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Research Article

Antidiabetic Effect of an Active Fraction Extracted from Dragon's Blood (Dracaena Cochinchinensis)

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Pages 136-139 | Received 10 Oct 2007, Accepted 07 Nov 2007, Published online: 20 Oct 2008

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Iman E. Helal, Marwa Elsbaey, Ahmed M. Zaghloul & El-Sayed S. Mansour. (2021) A unique C-linked chalcone-dihydrochalcone dimer from Dracaena cinnabari resin. Natural Product Research 35:15, pages 2558-2563.
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Jiumn-Yih Wu, Hsiou-Yu Ding, Tzi-Yuan Wang, Cheng-Zhi Cai & Te-Sheng Chang. (2023) Antioxidant and anti-α-glucosidase activities of biotransformable dragon’s blood via predicted data mining approach. Process Biochemistry 130, pages 166-173.
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Jiling Yi, Ting Zhao, Yuanlin Zhang, Yanxing Tan, Xiao Han, Yulin Tang & Guangying Chen. (2022) Isolated compounds from Dracaena angustifolia Roxb and acarbose synergistically/additively inhibit α-glucosidase and α-amylase: an in vitro study. BMC Complementary Medicine and Therapies 22:1.
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Jiangbin Liang, Song Mei, Xiangyu Qiao, Wei Pan, Yan Zhao, Shaohui Shi, Yaling Zhai, Haizhao Wen, Guoping Wu & Chengyu Jiang. (2021) A botanical medicine dragon’s blood exhibited clinical antithrombosis efficacy similar to low molecular weight heparin. Science China Life Sciences 64:10, pages 1691-1701.
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Yujuan Li, Shan Liu, Huayan Liu, Yaoyuan Cui & Yulin Deng. (2021) Dragon’s Blood Regulates Rac1-WAVE2-Arp2/3 Signaling Pathway to Protect Rat Intestinal Epithelial Barrier Dysfunction Induced by Simulated Microgravity. International Journal of Molecular Sciences 22:5, pages 2722.
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Yang Liu, Xiangsheng Zhao, Ruyu Yao, Chuangjun Li, Zhonglian Zhang, Yanhong Xu & Jian-He Wei. (2021) Dragon’s Blood from Dracaena Worldwide: Species, Traditional Uses, Phytochemistry and Pharmacology . The American Journal of Chinese Medicine 49:06, pages 1315-1367.
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Guang-Zhen Lang, Chuang-Jun Li, Tong-Yue Gaohu, Chuan Li, Jie Ma, Jing-Zhi Yang, Tian-Tian Zhou, Yu-He Yuan, Fei Ye, Jian-He Wei & Dong-Ming Zhang. (2020) Bioactive flavonoid dimers from Chinese dragon's blood, the red resin of Dracaena cochinchinensis. Bioorganic Chemistry 97, pages 103659.
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Jing Sun, Jia-Ni Liu, Bei Fan, Xiao-Nan Chen, Dao-Ran Pang, Jiao Zheng, Qian Zhang, Yun-Fang Zhao, Wei Xiao, Peng-Fei Tu, Yue-Lin Song & Jun Li. (2019) Phenolic constituents, pharmacological activities, quality control, and metabolism of Dracaena species: A review. Journal of Ethnopharmacology 244, pages 112138.
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Zakieh Keshavarzi, Farzaneh Shakeri, George E. Barreto, Bahram Bibak, Thozhukat Sathyapalan & Amirhossein Sahebkar. (2019) Medicinal plants in traumatic brain injury: Neuroprotective mechanisms revisited. BioFactors 45:4, pages 517-535.
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Dao-Ran Pang, Bo Pan, Jing Sun, Hui Sun, Hui-Na Yao, Yue-Lin Song, Yun-Fang Zhao, Peng-Fei Tu, Wen-Zhe Huang, Jiao Zheng & Jun Li. (2018) Homoisoflavonoid derivatives from the red resin of Dracaena cochinchinensis. Fitoterapia 131, pages 105-111.
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Muhammad Ajmal Shah, Ruqaiya Khalil, Zaheer Ul-Haq & Pharkphoom Panichayupakaranant. (2017) α-Glucosidase inhibitory effect of rhinacanthins-rich extract from Rhinacanthus nasutus leaf and synergistic effect in combination with acarbose. Journal of Functional Foods 36, pages 325-331.
