Advanced search
Publication Cover
Expert Opinion on Drug Safety Volume 18, 2019 - Issue 10
Submit an article Journal homepage
2,163
Views
33
CrossRef citations to date
0
Altmetric
Review

Risk-benefit balance assessment of SSRI antidepressant use during pregnancy and lactation based on best available evidence – an update

Céline J Fischer FumeauxClinic of Neonatology, Mother and Child department, Lausanne University Hospital, Lausanne, SwitzerlandView further author information
,
Mathilde Morisod HarariService of Child and Adolescent Psychiatry, Lausanne University Hospital, Lausanne, SwitzerlandView further author information
,
Etienne WeisskopfSchool of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Geneva, SwitzerlandView further author information
,
Chin B EapUnit of Pharmacogenetics and Clinical Psychopharmacology, Department of Psychiatry, Lausanne University Hospital, Lausanne, SwitzerlandView further author information
,
Manuella EpineyDepartment of Gynecology and Obstetrics, Geneva University Hospital, Geneva, SwitzerlandView further author information
,
Yvan VialService of Obstetrics, Mother and Child department, Lausanne University Hospital, Lausanne, SwitzerlandView further author information
,
Chantal CsajkaSchool of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Geneva, SwitzerlandView further author information
,
Myriam Bickle GrazClinic of Neonatology, Mother and Child department, Lausanne University Hospital, Lausanne, SwitzerlandView further author information
&
Alice PanchaudSchool of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Geneva, Switzerland;Pharmacy Service, Department of interdisciplinary centers, Lausanne University Hospital, Lausanne, SwitzerlandCorrespondence[email protected]
View further author information
 show all
Pages 949-963 | Received 21 Jun 2019, Accepted 19 Aug 2019, Published online: 09 Sep 2019

Citations (33)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Zhuoyue Wang, Hui Li, Yimin Kang, Yanlong Liu, Ligang Shan & Fan Wang. (2022) Risks of Digestive System Side-Effects of Selective Serotonin Reuptake Inhibitors in Patients with Depression: A Network Meta-Analysis. Therapeutics and Clinical Risk Management 18, pages 799-812.
Read now

Articles from other publishers (32)

