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Feifei Qin, Yali Wang, Xian Jiang, Yujia Wang, Nan Zhang, Xiang Wen, Lian Wang, Qinglin Jiang & Gu He. (2019) Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma. Journal of Enzyme Inhibition and Medicinal Chemistry 34:1, pages 909-926.
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Fisayo Olotu, Emmanuel Adeniji, Clement Agoni, Imane Bjij, Shama Khan, Ahmed Elrashedy & Mahmoud Soliman. (2018) An update on the discovery and development of selective heat shock protein inhibitors as anti-cancer therapy. Expert Opinion on Drug Discovery 13:10, pages 903-918.
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Articles from other publishers (12)
Safa Daoud, Shada J. Alabed, Sanaa K. Bardaweel & Mutasem O. Taha. (2023) Discovery of potent maternal embryonic leucine zipper kinase (MELK) inhibitors of novel chemotypes using structure-based pharmacophores. Medicinal Chemistry Research 32:12, pages 2574-2586.
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Safa Daoud, Reem Abutayeh, Shada J. Alabed & Mutasem O. Taha. (2023) Asenapine as a Potential Lead Inhibitor against Central Ca2+/Calmodulin-Dependent Protein Kinase II: Investigation by Docking Simulation and Experimental Validation. The Open Medicinal Chemistry Journal 17:1.
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Shada J. Alabed, Malek Zihlif & Mutasem Taha. (2022) Discovery of new potent lysine specific histone demythelase-1 inhibitors (LSD-1) using structure based and ligand based molecular modelling and machine learning. RSC Advances 12:55, pages 35873-35895.
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Alaa Abudayah, Safa Daoud, Mahmoud A. Al‐Sha'er & Mutasem Omar Taha. (2022)
Pharmacophore Modeling of Targets Infested with Activity Cliffs
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Molecular Dynamics Simulation Coupled with QSAR and Comparison with other Pharmacophore Generation Methods: KDR as Case Study
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Ayanda M. Magwenyane, Samuel C. Ugbaja, Daniel G. Amoako, Anou M. Somboro, Rene B. Khan & Hezekiel M. Kumalo. (2022) Heat Shock Protein 90 (HSP90) Inhibitors as Anticancer Medicines: A Review on the Computer-Aided Drug Discovery Approaches over the Past Five Years. Computational and Mathematical Methods in Medicine 2022, pages 1-20.
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Lubabah A. Mousa, Ma’mon M. Hatmal & Mutasem Taha. (2022) Exploiting activity cliffs for building pharmacophore models and comparison with other pharmacophore generation methods: sphingosine kinase 1 as case study. Journal of Computer-Aided Molecular Design 36:1, pages 39-62.
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Zhongyuan Zhang, Yujia Tian & Aixia Yan. (2021) SAR study on inhibitors of Hsp90α using machine learning methods. CCF Transactions on High Performance Computing 3:4, pages 353-364.
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Majd S. Hijjawi, Reem Fawaz Abutayeh & Mutasem O. Taha. (2020) Structure-Based Discovery and Bioactivity Evaluation of Novel Aurora-A Kinase Inhibitors as Anticancer Agents via Docking-Based Comparative Intermolecular Contacts Analysis (dbCICA). Molecules 25:24, pages 6003.
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Iman A. Mansi, Mahmoud A. Al-Sha'er, Nizar M. Mhaidat, Mutasem O. Taha & Rand Shahin. (2020) Investigation of Binding Characteristics of Phosphoinositide-dependent Kinase-1 (PDK1) Co-crystallized Ligands Through Virtual Pharmacophore Modeling Leading to Novel Anti-PDK1 Hits. Medicinal Chemistry 16:7, pages 860-880.
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Ghada Omar Tuffaha, Ma'mon M. Hatmal & Mutasem O. Taha. (2019) Discovery of new JNK3 inhibitory chemotypes via QSAR-Guided selection of docking-based pharmacophores and comparison with other structure-based pharmacophore modeling methods. Journal of Molecular Graphics and Modelling 91, pages 30-51.
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Mahmoud A. Al-Sha'er, Rua'a A. Al-Aqtash & Mutasem O. Taha. (2019) Discovery of New Phosphoinositide 3-kinase Delta (PI3Kδ) Inhibitors via Virtual Screening using Crystallography-derived Pharmacophore Modelling and QSAR Analysis. Medicinal Chemistry 15:6, pages 588-601.
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Mahmoud A. Al-Sha'er, Qosay A. Al-Balas, Mohammad A. Hassan, Ghazi A. Al Jabal & Ammar M. Almaaytah. (2019) Combination of pharmacophore modeling and 3D-QSAR analysis of potential glyoxalase-I inhibitors as anticancer agents. Computational Biology and Chemistry 80, pages 102-110.
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