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Expert Opinion on Drug Safety Volume 15, 2016 - Issue 12
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Review

No meaningful association between suicidal behavior and the use of IL-17A-neutralizing or IL-17RA-blocking agents

Andrea ChiricozziDermatology Department, University of Pisa, Pisa, ItalyCorrespondence[email protected]
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,
Marco RomanelliDermatology Department, University of Pisa, Pisa, ItalyView further author information
,
Rosita SaracenoDermatology Department, University of Tor Vergata, Rome, ItalyView further author information
&
Tiago TorresDepartment of Dermatology, Centro Hospitalar do Porto and Instituto de Ciências Biomédicas Abel Salazar, University of Porto, Porto, PortugalView further author information
Pages 1653-1659 | Received 02 Aug 2016, Accepted 19 Aug 2016, Published online: 31 Aug 2016

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Angelo Ruggiero, Matteo Megna, Gabriella Fabbrocini, Luigi Fornaro & Alessia Villani. (2022) Drug safety evaluation of ixekizumab for psoriasis: a review of the current knowledge. Expert Opinion on Drug Safety 21:10, pages 1249-1257.
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Helena Iznardo & Lluís Puig. (2020) The safety of brodalumab for the treatment of psoriasis. Expert Opinion on Drug Safety 19:4, pages 365-372.
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Roberta Di Caprio, Giuseppina Caiazzo, Sara Cacciapuoti, Gabriella Fabbrocini, Emanuele Scala & Anna Balato. (2020) Safety concerns with current treatments for psoriasis in the elderly. Expert Opinion on Drug Safety 19:4, pages 523-531.
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Maria Esposito, Alessandro Giunta, Ester Del Duca, Valeria Manfreda, Alfonso Troisi, Luca Bianchi & Maria Concetta Fargnoli. (2020) Long-term safety and efficacy of secukinumab in patients with psoriasis and major psychiatric disorders: a case series. Postgraduate Medicine 132:2, pages 172-175.
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Lluís Puig. (2020) The safety of ixekizumab in psoriasis drug therapy. Expert Opinion on Drug Safety 19:2, pages 117-130.
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Andreas Pinter, Bernd Bonnekoh, Ina Marion Hadshiew & Sebastian Zimmer. (2019) Brodalumab for the treatment of moderate-to-severe psoriasis: case series and literature review. Clinical, Cosmetic and Investigational Dermatology 12, pages 509-517.
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M Galluzzo, S D’Adamio, A Massaro, A Piccolo, L Bianchi & M Talamonti. (2019) Spotlight on brodalumab in the treatment of plaque psoriasis: the evidence to date. Clinical, Cosmetic and Investigational Dermatology 12, pages 311-321.
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Karen Ly, Mary P. Smith, Quinn Thibodeaux, Vidhatha Reddy, Wilson Liao & Tina Bhutani. (2019) Anti IL-17 in psoriasis. Expert Review of Clinical Immunology 15:11, pages 1185-1194.
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Christoffer Blegvad, Lone Skov & Claus Zachariae. (2019) Ixekizumab for the treatment of psoriasis: an update on new data since first approval. Expert Review of Clinical Immunology 15:2, pages 111-121.
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Annika Silfvast-Kaiser, So Yeon Paek & Alan Menter. (2019) Anti-IL17 therapies for psoriasis. Expert Opinion on Biological Therapy 19:1, pages 45-54.
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Nilesh Kodali, Isabella Blanchard, Sruthi Kunamneni & Mark G. Lebwohl. (2023) Current management of generalized pustular psoriasis. Experimental Dermatology 32:8, pages 1204-1218.
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Giacomo Cozzi, Laura Scagnellato, Mariagrazia Lorenzin, Edoardo Savarino, Fabiana Zingone, Francesca Ometto, Marta Favero, Andrea Doria, Stephan R. Vavricka & Roberta Ramonda. (2023) Spondyloarthritis with inflammatory bowel disease: the latest on biologic and targeted therapies. Nature Reviews Rheumatology 19:8, pages 503-518.
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Carmen Schiweck, Mareike Aichholzer, Andreas Reif & Sharmili Edwin Thanarajah. (2023) Targeting IL-17A signaling in suicidality, promise or the long arm of coincidence? Evidence in psychiatric populations revisited. Journal of Affective Disorders Reports 11, pages 100454.
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Yuxiong Jiang, Youdong Chen, Qian Yu & Yuling Shi. (2023) Biologic and Small-Molecule Therapies for Moderate-to-Severe Psoriasis: Focus on Psoriasis Comorbidities. BioDrugs 37:1, pages 35-55.
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Tiffany C. Taylor, Yang Li, De-Dong Li, Saikat Majumder, Mandy J. McGeachy, Partha S. Biswas, Sebastien Gingras & Sarah L. Gaffen. (2022) Arid5a Mediates an IL-17–Dependent Pathway That Drives Autoimmunity but Not Antifungal Host Defense. The Journal of Immunology 209:6, pages 1138-1145.
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Andrea Francesca Salvador, Kalil Alves de Lima & Jonathan Kipnis. (2021) Neuromodulation by the immune system: a focus on cytokines. Nature Reviews Immunology 21:8, pages 526-541.