GERRI R. BAER, RACHANA SINGH & JONATHAN M. DAVIS. 2024. Avery's Diseases of the Newborn. Avery's Diseases of the Newborn 106 122.e6 .
Vanessa M. Oddo, Crussie Moise, Lauren Welke, Beatriz Peñalver Bernabé, Pauline Maki, Mary Dawn Koenig, Lacey Pezley, Yinglin Xia & Lisa Tussing-Humphreys. (2023) Mediterranean Diet Adherence and Depressive Symptoms among a Nationally Representative Sample of Pregnant Women in the United States. The Journal of Nutrition 153:10, pages 3041-3048.
Crossref
Rafael R Domingues, Milo C Wiltbank & Laura L Hernandez. (2023) Maternal serotonin: implications for the use of selective serotonin reuptake inhibitors during gestation. Biology of Reproduction 109:1, pages 17-28.
Crossref
Chun Hung, Joe Kwun Nam Chan, Corine Sau Man Wong, Vivian Shi Cheng Fung, Krystal Chi Kei Lee & Wing Chung Chang. (2022) Antidepressant utilization patterns and predictors of treatment continuation in pregnant women: A 16-year population-based cohort. Australian & New Zealand Journal of Psychiatry 57:5, pages 686-697.
Crossref
Ana Flávia Quiarato Lozano, Mayara Silva Moura, Taís Raquel Batisoco Dinhani, Lethícia Valencise & Wilma De Grava Kempinas. (2023) Is lactational sertraline exposure safe for maternal health and the reproductive/neurobehavioral development of the descendants? A study in rats. Reproductive Toxicology 117, pages 108356.
Crossref
Kristen M Krysko, Ruth Dobson, Raed Alroughani, Maria Pia Amato, Riley Bove, Andrea I Ciplea, Yara Fragoso, Maria Houtchens, Vilija G Jokubaitis, Melinda Magyari, Azza Abdelnasser, Vasantha Padma, Sandra Thiel, Mar Tintore, Sandra Vukusic & Kerstin Hellwig. (2023) Family planning considerations in people with multiple sclerosis. The Lancet Neurology 22:4, pages 350-366.
Crossref
Ayala Gover, Kareen Endrawes, Michal Molad, Karen Lavie-Nevo & Arieh Riskin. (2023) The Effect of SSRI Exposure in Pregnancy on Early Respiratory and Metabolic Adaptation in Infants Born Preterm. Children 10:3, pages 508.
Crossref
Pierre Desaunay, Léa-Gabrielle Eude, Michel Dreyfus, Cénéric Alexandre, Sophie Fedrizzi, Joachim Alexandre, Faruk Uguz & Fabian Guénolé. (2023) Benefits and Risks of Antidepressant Drugs During Pregnancy: A Systematic Review of Meta-analyses. Pediatric Drugs.
Crossref
Anna Linda Leutritz, Lara van Braam, Katharina Preis, Andrea Gehrmann, Maike Scherf‐Clavel, Katrin Fiedler, Stefan Unterecker & Sarah Kittel‐Schneider. (2022) Psychotropic medication in pregnancy and lactation and early development of exposed children. British Journal of Clinical Pharmacology 89:2, pages 737-750.
Crossref
Julie A. Vignato, S. Banu Gumusoglu, Heather A. Davis, Sabrina M. Scroggins, Wendy S. Hamilton, Debra S. Brandt, Gary L. Pierce, Boyd A. Knosp, Donna A. Santillan & Mark K. Santillan. (2022) Selective Serotonin Reuptake Inhibitor Use in Pregnancy and Protective Mechanisms in Preeclampsia. Reproductive Sciences 30:2, pages 701-712.
Crossref
Karina Bravo, Marcelo González-Ortiz, Sebastian Beltrán-Castillo, Daniela Cáceres & Jaime Eugenín. 2023. Advances in Maternal-Fetal Biomedicine. Advances in Maternal-Fetal Biomedicine 179 198 .
Maria Muzik, Samantha Shaw, Sophie Grigoriadis, Kristina M. Deligiannidis, Angelika Wieck, Prabha S. Chandra, Manisha Murugesan, Cara Anne Poland & Nancy Renn-Bugai. 2020. Tasman’s Psychiatry. Tasman’s Psychiatry 1 37 .
Dawei Li. (2022) Treatment of depression from both biological and psychological aspects. Treatment of depression from both biological and psychological aspects.
Jeffrey Wald, Anja Henningsson, Eva Hanze, Ethan Hoffmann, Haihong Li, Helen Colquhoun & Kristina M. Deligiannidis. (2022) Allopregnanolone Concentrations in Breast Milk and Plasma from Healthy Volunteers Receiving Brexanolone Injection, With Population Pharmacokinetic Modeling of Potential Relative Infant Dose. Clinical Pharmacokinetics 61:9, pages 1307-1319.
