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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 20, 2005 - Issue 4
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Research Article

The influence of product instability on slow-binding inhibition

C. Garrido-del Solo Escuela Politécnica Superior, Universidad de Castilla-La Mancha.Avda, Departamento de Química-Física, España, s/n. Campus Universitario, E-02071, Albacete, Spain
,
J. M. Yago Escuela Politécnica Superior, Universidad de Castilla-La Mancha.Avda, Departamento de Química-Física, España, s/n. Campus Universitario, E-02071, Albacete, Spain
,
M. García-Moreno Escuela Politécnica Superior, Universidad de Castilla-La Mancha.Avda, Departamento de Química-Física, España, s/n. Campus Universitario, E-02071, Albacete, Spain
,
B. H. Havsteen Christian-Albrechts-Universität zu Kiel, Biochemisches Institut der Medizinischen Fakultät, Olshausenstr., 40., 24098, Kiel, Germany
,
F. García-Cánovas Universidad de Murcia, Departamento de Bioquímica y Biología Molecular A, Facultad de Veterinaria, Spain
&
R. Varón Escuela Politécnica Superior, Universidad de Castilla-La Mancha.Avda, Departamento de Química-Física, España, s/n. Campus Universitario, E-02071, Albacete, Spain
Pages 309-316 | Received 05 Nov 2004, Accepted 31 Jan 2005, Published online: 04 Oct 2008

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Rumin Zhang & Kenny Wong. (2017) High performance enzyme kinetics of turnover, activation and inhibition for translational drug discovery. Expert Opinion on Drug Discovery 12:1, pages 17-37.
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Articles from other publishers (2)

E. Arribas, J. M. Villalba, M. Garcia-Moreno, M. L. Amo, F. Garcia-Sevilla, F. Garcia-Molina, J. L. Muñoz-Muñoz & R. Varon. (2011) Characterization of unstable enzyme systems which evolve according to a three-exponential equation. Journal of Mathematical Chemistry 49:8, pages 1667-1686.
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E. Arribas, H. Bisswanger, A. Sotos-Lomas, M. Garcia-Moreno, F. Garcia-Canovas, J. Donoso-Pardo, F. Muñoz-Izquierdo & R. Varon. (2007) A method, based on statistical moments, to evaluate the kinetic parameters involved in unstable enzyme systems. Journal of Mathematical Chemistry 44:2, pages 379-404.
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