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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 18, 2003 - Issue 5
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Research Article

Some 1,2-Diphenylethane Derivatives as Inhibitors of Retinoic Acid—Metabolising Enzymes

V.P. Greer Welsh School of Pharmacy, Cardiff University, Cathays Park, CFXF, 10 3, Cardiff, UK
,
P. Mason Welsh School of Pharmacy, Cardiff University, Cathays Park, CFXF, 10 3, Cardiff, UK
,
A.J. Kirby Welsh School of Pharmacy, Cardiff University, Cathays Park, CFXF, 10 3, Cardiff, UK
,
H.J. Smith Welsh School of Pharmacy, Cardiff University, Cathays Park, CFXF, 10 3, Cardiff, UKCorrespondence[email protected]
,
P.J. Nicholls Welsh School of Pharmacy, Cardiff University, Cathays Park, CFXF, 10 3, Cardiff, UK
&
C. Simons Welsh School of Pharmacy, Cardiff University, Cathays Park, CFXF, 10 3, Cardiff, UK
Pages 431-443 | Received 25 Nov 2002, Published online: 03 Oct 2008

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Peter Mason, Valerie P. Greer, Andrew J. Kirby, Claire Simons, Paul J. Nicholls & H. John Smith. (2003) Some Aryl Substituted 2-(4-Nitrophenyl)-4-oxo-4-phenylbutanoates and 3-(4-Nitrophenyl)-1-phenyl-1,4-butanediols and Related Compounds as Inhibitors of Rat Liver Microsomal Retinoic Acid Metabolising Enzymes. Journal of Enzyme Inhibition and Medicinal Chemistry 18:6, pages 511-528.
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Articles from other publishers (7)

Sambasivarao Kotha, Arjun S. Chavan & Deepti Goyal. (2015) Diversity-Oriented Approaches to Polycyclics and Bioinspired Molecules via the Diels–Alder Strategy: Green Chemistry, Synthetic Economy, and Beyond. ACS Combinatorial Science 17:5, pages 253-302.
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I. Volovych, M. Schwarze, Z. Nairoukh, J. Blum, M. Fanun & R. Schomäcker. (2014) Sol-gel immobilized catalyst systems for tandem transformations with trans-stilbene as an intermediate. Catalysis Communications 53, pages 1-4.
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Fengrong Li, Dongmei Zhao, Jinhong Ren, Feiyue Hao, Guyue Liu, Shengfei Jin, Yongkui Jing & Maosheng Cheng. (2013) 2-(2-Methylfuran-3-carboxamido)-3-phenylpropanoic acid, a potential CYP26A1 inhibitor to enhance all-trans retinoic acid-induced leukemia cell differentiation based on virtual screening and biological evaluation. Bioorganic & Medicinal Chemistry 21:11, pages 3256-3261.
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Sambasivarao Kotha & Priti Khedkar. (2009) A Diversity‐Oriented Approach to Diphenylalkanes by Strategic Utilization of [2+2+2] Cyclotrimerization, Cross‐Enyne Metathesis and Diels–Alder Reaction. European Journal of Organic Chemistry 2009:5, pages 730-738.
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Vincent C.O. Njar, Lalji Gediya, Puranik Purushottamachar, Pankaj Chopra, Tadas Sean Vasaitis, Aakanksha Khandelwal, Jhalak Mehta, Carlic Huynh, Aashvini Belosay & Jyoti Patel. (2006) Retinoic acid metabolism blocking agents (RAMBAs) for treatment of cancer and dermatological diseases. Bioorganic & Medicinal Chemistry 14:13, pages 4323-4340.
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Sook Wah YeeLaetitia JarnoMohamed Sayed GomaaCarole ElfordLi-Ling OoiMichael P. CooganRichard McClellandRobert Ian NicholsonBronwen A. J. EvansAndrea BrancaleClaire Simons. (2005) Novel Tetralone-Derived Retinoic Acid Metabolism Blocking Agents:  Synthesis and in Vitro Evaluation with Liver Microsomal and MCF-7 CYP26A1 Cell Assays. Journal of Medicinal Chemistry 48:23, pages 7123-7131.
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Jyoti B. PatelCarlic K. HuynhVenkatesh D. HandrattaLalji K. GediyaAngela M. H. BrodieOlga G. GoloubevaOmoshile O. ClementIvo P. NanneDianne Robert SopranoVincent C. O. Njar. (2004) Novel Retinoic Acid Metabolism Blocking Agents Endowed with Multiple Biological Activities Are Efficient Growth Inhibitors of Human Breast and Prostate Cancer Cells in Vitro and a Human Breast Tumor Xenograft in Nude Mice. Journal of Medicinal Chemistry 47:27, pages 6716-6729.
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