Crossref
Rahel Baumgartner, Ursula Winterfeld, Alice Panchaud & Ana Paula Simões-Wüst. (2022) Queries on medication use during pregnancy: characterisation of the Swiss Teratogen Information Service database. Swiss Medical Weekly 152:2122, pages w30187.
Crossref
Laurel A. Copeland, Rebecca L. KinneyAimee R. Kroll-DesrosiersGeetha ShivakumarKristin M. Mattocks. (2022) Medications with Potential for Fetal Risk Prescribed to Veterans. Journal of Women's Health.
Crossref
Luke E. Grzeskowiak, Moni R. Saha, Hedvig Nordeng, Eivind Ystrom & Lisa H. Amir. (2022) Perinatal antidepressant use and breastfeeding outcomes: Findings from the Norwegian Mother, Father and Child Cohort Study. Acta Obstetricia et Gynecologica Scandinavica 101:3, pages 344-354.
Crossref
Nadia T Evans, Nicholas Williams, Varan Perananthan, William Lugg, Andrew H Dawson & David A Osborn. (2021) Neonatal serotonin toxicity. Journal of Paediatrics and Child Health 58:1, pages 189-190.
Crossref
Fiona L. Challacombe & Megan A. Jansen. 2022. Clinical Guide to Exposure Therapy. Clinical Guide to Exposure Therapy 201 218 .
Gianluca Rosso & Giuseppe Maina. 2022. Key Topics in Perinatal Mental Health. Key Topics in Perinatal Mental Health 79 92 .
Gerd Laux. 2022. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 1257 1269 .
Sarah Donald, Katrina Sharples, Dave Barson, Simon Horsburgh & Lianne Parkin. (2021) Antidepressant dispensing before, during, and after pregnancy in New Zealand, 2005‒2014. Australian and New Zealand Journal of Obstetrics and Gynaecology 61:6, pages 837-845.
Crossref
Cássio Prinholato da Silva, Denise Dias Oliveira, Bruno Iglesias Benincasa, Bruna Barbar, Ana Lúcia Facchin & Rene Oliveira Beleboni. (2021) Antidepressant activity of Riparin A in murine model. Behavioural Pharmacology 32:7, pages 599-606.
Crossref
Barbara Marie Alba. (2021) CE: Postpartum Depression: A Nurse's Guide. AJN, American Journal of Nursing 121:7, pages 32-43.
Crossref
Bin Chao, Lili Zhang, Juhua Pan, Ying Zhang, Yuxia Chen, Manman Xu & Shijing Huang. (2021) Stanniocalcin-1 Overexpression Prevents Depression-Like Behaviors Through Inhibition of the ROS/NF-κB Signaling Pathway. Frontiers in Psychiatry 12.
Crossref
Or Burstein, Noam Simon, Yaarit Simchon-Tenenbaum, Moshe Rehavi, Motty Franko, Alon Shamir & Ravid Doron. (2021) Moderation of the transgenerational transference of antenatal stress-induced anxiety. Translational Psychiatry 11:1.
Crossref
О.Р. Айзберг. (2021) Diagnosis and Treatment of Postpartum Depression. Психиатрия, психотерапия и клиническая психология:1, pages 116-123.
Crossref
Sheng-Min Wang, Won-Myong Bahk, Young Sup Woo, Jeong Seok Seo, Young-Min Park, Won Kim, Jong-Hyun Jeong, Se-Hoon Shim, Jung Goo Lee, Seung-Ho Jang, Chan-Mo Yang, Myung Hun Jung, Hyung Mo Sung, IL Han Choo, Bo-Hyun Yoon, Sang-Yeol Lee, Duk-In Jon & Kyung Joon Min. (2021) Korean Medication Algorithm Project for Depressive Disorder 2021 (IV): Female and Elderly. Journal of Korean Neuropsychiatric Association 60:4, pages 258.
Crossref
Gerd Laux. 2020. NeuroPsychopharmacotherapy. NeuroPsychopharmacotherapy 1 13 .
Sabrina I. Hanswijk, Marcia Spoelder, Ling Shan, Michel M. M. Verheij, Otto G. Muilwijk, Weizhuo Li, Chunqing Liu, Sharon M. Kolk & Judith R. Homberg. (2020) Gestational Factors throughout Fetal Neurodevelopment: The Serotonin Link. International Journal of Molecular Sciences 21:16, pages 5850.
Crossref
Neesha Hussain-Shamsy, Amika Shah, Simone N Vigod, Juveria Zaheer & Emily Seto. (2020) Mobile Health for Perinatal Depression and Anxiety: Scoping Review. Journal of Medical Internet Research 22:4, pages e17011.
Crossref
Karel Allegaert. 2020. Neurology and Pregnancy - Pathophysiology and Patient Care. Neurology and Pregnancy - Pathophysiology and Patient Care 161 178 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.