, Dominique Kinnett-Hopkins, Nikta Athari Anaraki & Emerson Sebastião. (2022) The experiences of inaccessibility and ableism related to physical activity: a photo elicitation study among individuals with multiple sclerosis. Disability and Rehabilitation 44:12, pages 2648-2659.
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Claudia H. Marck, Yvonne C. Learmonth, Jing Chen & Ingrid van der Mei. (2022) Physical activity, sitting time and exercise types, and associations with symptoms in Australian people with multiple sclerosis. Disability and Rehabilitation 44:8, pages 1380-1388.
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Emma V. Richardson, Elizabeth Barstow & Robert W. Motl. (2022) Exercise experiences among persons with multiple sclerosis living in the southeast of the United States. Disability and Rehabilitation 44:1, pages 79-87.
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Robert W. Motl & Brian M. Sandroff. (2020) Current perspectives on exercise training in the management of multiple sclerosis. Expert Review of Neurotherapeutics 20:8, pages 855-865.
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Emma V. Richardson, Elizabeth A. Barstow & Robert W. Motl. (2019) A narrative exploration of the evolving perception of exercise among people with multiple sclerosis. Qualitative Research in Sport, Exercise and Health 11:1, pages 119-137.
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Elizabeth Morghen Sikes, Robert W Motl & Jayne M Ness. (2018) Pediatric multiple sclerosis: current perspectives on health behaviors. Pediatric Health, Medicine and Therapeutics 9, pages 17-25.
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Brynn C. Adamson, Matthew D. Adamson, Melissa M. Littlefield & Robert W. Motl. (2018) ‘Move it or lose it’: perceptions of the impact of physical activity on multiple sclerosis symptoms, relapse and disability identity. Qualitative Research in Sport, Exercise and Health 10:4, pages 457-475.
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Laura Papetti, Elena Panella, Gabriele Monte, Michela Ada Noris Ferilli, Samuela Tarantino, Martina Proietti Checchi & Massimiliano Valeriani. (2023) Pediatric Onset Multiple Sclerosis and Obesity: Defining the Silhouette of Disease Features in Overweight Patients. Nutrients 15:23, pages 4880.
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Robert W Motl, Blathin Casey, Yvonne Charlotte Learmonth, Amy Latimer-Cheung, Dominique L Kinnett-Hopkins, Claudia H Marck, Johannes Carl, Klaus Pfeifer, Karin Riemann-Lorenz, Christoph Heesen & Susan Coote. (2023) The MoXFo initiative – adherence: Exercise adherence, compliance and sustainability among people with multiple sclerosis: An overview and roadmap for research. Multiple Sclerosis Journal 29:13, pages 1595-1603.
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Brynn Adamson, Nic Wyatt, Latashia Key, Carrena Boone & Robert W. Motl. (2023) Results of the MOVE MS Program: A Feasibility Study on Group Exercise for Individuals with Multiple Sclerosis. International Journal of Environmental Research and Public Health 20:16, pages 6567.
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David S. Younger. 2023. Motor System Disorders, Part II: Spinal Cord, Neurodegenerative, and Cerebral Disorders and Treatment. Motor System Disorders, Part II: Spinal Cord, Neurodegenerative, and Cerebral Disorders and Treatment 119 147 .
Luana Gilio, Diego Fresegna, Antonietta Gentile, Livia Guadalupi, Krizia Sanna, Francesca De Vito, Sara Balletta, Silvia Caioli, Francesca Romana Rizzo, Alessandra Musella, Ennio Iezzi, Alessandro Moscatelli, Giovanni Galifi, Roberta Fantozzi, Paolo Bellantonio, Roberto Furlan, Annamaria Finardi, Valentina Vanni, Ettore Dolcetti, Antonio Bruno, Fabio Buttari, Georgia Mandolesi, Diego Centonze & Mario Stampanoni Bassi. (2022) Preventive exercise attenuates IL-2-driven mood disorders in multiple sclerosis. Neurobiology of Disease 172, pages 105817.
