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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 24, 2009 - Issue 1
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Research Article

Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Campylobacter jejuni

Juan A. Musso-Buendía Instituto de Parastiología y Biomedicina “López-Neyra”. Consejo Superior de Investigaciones Científicas, Avda. del Conocimiento s/n. Parque Tecnológico Ciencias de la Salud, 18100, Armilla, Granada, Spain
,
Antonio E. Vidal Instituto de Parastiología y Biomedicina “López-Neyra”. Consejo Superior de Investigaciones Científicas, Avda. del Conocimiento s/n. Parque Tecnológico Ciencias de la Salud, 18100, Armilla, Granada, Spain
,
Ganasan Kasinthan Welsh School of Pharmacy, Cardiff University, Po Box 1086, Redwood Building, King Edward VII Avenue, Cardiff, UK
,
Corinne Nguyen Welsh School of Pharmacy, Cardiff University, Po Box 1086, Redwood Building, King Edward VII Avenue, Cardiff, UK
,
Juana Carrero-Lérida Instituto de Parastiología y Biomedicina “López-Neyra”. Consejo Superior de Investigaciones Científicas, Avda. del Conocimiento s/n. Parque Tecnológico Ciencias de la Salud, 18100, Armilla, Granada, Spain
,
Luis M. Ruiz-pérez Instituto de Parastiología y Biomedicina “López-Neyra”. Consejo Superior de Investigaciones Científicas, Avda. del Conocimiento s/n. Parque Tecnológico Ciencias de la Salud, 18100, Armilla, Granada, Spain
,
Keith Wilson Department of Chemistry, Structural Biology Laboratory, University of York, Heslington, York, UK
,
Nils Gunnar Johansson Medivir AB, SE-14122, Huddinge, Sweden
,
Ian H. Gilbert Welsh School of Pharmacy, Cardiff University, Po Box 1086, Redwood Building, King Edward VII Avenue, Cardiff, UK
&
Dolores González-Pacanowska Instituto de Parastiología y Biomedicina “López-Neyra”. Consejo Superior de Investigaciones Científicas, Avda. del Conocimiento s/n. Parque Tecnológico Ciencias de la Salud, 18100, Armilla, Granada, SpainCorrespondence[email protected]
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Pages 111-116 | Received 17 Oct 2007, Accepted 03 Dec 2007, Published online: 20 Oct 2008

Citations (6)

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Rinki Sisodia, Debapriyo Sarmadhikari, Pooja Anjali Mazumdar, Shailendra Asthana & Chaithanya Madhurantakam. (2023) Molecular analysis of dUTPase of Helicobacter pylori for identification of novel inhibitors using in silico studies. Journal of Biomolecular Structure and Dynamics 0:0, pages 1-26.
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Articles from other publishers (5)

Nabeel Backer, Adarsh Kumar, Ankit Kumar Singh, Harshwardhan Singh, Balasubramanian Narasimhan & Pradeep Kumar. (2023) Medicinal chemistry aspects of uracil containing dUTPase inhibitors targeting colorectal cancer. Drug Discovery Today, pages 103853.
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Jorge Donderis, Janine Bowring, Elisa Maiques, J. Rafael Ciges-Tomas, Christian Alite, Iltyar Mehmedov, María Angeles Tormo-Mas, José R. Penadés & Alberto Marina. (2017) Convergent evolution involving dimeric and trimeric dUTPases in pathogenicity island mobilization. PLOS Pathogens 13:9, pages e1006581.
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Kinga Nyíri & Beáta G. Vértessy. (2017) Perturbation of genome integrity to fight pathogenic microorganisms. Biochimica et Biophysica Acta (BBA) - General Subjects 1861:1, pages 3593-3612.
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Ana Maria D. Gonçalves, Daniele de Sanctis & Sean M. McSweeney. (2011) Structural and Functional Insights into DR2231 Protein, the MazG-like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus radiodurans. Journal of Biological Chemistry 286:35, pages 30691-30705.
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Ildikó PécsiJudit E. SzabóScott D. AdamsIstván SimonJames R. Sellers, Beáta G. Vértessy & Judit Tóth. (2011) Nucleotide pyrophosphatase employs a P-loop-like motif to enhance catalytic power and NDP/NTP discrimination. Proceedings of the National Academy of Sciences 108:35, pages 14437-14442.
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