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Review

CGRP inhibitors for migraine prophylaxis: a safety review

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Pages 1237-1250 | Received 09 Jun 2020, Accepted 13 Aug 2020, Published online: 21 Sep 2020

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Cecilia Rustichelli, Rossella Avallone & Anna Ferrari. (2022) Atogepant: an emerging treatment for migraine. Expert Opinion on Pharmacotherapy 23:6, pages 653-662.
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Abimael González-Hernández, Bruno A. Marichal-Cancino & Carlos M. Villalón. (2021) The impact of CGRPergic monoclonal antibodies on prophylactic antimigraine therapy and potential adverse events. Expert Opinion on Drug Metabolism & Toxicology 17:10, pages 1223-1235.
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Bruno A. Marichal-Cancino, Abimael González-Hernández, Raquel Guerrero-Alba, Roberto Medina-Santillán & Carlos M. Villalón. (2021) A critical review of the neurovascular nature of migraine and the main mechanisms of action of prophylactic antimigraine medications. Expert Review of Neurotherapeutics 21:9, pages 1035-1050.
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Lanfranco Pellesi, Roberto De Icco, Hassan Youssef Alawie, Morten Andersen, David Liang, Sarkhan Amirguliyev, Mohammad Al-Mahdi Al-Karagholi, Faisal Mohammad Amin & Maurizio Sessa. (2021) A systematic review, meta-analysis and meta-regression evaluating the adverse reactions to erenumab in the preventive treatment of migraine. Expert Opinion on Drug Safety 20:4, pages 467-474.
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Abimael González-Hernández, Miguel Condés-Lara, Enrique García-Boll & Carlos M. Villalón. (2021) An outlook on the trigeminovascular mechanisms of action and side effects concerns of some potential neuropeptidergic antimigraine therapies. Expert Opinion on Drug Metabolism & Toxicology 17:2, pages 179-199.
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Articles from other publishers (18)

Jean Schoenen, Annelies Van Dycke, Jan Versijpt & Koen Paemeleire. (2023) Ten open questions in migraine prophylaxis with monoclonal antibodies blocking the calcitonin-gene related peptide pathway: a narrative review. The Journal of Headache and Pain 24:1.
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Anna K. Szewczyk, Samiye Ulutas, Tülin Aktürk, Linda Al-Hassany, Corinna Börner, Federica Cernigliaro, Michalis Kodounis, Salvatore Lo Cascio, David Mikolajek, Dilara Onan, Chiara Ragaglini, Susanna Ratti, Eduardo Rivera-Mancilla, Sofia Tsanoula, Rafael Villino, Karl Messlinger, Antoinette Maassen Van Den Brink & Tessa de Vries. (2023) Prolactin and oxytocin: potential targets for migraine treatment. The Journal of Headache and Pain 24:1.
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Alejandro D. Miguel-Martínez, Juan Linares-Bedolla, Belinda Villanueva-Castillo, Kristian A. Haanes, Antoinette MaassenVanDenBrink & Carlos M. Villalón. (2023) Pharmacological Profile of the Purinergic P2Y Receptors That Modulate, in Response to ADPβS, the Vasodepressor Sensory CGRPergic Outflow in Pithed Rats. Pharmaceuticals 16:3, pages 475.
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Linda Al-Hassany, Hannah S. Lyons, Deirdre M. Boucherie, Fatemeh Farham, Kristin S. Lange, Karol Marschollek, Dilara Onan, Umberto Pensato, Elisabeth Storch, Angelo Torrente, Marta Waliszewska-Prosół & Uwe Reuter. (2023) The sense of stopping migraine prophylaxis. The Journal of Headache and Pain 24:1.
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Mohammad Shafie'ei, Mohsen Farjoud Kouhanjani, Zahra Akbari, Nastaran Sarvipour, Dorsa Shekouh, Mohammadhasan Gholampour, Pooneh Memar Ardestani & Hamid Nemati. (2022) Application of cinnarizine in migraine prevention: A systematic review and meta‐analysis. Pain Practice 22:8, pages 733-745.
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Zachary A. Sorrentino, Dimitri Laurent, Jairo Hernandez, Caroline Davidson, Coulter Small, William Dodd & Brandon Lucke‐Wold. (2022) Headache persisting after aneurysmal subarachnoid hemorrhage: A narrative review of pathophysiology and therapeutic strategies. Headache: The Journal of Head and Face Pain 62:9, pages 1120-1132.
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Justine Perino, Virginie Corand, Elise Laurent, Hélène Théophile, Ghada Miremont‐Salamé, Antoine Pariente, Jean‐Laurent Colas, Thierry Couffinhal & Francesco Salvo. (2022) Myocardial infarction associated with erenumab: A case report. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 42:7, pages 585-589.
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Tom Skaria & Johannes Vogel. (2022) The Neuropeptide α-Calcitonin Gene-Related Peptide as the Mediator of Beneficial Effects of Exercise in the Cardiovascular System. Frontiers in Physiology 13.
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Louis K. Balcziak & Andrew F. Russo. (2022) Dural Immune Cells, CGRP, and Migraine. Frontiers in Neurology 13.
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Joshua Crawford, Sufang Liu & Feng Tao. (2022) Gut microbiota and migraine. Neurobiology of Pain 11, pages 100090.
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Eduardo Rivera-Mancilla & Antoinette MaassenVanDenBrink. 2022. Novel Synthetic Drugs in Migraine. Novel Synthetic Drugs in Migraine 1 17 .
E. V. Ekusheva, A. R. Artemenko, E. V. Shirshova, P. E. Sokov & A. M. Plieva. (2021) The use of the monoclonal antibody Erenumab in patients with chronic migraine in real clinical experience. Russian neurological journal 26:5, pages 44-50.
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Parisa Gazerani. (2021) A link between migraine and prolactin: the way forward. Future Science OA 7:9.
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Vicente González-Quintanilla, Sara Pérez-Pereda, Andrea González-Suárez, Jorge Madera, María Toriello & Julio Pascual. (2021) Restless legs-like syndrome as an emergent adverse event of CGRP monoclonal antibodies: A report of two cases. Cephalalgia 41:11-12, pages 1272-1275.
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Vladimír Kojecký. (2021) CGRP inhibitors and gastrointestinal tract. Neurologie pro praxi 22:4, pages 315-319.
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Eduardo Rivera-Mancilla, Linda Al-Hassany, Carlos M. Villalón & Antoinette MaassenVanDenBrink. (2021) Metabolic Aspects of Migraine: Association With Obesity and Diabetes Mellitus. Frontiers in Neurology 12.
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Linda Al-Hassany & Antoinette MaassenVanDenBrink. (2021) Drug interactions and risks associated with the use of triptans, ditans and monoclonal antibodies in migraine. Current Opinion in Neurology 34:3, pages 330-338.
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Simone de Vries Lentsch, Eloísa Rubio-Beltrán & Antoinette MaassenVanDenBrink. (2021) Changing levels of sex hormones and calcitonin gene-related peptide (CGRP) during a woman’s life: Implications for the efficacy and safety of novel antimigraine medications. Maturitas 145, pages 73-77.
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