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Expert Opinion on Drug Safety Volume 16, 2017 - Issue 11
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Drug Safety Evaluation

Safety evaluation of trelagliptin in the treatment of Japanese type 2 diabetes mellitus patients

Kohei KakuDepartment of Internal Medicine, Kawasaki Medical School, Okayama, JapanCorrespondence[email protected]
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Pages 1313-1322 | Received 30 May 2017, Accepted 16 Aug 2017, Published online: 29 Aug 2017

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Haiyu Shao, Renzheng Wu, Li Cao, Haifeng Gu & Fang Chai. (2021) Trelagliptin stimulates osteoblastic differentiation by increasing runt-related transcription factor 2 (RUNX2): a therapeutic implication in osteoporosis. Bioengineered 12:1, pages 960-968.
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Qing Li, Xiaoyan Deng, Yan-Jun Xu & Lin Dong. (2023) Development of Long-Acting Dipeptidyl Peptidase-4 Inhibitors: Structural Evolution and Long-Acting Determinants. Journal of Medicinal Chemistry 66:17, pages 11593-11631.
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Shereen Mowaka, Nermeen Ashoush, Mariam M. Tadros & Bassam M. Ayoub. (2021) Investigation of Pharmacokinetic Parameters of Trelagliptin in Egyptian Volunteers Using Sensitive LC-MS/MS: A Comparative Study with a Japanese Population. Journal of Analytical Methods in Chemistry 2021, pages 1-9.
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Ryeon Heo, Mi Seon Seo, Jin Ryeol An, Minji Kang, Hongzoo Park, Eun-Taek Han, Jin-Hee Han, Wanjoo Chun & Won Sun Park. (2021) The anti-diabetic drug trelagliptin induces vasodilation via activation of Kv channels and SERCA pumps. Life Sciences 283, pages 119868.
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Deepthi Ramesh, Balaji Gowrivel Vijayakumar & Tharanikkarasu Kannan. (2020) Therapeutic potential of uracil and its derivatives in countering pathogenic and physiological disorders. European Journal of Medicinal Chemistry 207, pages 112801.
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Chen Zhang, Fei Ye, Jianmin Wang, Ping He, Ming Lei, Longbin Huang, Anbang Huang, Pingming Tang, Hongjun Lin, Yuting Liao, Yong Liang, Jia Ni & Pangke Yan. (2020) Design, Synthesis, and Evaluation of a Series of Novel Super Long-Acting DPP-4 Inhibitors for the Treatment of Type 2 Diabetes. Journal of Medicinal Chemistry 63:13, pages 7108-7126.
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Shiliang Li, Chun Qin, Shichao Cui, Hongling Xu, Fangshu Wu, Jiawei Wang, Mingbo Su, Xiaoyu Fang, Dan Li, Qian Jiao, Ming Zhang, Chunmei Xia, Lili Zhu, Rui Wang, Jia Li, Hualiang Jiang, Zhenjiang Zhao, Jingya Li & Honglin Li. (2019) Discovery of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment of Type 2 Diabetes. Journal of Medicinal Chemistry 62:5, pages 2348-2361.
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Bassam M. Ayoub, Shereen Mowaka, Marwa M. Safar, Nermeen Ashoush, Mona G. Arafa, Haidy E. Michel, Mariam M. Tadros, Mohamed M. Elmazar & Shaker A. Mousa. (2018) Repositioning of Omarigliptin as a once-weekly intranasal Anti-parkinsonian Agent. Scientific Reports 8:1.
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Shereen Mowaka, Bassam M. Ayoub, Mostafa A. Hassan & Wafaa A. Zaghary. (2018) Different Spectrophotometric Methods for Simultaneous Determination of Trelagliptin and Its Acid Degradation Product. Journal of Analytical Methods in Chemistry 2018, pages 1-7.
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