1,232
Views
32
CrossRef citations to date
0
Altmetric
Research Article

Efavirenz Mannich bases: Synthesis, anti-HIV and antitubercular activities

, &
Pages 1-5 | Received 05 Oct 2006, Accepted 02 Mar 2007, Published online: 01 Feb 2009

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

E. M. Abdel Bary, Ammar N. Harmal & Moustafa A. Gouda. (2019) Synthesis, characterization, swelling-deswelling properties of Novel nanoparticle-hydrogel containing core chitosan and their cyclohexanone-crosslinked counterparts. Polymer-Plastics Technology and Materials 58:9, pages 992-1004.
Read now
Nisheeth C. Desai, Nayan B. Bhatt & Surbhi B. Joshi. (2019) Synthetic modifications in ethyl 2-amino-4-methylthiazole-5-carboxylate: 3D QSAR analysis and antimicrobial study. Synthetic Communications 49:8, pages 1055-1066.
Read now
Jason A Wiles, Barton J Bradbury & Michael J Pucci. (2010) New quinolone antibiotics: a survey of the literature from 2005 to 2010. Expert Opinion on Therapeutic Patents 20:10, pages 1295-1319.
Read now

Articles from other publishers (29)

Van‐Son Nguyen, Vo Thanh Cong & Tran Nguyen Minh An. (2023) A Review of the Synthesis and Biological Activity of Flavonoid Mannich Base Derivatives. ChemistrySelect 8:46.
Crossref
Debora Inacio Leite, Stefany de Castro Bazan Moura, Maria da Conceição Avelino Dias, Carolina Catta Preta Costa, Gustavo Peixoto Machado, Luiz Claudio Ferreira Pimentel, Frederico Silva Castelo Branco, Rui Moreira, Monica Macedo Bastos & Nubia Boechat. (2023) A Review of the Development of Multitarget Molecules against HIV-TB Coinfection Pathogens. Molecules 28:8, pages 3342.
Crossref
Hayat Ullah, Muhammad Waseem Aslam, Fazal Rahim, Amjad Hussain & Muhammad Perviaz. (2023) Synthesis, in vitro α-glucosidase and α-amylase activities and molecular docking study of oxadiazole-sulphonamide hybrid analogues. Chemical Data Collections, pages 101031.
Crossref
László Lázár & Ferenc Fülöp. 2022. Comprehensive Heterocyclic Chemistry IV. Comprehensive Heterocyclic Chemistry IV 416 479 .
Palani Natarajan, Deachen Chuskit, Priya & Manjeet. (2022) Transition-metal-free synthesis of trifluoromethylated benzoxazines via a visible-light-promoted tandem difunctionalization of o -vinylanilides with trifluoromethylsulfinate . New Journal of Chemistry 46:1, pages 322-327.
Crossref
Somali Mukherjee, Sili Hansda, Sudeshna Nandi, Tonmoy Chakraborty, Debabrata Samanta, Krishnendu Acharya & Debasis Das. (2021) Azide-mediated unusual in situ transformation of Mannich base to Schiff–Mannich base and isolation of their Cu( ii ) complexes: crystal structure, theoretical inspection and anticancer activities . Dalton Transactions 50:38, pages 13374-13386.
Crossref
Zeid Hassan Abood, Husham Attallah Suhail & Zahraa Kadum Chafcheer. (2021) Synthesis of 1,3-Benzoxazepine-1,5-diones containing Oxadiazole unit with Assessment of their verves Athwart Bacteria. Research Journal of Pharmacy and Technology, pages 1837-1841.
Crossref
Venakata Naresh Vema, Bharathi Kumari Y, Venkata Basaveswara Rao Mandava, Sridhar Mussulla, Ramakrishnam Raju Addada & Srinivasa Rao A. (2020) Synthesis, anticancer evaluation and molecular docking studies of 1,3,4-oxadiazole linked resveratrol derivatives. Chemical Data Collections 30, pages 100570.
Crossref
Sampath Bitla, Someswar Rao Sagurthi, Ramulu Dhanavath, Muralidhar Reddy Puchakayala, Saritha Birudaraju, Akkiraju Anjini Gayatri, Vijaya Kumar Bhukya & Krisham Raju Atcha. (2020) Design and synthesis of triazole conjugated novel 2,5-diaryl substituted 1,3,4-oxadiazoles as potential antimicrobial and anti-fungal agents. Journal of Molecular Structure 1220, pages 128705.
Crossref
K. Kucukoglu, H. I. Gul & H. Sakagami. (2020) Evaluation of Cytotoxic Properties of N,N'-bis[(1-aryl-3-heteroaryl)propylidene]-hydrazine dihydrochlorides. Pharmaceutical Chemistry Journal 54:8, pages 784-787.
Crossref
Deepak M. Nagrik & Umesh S. Shelke. (2020) Synthesis of N-Mannich bases from 3, 4-dihydropyrimidin-2(1H)-ones by using nanostructured Cobalt Chloride Doped Polyaniline Composite as Catalyst (PANI-Co). Journal of Physics: Conference Series 1644:1, pages 012018.
Crossref
Vema Venkata Naresh, Y. Bharathi Kumari, Mussulla Sridhar, Addada Ramakrishnam Raju & A. Srinivasa Rao. (2020) Synthesis and Biological Evaluation of 1,3,4-Oxadiazole Fused Resveratrol Derivatives as Anticancer Agents. Asian Journal of Chemistry 32:8, pages 1967-1971.