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Seong Jun Seo, Bong Seok Shin, Joo‐Heung Lee & Haeyoun Jeong. (2020) Efficacy and safety of brodalumab in the Korean population for the treatment of moderate to severe plaque psoriasis: A randomized, phase III, double‐blind, placebo‐controlled study. The Journal of Dermatology 48:6, pages 807-817.
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Annika S. Silfvast-Kaiser, Dario Kivelevitch, So Yeon Paek & Alan Menter. 2021. Advances in Psoriasis. Advances in Psoriasis 263 278 .
Estela María Malatesta & María Andrea Sánchez del Río. (2020) Could Suicide Be Fostered Through the Potential Antidepressant Mechanism of Biological Agents? A Psychodermatological Approach to Existing Bibliography. Journal of Psoriasis and Psoriatic Arthritis 5:2, pages 46-51.
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Ana Stanescu, Alexandra Totan, Daniela Mircescu, Smaranda Diaconescu, Ovidiu Bratu, L�szl� Fekete, Gyula Fekete, Daniel Boda & Camelia Diaconu. (2019) Assessment of suicidal behavior in dermatology (Review). Experimental and Therapeutic Medicine.
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Sydney E. Liang, Jeffrey M. Cohen & Roger S. Ho. (2019) Psoriasis and suicidality: A review of the literature. Dermatologic Therapy 32:1, pages e12771.
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Andrew Blauvelt & Andrea Chiricozzi. (2018) The Immunologic Role of IL-17 in Psoriasis and Psoriatic Arthritis Pathogenesis. Clinical Reviews in Allergy & Immunology 55:3, pages 379-390.
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M.J. Gooderham, K.A. Papp & C.W. Lynde. (2018) Shifting the focus - the primary role of IL-23 in psoriasis and other inflammatory disorders. Journal of the European Academy of Dermatology and Venereology 32:7, pages 1111-1119.
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Kenneth F Baker & John D Isaacs. (2018) Novel therapies for immune-mediated inflammatory diseases: What can we learn from their use in rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, psoriasis, Crohn’s disease and ulcerative colitis?. Annals of the Rheumatic Diseases 77:2, pages 175-187.
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Bruce Strober, Melinda Gooderham, Elke M.G.J. de Jong, Alexa B. Kimball, Richard G. Langley, Nikita Lakdawala, Kavitha Goyal, Fabio Lawson, Wayne Langholff, Lori Hopkins, Steve Fakharzadeh, Bhaskar Srivastava & Alan Menter. (2018) Depressive symptoms, depression, and the effect of biologic therapy among patients in Psoriasis Longitudinal Assessment and Registry (PSOLAR). Journal of the American Academy of Dermatology 78:1, pages 70-80.
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Mark G. Lebwohl, Kim A. Papp, Lauren B. Marangell, John Koo, Andrew Blauvelt, Melinda Gooderham, Jashin J. Wu, Shipra Rastogi, Susan Harris, Radhakrishnan Pillai & Robert J. Israel. (2018) Psychiatric adverse events during treatment with brodalumab: Analysis of psoriasis clinical trials. Journal of the American Academy of Dermatology 78:1, pages 81-89.e5.
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Robert E. Kalb. 2018. Biologic and Systemic Agents in Dermatology. Biologic and Systemic Agents in Dermatology 73 82 .
Jillian Frieder, Dario Kivelevitch, Isabel Haugh, Ian Watson & Alan Menter. (2018) Anti-IL-23 and Anti-IL-17 Biologic Agents for the Treatment of Immune-Mediated Inflammatory Conditions. Clinical Pharmacology & Therapeutics 103:1, pages 88-101.
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Omid Roostaeyan, Dario Kivelevitch & Alan Menter. (2017) A review article on brodalumab in the treatment of moderate-to-severe plaque psoriasis. Immunotherapy 9:12, pages 963-978.
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Florian C. Kurschus & Sonja Moos. (2017) IL-17 for therapy. Journal of Dermatological Science 87:3, pages 221-227.
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Jose-Manuel Carrascosa. (2017) Nuevos tratamientos en psoriasis. Medicina Clínica 149:4, pages 157-159.
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Jose-Manuel Carrascosa. (2017) New treatments in psoriasis. Medicina Clínica (English Edition) 149:4, pages 157-159.
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Caleb Jeon, Sahil Sekhon, Mio Nakamura, Jashin J. Wu & John Koo. (2017) Psoriasis and Depression: A Comprehensive Review for Clinicians. Journal of Psoriasis and Psoriatic Arthritis 2:3, pages 47-56.
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Adriane A Levin & Jeffrey M Sobell. (2017) Update on IL-17 Inhibitors for Psoriasis. Current Dermatology Reports 6:2, pages 121-128.
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Anna Maria Andersson, Lone Skov, Jacob P. Thyssen & Alexander Egeberg. (2017) Update on Comorbidities in Psoriasis. Current Dermatology Reports 6:2, pages 129-136.
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Lisa M. Sedger, Charani Ranasinghe, Michael F. McDermott & Parisa Asvadi. 2017. Immunotherapy - Myths, Reality, Ideas, Future. Immunotherapy - Myths, Reality, Ideas, Future.

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