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Abhi Shah, Viraj Panchal, Kashyap Patel, Zainab Alimohamed, Nirja Kaka, Yashendra Sethi & Neil Patel. (2022) Pathogenesis and management of multiple sclerosis revisited. Disease-a-Month, pages 101497.
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Katie L.J. Cederberg, Morgan L. Schuetz, Brianna Mathison & Robert W. Motl. (2022) Restless legs syndrome severity associated with reduced physical function in adults with multiple sclerosis. Gait & Posture 97, pages 56-61.
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Robert W Motl & Brian M Sandroff. (2022) Physical exercise in multiple sclerosis is not just a symptomatic therapy: It has a disease-modifying effect—Yes. Multiple Sclerosis Journal 28:6, pages 859-861.
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Thomas Edwards, Anne Sophie Michelsen, Afolasade O. Fakolade, Ulrik Dalgas & Lara A. Pilutti. (2022) Exercise training improves participation in persons with multiple sclerosis: A systematic review and meta-analysis. Journal of Sport and Health Science 11:3, pages 393-402.
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Zuzanna Kuczynska, Erkan Metin, Michal Liput & Leonora Buzanska. (2021) Covering the Role of PGC-1α in the Nervous System. Cells 11:1, pages 111.
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Moira Smith, Bridee Neibling, Gavin Williams, Melanie Birks & Ruth Barker. (2021) Consumer experience of a flexible exercise participation program (FEPP) for individuals with multiple sclerosis: A mixed‐methods study. Physiotherapy Research International 26:4.
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L. Declerck, G. Stoquart, T. Lejeune, M. Vanderthommen & J.-F. Kaux. (2021) Barriers to development and expansion of adaptive physical activity and sports for individuals with a physical disability in sports clubs and centres. Science & Sports 36:3, pages 202-209.
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Johannes Carl, Gorden Sudeck & Klaus Pfeifer. (2020) Competencies for a Healthy Physically Active Lifestyle: Second-Order Analysis and Multidimensional Scaling. Frontiers in Psychology 11.
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Shane Chanpimol, Kimberly Benson, Heidi Maloni, Susan Conroy & Mitchell Wallin. (2020) Acceptability and outcomes of an individualized exergaming telePT program for veterans with multiple sclerosis: a pilot study. Archives of Physiotherapy 10:1.
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Patricia J. Manns, Golnoush Mehrabani, Sarah Norton, Saeideh Aminian & Robert W. Motl. (2020) The SitLess With MS Program: Intervention Feasibility and Change in Sedentary Behavior. Archives of Rehabilitation Research and Clinical Translation 2:4, pages 100083.
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Brian M. Sandroff, C. Danielle Jones, Jessica F. Baird & Robert W. Motl. (2020) Systematic Review on Exercise Training as a Neuroplasticity-Inducing Behavior in Multiple Sclerosis. Neurorehabilitation and Neural Repair 34:7, pages 575-588.
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Diego Centonze, Letizia Leocani & Peter Feys. (2020) Advances in physical rehabilitation of multiple sclerosis. Current Opinion in Neurology 33:3, pages 255-261.
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Robert W. Motl, Katie L. Cederberg & Brian M. Sandroff. 2020. Handbook of Sport Psychology. Handbook of Sport Psychology 857 871 .
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Motahare Mokhtarzade, Hamid Agha-Alinejad, Robert W. Motl, Raoof Negaresh, Julien S. Baker & Philipp Zimmer. (2019) Weight control and physical exercise in people with multiple sclerosis: Current knowledge and future perspectives. Complementary Therapies in Medicine 43, pages 240-246.
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Victor W. Mark, Edward Taub, Gitendra Uswatte, David M. Morris, Gary R. Cutter, Terrie L. Adams, Mary H. Bowman & Staci McKay. (2018) Phase II Randomized Controlled Trial of Constraint-Induced Movement Therapy in Multiple Sclerosis. Part 1: Effects on Real-World Function. Neurorehabilitation and Neural Repair 32:3, pages 223-232.
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Robert W. Motl & Brian M. Sandroff. (2018) Exercise as a Countermeasure to Declining Central Nervous System Function in Multiple Sclerosis. Clinical Therapeutics 40:1, pages 16-25.
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