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Journal of Enzyme Inhibition and Medicinal Chemistry Volume 24, 2009 - Issue 3
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Research Article

2,4,5-trimethoxycinnamic acid: the major metabolite of α-asarone, retains most of the pharmacological properties of α-asarone

Javier Antunez-SolisDepartamento de Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Apartado Postal 4-129, Admon. 4, México City 06401, Mexico
,
Fernando Hernández-DerramaderoDepartamento de Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Apartado Postal 4-129, Admon. 4, México City 06401, Mexico
,
Mayda Aquino-VegaDepartamento de Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Apartado Postal 4-129, Admon. 4, México City 06401, Mexico
,
Selene Ibarra-RamírezDepartamento de Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Apartado Postal 4-129, Admon. 4, México City 06401, Mexico
,
Lorena Rodríguez-PáezDepartamento de Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Apartado Postal 4-129, Admon. 4, México City 06401, Mexico
,
Isabel BaezaDepartamento de Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Apartado Postal 4-129, Admon. 4, México City 06401, Mexico
&
Carlos WongDepartamento de Bioquímica, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Apartado Postal 4-129, Admon. 4, México City 06401, MexicoCorrespondence[email protected]
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Pages 903-909 | Received 30 Jan 2008, Accepted 22 May 2008, Published online: 20 Oct 2008

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Michael N. Clifford, Laurence J. King, Asimina Kerimi, Maria Gema Pereira-Caro & Gary Williamson. (2022) Metabolism of phenolics in coffee and plant-based foods by canonical pathways: an assessment of the role of fatty acid β-oxidation to generate biologically-active and -inactive intermediates. Critical Reviews in Food Science and Nutrition 0:0, pages 1-58.
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Hua Lu, Jianbo Li, Man Li, Tao Gong & Zhirong Zhang. (2015) Systemic delivery of alpha-asarone with Kolliphor HS 15 improves its safety and therapeutic effect on asthma. Drug Delivery 22:3, pages 266-275.
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Articles from other publishers (10)

MD Maseehullah, Mohammad Zakir, Mohd Anas & Munawwar Husain Kazmi. (2022) Ethno-pharmacology of Asaroon ( Asarum europaeum L.) with special reference to Unani System of Medicine . Journal of Complementary and Integrative Medicine 19:2, pages 181-192.
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Mingcui Zheng, Zhenhong Liu, Lulu Mana, Gaofeng Qin, Shuaiyang Huang, Zhuoyan Gong, Meijing Tian, Yannan He & Pengwen Wang. (2021) Shenzhiling oral liquid protects the myelin sheath against Alzheimer's disease through the PI3K/Akt-mTOR pathway. Journal of Ethnopharmacology 278, pages 114264.
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Magdalena D. Pieczynska, Yang Yang, S. Petrykowski, Olaf K. Horbanczuk, Atanas G. Atanasov & Jaroslaw O. Horbanczuk. (2020) Gut Microbiota and Its Metabolites in Atherosclerosis Development. Molecules 25:3, pages 594.
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Dongdong Wang, Yang Yang, Yingnan Lei, Nikolay T. Tzvetkov, Xingde Liu, Andy Wai Kan Yeung, Suowen Xu & Atanas G. Atanasov. (2019) Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products. Pharmacological Reviews 71:4, pages 596-670.
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Hayrettin Ozan Gulcan, Serkan Yigitkan & Ilkay Erdogan Orhan. (2019) The Natural Products as Hydroxymethylglutaryl-Coa Reductase Inhibitors. Letters in Drug Design & Discovery 16:10, pages 1130-1137.
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Ying Sun, Yajun Bai, Min Zeng, Xufei Chen, Jing Xie, Bin Li, Xirui He, Yujun Bai, Pu Jia, Xue Meng, Jing Liang, Shixiang Wang, Tai-Ping Fan, Biao Wu & Xiaohui Zheng. (2019) Pharmacokinetics and tissue distribution evaluation of α-asaronol and its main metabolite in rats by HPLC method. Journal of Pharmaceutical and Biomedical Analysis 172, pages 349-356.
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Manuel Serna, Carlos Wong-Baeza, Juan-Carlos Santiago-Hernández, Isabel Baeza & Carlos Wong. (2015) Hypocholesterolemic and choleretic effects of three dimethoxycinnamic acids in relation to 2,4,5-trimethoxycinnamic acid in rats fed with a high-cholesterol/cholate diet. Pharmacological Reports 67:3, pages 553-559.
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. 2014. Essential Oil Safety. Essential Oil Safety 677 755 .
Robert Tisserand & Rodney Young. 2014. Essential Oil Safety. Essential Oil Safety 483 647 .
Ya. F. Kopyt’ko, N. N. Shchurevich, T. A. Sokol’skaya, A. A. Markaryan & T. D. Dargaeva. (2013) Uses, Chemical Composition, and Standardization of Plant Raw Material and Medicinal Substances from Plants of the Genus Asarum L.. Pharmaceutical Chemistry Journal 47:3, pages 157-168.
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