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Research Article

CoMFA and CoMSIA 3D-QSAR analysis on hydroxamic acid derivatives as urease inhibitors

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Pages 272-278 | Received 11 Oct 2007, Accepted 26 Feb 2008, Published online: 20 Oct 2008

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Richa Arora, Upasana Issar & Rita Kakkar. (2019) Identification of novel urease inhibitors: pharmacophore modeling, virtual screening and molecular docking studies. Journal of Biomolecular Structure and Dynamics 37:16, pages 4312-4326.
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Wen-Long Duan, Jie Li, Lian-Xin Xin, Yuan-Liang Shi & Fang Guo. (2020) Structures, kinetic and synergistic mechanisms studies of urease inhibition of copper(II) complex based on MOSs. Journal of Molecular Structure 1209, pages 127958.
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Zhonglu You, Huiyuan Yu, Boyang Zheng, Chenglu Zhang, Chengwei Lv, Kun Li & Lin Pan. (2018) Syntheses, structures, and inhibition studies of Jack bean urease by copper(II) complexes derived from a tridentate hydrazone ligand. Inorganica Chimica Acta 469, pages 44-50.
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Zhonglu You, Mingyang Liu, Cunfang Wang, Guihua Sheng, Xinlu Zhao, Dan Qu & Fang Niu. (2016) Inhibition studies of Helicobacter pylori urease with Schiff base copper( ii ) complexes . RSC Advances 6:20, pages 16679-16690.
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Satya P. Gupta. (2015) QSAR Studies on Hydroxamic Acids: A Fascinating Family of Chemicals with a Wide Spectrum of Activities. Chemical Reviews 115:13, pages 6427-6490.
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Harun M. Patel, Malleshappa N. Noolvi, Poonam Sharma, Varun Jaiswal, Sumit Bansal, Sandeep Lohan, Suthar Sharad Kumar, Vikrant Abbot, Saurabh Dhiman & Varun Bhardwaj. (2014) Quantitative structure–activity relationship (QSAR) studies as strategic approach in drug discovery. Medicinal Chemistry Research 23:12, pages 4991-5007.
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G. H. Sheng, Y. Huo, Y. T. Ye, Z. You & H. L. Zhu. (2014) Urease inhibition of oxovanadium(V) complexes with hydrazone and hydroxamate ligands. Russian Journal of Coordination Chemistry 40:9, pages 664-670.
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Reaz Uddin, Maria Saeed & Zaheer Ul-Haq. (2013) Molecular docking- and genetic algorithm-based approaches to produce robust 3D-QSAR models. Medicinal Chemistry Research 23:5, pages 2198-2206.
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Umer Rashid, Iram Batool, Abdul Wadood, Ajmal Khan, Zaheer ul-Haq, Muhammad Iqbal Chaudhary & Farzana Latif Ansari. (2013) Structure based virtual screening-driven identification of monastrol as a potent urease inhibitor. Journal of Molecular Graphics and Modelling 43, pages 47-57.
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E. M. F. Muri & T. G. Barros. 2013. Hydroxamic Acids. Hydroxamic Acids 241 253 .
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Zaheer Ul-Haq, Uzma Mahmood, Sualeha Reza, Reaz Uddin & Mehwish Aleem. (2011) Ligand-Based 3D-QSAR Studies of Diaryl Acyl-sulfonamide Analogues as Human Umbilical Vein Endothelial Cells Inhibitors Stimulated by VEGF. Chemical Biology & Drug Design 77:4, pages 288-294.
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Zaheer Ul-Haq, Uzma Mahmood & Bushra Jehangir. (2009) Ligand-based 3D-QSAR Studies of Physostigmine Analogues as Acetylcholinesterase Inhibitors. Chemical Biology & Drug Design 74:6, pages 571-581.
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