Crossref
Avinash Kumar, Rajappan Revathi, Dharmarajan Sriram, Francesca Curreli, Asim K. Debnath, K. Sreedhara Pai & Suvarna G. Kini. (2019) Targeting HIV‐TB coinfection by developing novel piperidin‐4‐substituted imines: Design, synthesis, in vitro and in silico studies. Archiv der Pharmazie 352:6, pages 1800358.
Crossref
Zanjam Spandana, Reddymasu Sreenivasulu, Tadigiri MalathiRekha & Mandava Venkata Basaveswara Rao. (2019) Novel 1,3,4-Oxadiazole Fused Thiadiazole Derivatives: Synthesis and study of Anticancer Activities. Letters in Drug Design & Discovery 16:6, pages 656-662.
Crossref
Atukuri  Dorababu, Ravindra R. Kamble, Atulkumar A. Kamble, Mahadev N. Kumbar, SabaKauser J. Shaikh & Sandeep P. Netalkar. (2019) Mannich Bases of 1,2,4-Triazolones as Potent Anti-Tubercular and Antifungal Agents. ChemistrySelect 4:10, pages 2881-2885.
Crossref
Elena V. Tret’yakova, Gul’sasyak F. Zakirova, Elena V. Salimova, Olga S. Kukovinets, Victor N. Odinokov & Lyudmila V. Parfenova. (2018) Convenient one-pot synthesis of resin acid Mannich bases as novel anticancer and antifungal agents. Medicinal Chemistry Research 27:9, pages 2199-2213.
Crossref
Rubén Martín-Escolano, Elsa Moreno-Viguri, Mery Santivañez-Veliz, Alvaro Martin-Montes, Encarnación Medina-Carmona, Rocío Paucar, Clotilde Marín, Amaya Azqueta, Nuria Cirauqui, Angel L. Pey, Silvia Pérez-Silanes & Manuel Sánchez-Moreno. (2018) Second Generation of Mannich Base-Type Derivatives with in Vivo Activity against Trypanosoma cruzi . Journal of Medicinal Chemistry 61:13, pages 5643-5663.
Crossref
Łukasz Popiołek, Anna Biernasiuk, Kinga Paruch, Anna Malm & Monika Wujec. (2018) Synthesis and in vitro antimicrobial activity screening of new pipemidic acid derivatives. Archives of Pharmacal Research 41:6, pages 633-645.
Crossref
D. D. Orlova, D. S. Novikova, A. V. Garabadzhiu & V. G. Tribulovich. (2018) A Study on Hydrolytic Stability of Isatin N-Mannich Bases. Russian Journal of General Chemistry 88:1, pages 48-56.
Crossref
Abdullah Alaklab, Radhakrishnan Surendra Kumar, Anis Ahamed, Ibrahim A. Arif, Aseer Manilal & Akbar Idhayadhulla. (2016) Synthesis of novel three compound imidazole derivatives via Cu(II) catalysis and their larvicidal and antimicrobial activities. Monatshefte für Chemie - Chemical Monthly 148:2, pages 275-290.
Crossref
Nadiah Ameram & Farook Adam. (2015) Iron Carbonyl Thiourea Hybrid Material Based on Functionalised Silica from Rice Husk Ash for Oxidation of Limonene. Procedia Chemistry 16, pages 700-708.
Crossref
Gheorghe Roman. (2015) Mannich bases in medicinal chemistry and drug design. European Journal of Medicinal Chemistry 89, pages 743-816.
Crossref
Shridhar Malladi, Arun M. Isloor, S.K. Peethambar & Hoong Kun Fun. (2014) Synthesis and biological evaluation of newer analogues of 2,5-disubstituted 1,3,4-oxadiazole containing pyrazole moiety as antimicrobial agents. Arabian Journal of Chemistry 7:6, pages 1185-1191.
Crossref
A. N. Antimonova, N. I. Petrenko, M. M. Shakirov, M. A. Pokrovskii, A. G. Pokrovskii & E. E. Shul’ts. (2014) Synthesis and Cytotoxic Activity of Lupane Triterpenoids Containing 1,3,4-Oxadiazoles. Chemistry of Natural Compounds.
Crossref
Suman Bala, Neha Sharma, Anu Kajal, Sunil Kamboj & Vipin Saini. (2014) Mannich Bases: An Important Pharmacophore in Present Scenario. International Journal of Medicinal Chemistry 2014, pages 1-15.
Crossref
N.C. Desai, Amit M. Dodiya, Kiran M. Rajpara & Yogesh M. Rupala. (2014) Synthesis and antimicrobial screening of 1,3,4-oxadiazole and clubbed thiophene derivatives. Journal of Saudi Chemical Society 18:3, pages 255-261.
Crossref
Shahrukh T. Asundaria, Christophe Pannecouque, Erik De Clercq, Claudiu T. Supuran & Keshav C. Patel. (2013) Synthesis of novel biologically active methylene derivatives of sydnones. Medicinal Chemistry Research 22:12, pages 5752-5763.
Crossref
M. M. Kamel, M. M. Anwar, A. M. Soliman & H. F. Abdel-Hamid. (2012) In vitro antischistosomal evaluation of some newly synthesized praziquantel derivatives. Research on Chemical Intermediates 39:7, pages 3417-3426.
Crossref
Wael M. El‐Sayed, Tarek Aboul‐Fadl & Michael R. Franklin. (2010) Effects of isatin‐isoniazid derivatives on drug metabolizing and chemoprotective enzymes in mice. Drug Development Research 71:5, pages 313-322.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.