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Review

Emerging therapies in Huntington’s disease

Pages 983-995 | Received 01 Apr 2019, Accepted 10 Jun 2019, Published online: 17 Jun 2019

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Sumit Jamwal, John D Elsworth, Vikrant Rahi & Puneet Kumar. (2020) Gene therapy and immunotherapy as promising strategies to combat Huntington’s disease-associated neurodegeneration: emphasis on recent updates and future perspectives. Expert Review of Neurotherapeutics 20:11, pages 1123-1141.
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Md. Rezaul Islam, Maruf Hossain Jony, Gazi Kaifeara Thufa, Shopnil Akash, Puja Sutra Dhar, Md. Mominur Rahman, Tahmina Afroz, Muniruddin Ahmed, Hassan A. Hemeg, Abdur Rauf, Muthu Thiruvengadam & Baskar Venkidasamy. (2023) A clinical study and future prospects for bioactive compounds and semi-synthetic molecules in the therapies for Huntington's disease. Molecular Neurobiology.
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Pei Teng Lum, Mahendran Sekar, Lay Jing Seow, Mohd Farooq Shaikh, Alina Arulsamy, Thaarvena Retinasamy, Siew Hua Gan, Charles Gnanaraj, Norhaizan Mohd Esa, Gobinath Ramachawolran, Vetriselvan Subramaniyan, Suresh V. Chinni & Yuan Seng Wu. (2023) Neuroprotective potency of mangiferin against 3-nitropropionic acid induced Huntington’s disease-like symptoms in rats: possible antioxidant and anti-inflammatory mechanisms. Frontiers in Pharmacology 14.
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S. S. Rohiwal, T. D. Nguyen, E. Kamenna, J. Klima, M. Vaskovicova, D. Sekac, M. Slouf, E. Pavlova, P. Stepanek, D. Babuka, H. Benes, O. Pop-Georgievski, P. Ecorchard, P. Bezdicka, D. Smrzova, K. Stieger & Z. Ellederova. (2023) Iron Oxide Nanoparticle-Mediated siRNA Delivery System for Huntington’s Disease Treatment. ACS Applied Nano Materials 6:7, pages 5106-5116.
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Emanuele Morena, Carmela Romano, Martina Marconi, Selene Diamant, Maria Chiara Buscarinu, Gianmarco Bellucci, Silvia Romano, Daniela Scarabino, Marco Salvetti & Giovanni Ristori. (2023) Peripheral Biomarkers in Manifest and Premanifest Huntington’s Disease. International Journal of Molecular Sciences 24:7, pages 6051.
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Meysam Dehghan, Fatemeh Fathinejad, Mohammad Hosein Farzaei & Ebrahim Barzegari. (2022) In silico unraveling of molecular anti-neurodegenerative profile of Citrus medica flavonoids against novel pharmaceutical targets. Chemical Papers 77:1, pages 595-610.
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Hanadi Ananbeh, Jaromir Novak, Stefan Juhas, Jana Juhasova, Jiri Klempir, Kristyna Doleckova, Irena Rysankova, Karolina Turnovcova, Jaroslav Hanus, Hana Hansikova, Petr Vodicka & Helena Kupcova Skalnikova. (2022) Huntingtin Co-Isolates with Small Extracellular Vesicles from Blood Plasma of TgHD and KI-HD Pig Models of Huntington’s Disease and Human Blood Plasma. International Journal of Molecular Sciences 23:10, pages 5598.
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Harvey S. Singer, Jonathan W. Mink, Donald L. Gilbert & Joseph Jankovic. 2022. Movement Disorders in Childhood. Movement Disorders in Childhood 183 228 .
Hidetoshi Komatsu. (2021) Innovative Therapeutic Approaches for Huntington’s Disease: From Nucleic Acids to GPCR-Targeting Small Molecules. Frontiers in Cellular Neuroscience 15.
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Pubu M. Abeyasinghe, Jeffrey D. Long, Adeel Razi, Dorian Pustina, Jane S. Paulsen, Sarah J. Tabrizi, Govinda R. Poudel & Nellie Georgiou‐Karistianis. (2021) Tracking Huntingtonʼs Disease Progression Using Motor, Functional, Cognitive, and Imaging Markers. Movement Disorders 36:10, pages 2282-2292.
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Shirel Argueti-Ostrovsky, Leenor Alfahel, Joy Kahn & Adrian Israelson. (2021) All Roads Lead to Rome: Different Molecular Players Converge to Common Toxic Pathways in Neurodegeneration. Cells 10:9, pages 2438.
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Filipa Júlio, Ruth Blanco, Josè Perez Casanova, Barbara D’Alessio, Beatrice De Schepper, Dina De Sousa, Paul De Sousa, Cristina Ferreira, Hans Gommans, Rob Haselberg, Emilie Hermant, Danuta Lis, Sabrina Maffi, Svein Olaf Olsen, Marios Papantoniou, Ferdinando Squitieri, Marina Tretyakova, Zaynab Umakhanova, Vladimír Václavík, Michaela Winkelmann & Astri Arnesen. (2021) Perceptions about Research Participation among Individuals at Risk and Individuals with Premanifest Huntington’s Disease: A Survey Conducted by the European Huntington Association. Journal of Personalized Medicine 11:8, pages 815.
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Hanadi Ananbeh, Petr Vodicka & Helena Kupcova Skalnikova. (2021) Emerging Roles of Exosomes in Huntington’s Disease. International Journal of Molecular Sciences 22:8, pages 4085.
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Pei Teng Lum, Mahendran Sekar, Siew Hua Gan, Srinivasa Reddy Bonam & Mohd. Farooq Shaikh. (2021) Protective Effect of Natural Products against Huntington’s Disease: An Overview of Scientific Evidence and Understanding Their Mechanism of Action. ACS Chemical Neuroscience 12:3, pages 391-418.
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Samuel Morales-Navarro, Luis Prent-Peñaloza, Yeray A. Rodríguez Núñez, Laura Sánchez-Aros, Oscar Forero-Doria, Wendy González, Nuria E. Campilllo, Miguel Reyes-Parada, Ana Martínez & David Ramírez. (2019) Theoretical and Experimental Approaches Aimed at Drug Design Targeting Neurodegenerative Diseases. Processes 7:12, pages 940.
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