Optimizing levodopa therapy, when and how? Perspectives on the importance of delivery and the potential for an early combination approach

Andrew Leesa University College London, Reta Lila Weston Institute, London, UKCorrespondence[email protected]
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Eduardo Tolosab Parkinson disease and Movement Disorders Unit, Neurology Service, Hospital Clinic de Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED: CB06/05/0018-ISCIII) Barcelona, Barcelona, SpainView further author information

Fabrizio Stocchic Department of Neurology, University San Raffaele and IRCCS San Raffaele Pisana, Rome, ItalyView further author information

Joaquim J. Ferreirad Laboratory of Clinical Pharmacology and Therapeutics, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal;e CNS – Campus Neurológico, Torres Vedras, Portugal

https://orcid.org/0000-0003-3950-5113 View further author information

Olivier Rascolf Department of Neurosciences and Clinical Pharmacology, Clinical Investigation center CIC1436 and NS-Park/FCRIN network; University Hospital of Toulouse, INSERM and University of Toulouse 3, Toulouse, FranceView further author information

Angelo Antoninig Movement Disorders Unit, Study Center for Neurodegenerative Diseases (CESNE), Department of Neuroscience, University of PadovaView further author information

Werner Poeweh Department of Neurology, Medical University of Innsbruck, Innsbruck, AustriaView further author information

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Optimizing levodopa therapy, when and how? Perspectives on the importance of delivery and the potential for an early combination approach

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Optimizing levodopa therapy, when and how? Perspectives on the importance of delivery and the potential for an early combination approach

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