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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 24, 2009 - Issue 1
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Research Article

QSAR study of substituted 2-pyridinyl guanidines as selective urokinase-type plasminogen activator (uPA) inhibitors

C. Karthikeyan School of Pharmaceutical Sciences, Rajiv Gandhi Technical University, Airport Bypass Road, Gandhi Nagar, Bhopal 462036, MP, India
,
N.S. Hari Narayana Moorthy School of Pharmaceutical Sciences, Rajiv Gandhi Technical University, Airport Bypass Road, Gandhi Nagar, Bhopal 462036, MP, India
&
Piyush Trivedi School of Pharmaceutical Sciences, Rajiv Gandhi Technical University, Airport Bypass Road, Gandhi Nagar, Bhopal 462036, MP, India
Pages 6-13 | Received 09 Jun 2007, Accepted 19 Oct 2007, Published online: 01 Feb 2009

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V.V. Kleandrova, M.T. Scotti, L. Scotti, A. Nayarisseri & A. Speck-Planche. (2020) Cell-based multi-target QSAR model for design of virtual versatile inhibitors of liver cancer cell lines. SAR and QSAR in Environmental Research 31:11, pages 815-836.
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N.S. Hari Narayana Moorthy, Maria J. Ramos & Pedro A. Fernandes. (2011) Topological, hydrophobicity, and other descriptors on α-glucosidase inhibition: a QSAR study on xanthone derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 26:6, pages 755-766.
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NS Hari Narayana Moorthy, Maria J Ramos & Pedro A Fernandes. (2011) Prediction of the relationship between the structural features of andrographolide derivatives and α-glucosidase inhibitory activity: A quantitative structure-activity relationship (QSAR) Study. Journal of Enzyme Inhibition and Medicinal Chemistry 26:1, pages 78-87.
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Articles from other publishers (10)

Nehad S El Salamouni, Benjamin J. Buckley, Marie Ranson, Michael J. Kelso & Haibo Yu. (2022) Urokinase plasminogen activator as an anti-metastasis target: inhibitor design principles, recent amiloride derivatives, and issues with human/mouse species selectivity. Biophysical Reviews 14:1, pages 277-301.
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Alejandro Speck-Planche, Valeria V. Kleandrova & Marcus T. Scotti. (2021) In Silico Drug Repurposing for Anti-Inflammatory Therapy: Virtual Search for Dual Inhibitors of Caspase-1 and TNF-Alpha. Biomolecules 11:12, pages 1832.
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Yusuf Isyaku, Adamu Uzairu & Sani Uba. (2020) In silico studies of novel pyrazole-furan and pyrazole-pyrrole carboxamide as fungicides against Sclerotinia sclerotiorum. Beni-Suef University Journal of Basic and Applied Sciences 9:1.
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Yusuf Isyaku, Adamu Uzairu & Sani Uba. (2020) QSAR and molecular docking studies of novel 2,5-distributed-1,3,4-thiadiazole derivatives containing 5-phenyl-2-furan as fungicides against Phythophthora infestans. Beni-Suef University Journal of Basic and Applied Sciences 9:1.
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Yusuf Isyaku, Adamu Uzairu, Sani Uba, Muhammad Tukur Ibrahim & Abdullahi Bello Umar. (2020) QSAR, molecular docking, and design of novel 4-(N,N-diarylmethyl amines) Furan-2(5H)-one derivatives as insecticides against Aphis craccivora. Bulletin of the National Research Centre 44:1.
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Ghasem Ghasemi, Sattar Arshadi, Alireza Nemati Rashtehroodi, Mahyar Nirouei, Shahab Shariati & Zinab Rastgoo. (2013) QSAR Investigation on Quinolizidinyl Derivatives in Alzheimer’s Disease. Journal of Computational Medicine 2013, pages 1-8.
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Ashutosh Kumar Pandey, Omprakash Tanwar, Girdhar Singh Deora, Chandrabose Karthikeyan, N. S. Hari Narayana Moorthy & Piyush Trivedi. (2011) Modeling VEGFR kinase inhibition of aminopyrazolopyridine urea derivatives using topological and physicochemical descriptors: a quantitative structure activity analysis study. Medicinal Chemistry Research 21:12, pages 3958-3964.
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N. S. Hari Narayana Moorthy, Nuno S. Cerqueira, Maria J. Ramos & Pedro A. Fernandes. (2010) QSAR analysis of 2-benzoxazolyl hydrazone derivatives for anticancer activity and its possible target prediction. Medicinal Chemistry Research 21:2, pages 133-144.
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N.S. Hari Narayana Moorthy, Maria J. Ramos & Pedro A. Fernandes. (2011) Structural analysis of α-glucosidase inhibitors by validated QSAR models using topological and hydrophobicity based descriptors. Chemometrics and Intelligent Laboratory Systems 109:2, pages 101-112.
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N.S. Hari Narayana Moorthy, Sergio F. Sousa, Maria J. Ramos & Pedro A. Fernandes. (2011) In Silico–Based Structural Analysis of Arylthiophene Derivatives for FTase Inhibitory Activity, hERG, and Other Toxic Effects. SLAS Discovery 16:9, pages 1037-1046.
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