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Yujuan Li, Yushi Zhang, Rui Wang, Lizhong Wei, Yulin Deng & Wei Ren. (2017) Metabolic profiling of five flavonoids from Dragon's Blood in human liver microsomes using high-performance liquid chromatography coupled with high resolution mass spectrometry. Journal of Chromatography B 1052, pages 91-102.
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Yuelin Zhang, Yijie Sha, Kai Qian, Xu Chen & Qin Chen. (2017) Comparison of three methods for analyzing loureirin B and human serum albumin interaction using capillary electrophoresis. ELECTROPHORESIS 38:7, pages 1038-1043.
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Yujuan Li, George Q. Li, Yongzhi Li, Yulin Deng & Li Deng. (2016) Development and application of an UHPLC–MS method for comparative pharmacokinetic study of phenolic components from dragon’s blood in rats under simulated microgravity environment. Journal of Pharmaceutical and Biomedical Analysis 121, pages 91-98.
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Lin Hu, Fang-Fang Wang, Xing-Hong Wang, Qing-Song Yang, Yong Xiong & Wen-Xing Liu. (2015) Phytoconstituents from the leaves of Dracaena cochinchinensis (Lour.) S. C. Chen. Biochemical Systematics and Ecology 63, pages 1-5.
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Xu Chen, Kai Qian & Qin Chen. (2015) Comparison between loureirin A and cochinchinenin C on the interaction with human serum albumin. European Journal of Medicinal Chemistry 93, pages 492-500.
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Xiao-Qin Su, Yue-Lin Song, Jing Zhang, Hui-Xia Huo, Zheng Huang, Jiao Zheng, Qian Zhang, Yun-Fang Zhao, Wei Xiao, Jun Li & Peng-Fei Tu. (2014) Dihydrochalcones and homoisoflavanes from the red resin of Dracaena cochinchinensis (Chinese dragon's blood). Fitoterapia 99, pages 64-71.
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Jia-Yi Fan, Tao Yi, Chui-Mei Sze-To, Lin Zhu, Wan-Ling Peng, Ya-Zhou Zhang, Zhong-Zhen Zhao & Hu-Biao Chen. (2014) A Systematic Review of the Botanical, Phytochemical and Pharmacological Profile of Dracaena cochinchinensis, a Plant Source of the Ethnomedicine “Dragon’s Blood”. Molecules 19:7, pages 10650-10669.
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Yi Chang, Ting-Chen Chang, Jie-Jen Lee, Nen-Chung Chang, Yung-Kai Huang, Cheuk-Sing Choy & Thanasekaran Jayakumar. (2014) Sanguis draconis , a Dragon’s Blood Resin, Attenuates High Glucose-Induced Oxidative Stress and Endothelial Dysfunction in Human Umbilical Vein Endothelial Cells . The Scientific World Journal 2014, pages 1-10.
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Haiyan Zhao & Zilin Chen. (2013) An HPLC-ESI-MS method for analysis of loureirin A and B in dragon's blood and application in pharmacokinetics and tissue distribution in rats. Fitoterapia 86, pages 149-158.
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Chien-Ming Hu, Joe-Sharg Li, Khoot-Peng Cheah, Che-Wei Lin, Wen-Yu Yu, Ming-Long Chang, Geng-Chang Yeh, Sheng-Hsuan Chen, Hui-Wen Cheng & Cheuk-Sing Choy. (2011) Effect of Sanguis draconis (a dragon's blood resin) on streptozotocin- and cytokine-induced β-cell damage, in vitro and in vivo. Diabetes Research and Clinical Practice 94:3, pages 417-425.
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Yushi Zhang, Yongzhi Li, Bo Chen, Yulin Deng & Yujuan Li. (2011) Simultaneous quantification of loureirin A and loureirin B in rat urine, feces, and bile by HPLC-MS/MS method and its application to excretion study. Analytical and Bioanalytical Chemistry 400:4, pages 1181-1187.
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