Advanced search
Publication Cover
Journal of Enzyme Inhibition and Medicinal Chemistry Volume 32, 2017 - Issue 1
Submit an article Journal homepage
1,857
Views
10
CrossRef citations to date
0
Altmetric
Research Article

Pharmacophore-based design and discovery of (−)-meptazinol carbamates as dual modulators of cholinesterase and amyloidogenesis

Qiong XieDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, P. R. China; View further author information
,
Zhaoxi ZhengDepartment of Pharmacology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China; View further author information
,
Biyun ShaoDepartment of Pharmacology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China; View further author information
,
Wei FuDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, P. R. China; View further author information
,
Zheng XiaDepartment of Pharmacology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China; View further author information
,
Wei LiDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, P. R. China; View further author information
,
Jian SunDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, P. R. China; View further author information
,
Wei ZhengDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, P. R. China; ;NPFPC Key Laboratory of Contraceptives and Devices, Shanghai Institute of Planned Parenthood Research, Shanghai, P. R. ChinaView further author information
,
Weiwei ZhangDepartment of Pharmacology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China; View further author information
,
Wei ShengDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, P. R. China; View further author information
,
Qihong ZhangDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, P. R. China; View further author information
,
Hongzhuan ChenDepartment of Pharmacology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China; View further author information
,
Hao WangDepartment of Pharmacology, Institute of Medical Sciences, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China; Correspondence[email protected]
View further author information
&
Zhuibai QiuDepartment of Medicinal Chemistry, School of Pharmacy, Fudan University, Shanghai, P. R. China; Correspondence[email protected]
View further author information
 show all
Pages 659-671 | Received 04 Sep 2016, Accepted 25 Oct 2016, Published online: 08 Mar 2017

Citations (10)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Giulia Michels & Matthias Lehr. (2021) High performance liquid chromatographic assays with UV-detection for evaluation of inhibitors of acetylcholinesterase and butyrylcholinesterase. Journal of Liquid Chromatography & Related Technologies 44:5-6, pages 309-319.
Read now

Articles from other publishers (9)

Yash Pal Singh, Navneet Kumar, Brijesh Singh Chauhan & Prabha Garg. (2023) Carbamate as a potential anti‐Alzheimer's pharmacophore: A review. Drug Development Research.
Crossref
Daniel Castro da Costa, Hueldem Ronam Cristo Teixeira, Raí Campos Silva, Isaque Antonio Galindo Francischini, Carlos Henrique Tomich de Paula da Silva & Lorane Izabel da Silva Hage-Melim. (2022) In silico Study of Acetylcholinesterase and Beta-secretase Inhibitors: Potential Multitarget Anti-Alzheimer’s Agents . Central Nervous System Agents in Medicinal Chemistry 22:2, pages 139-150.
Crossref
Wen-Ying Liu, Xiao-Wen Feng, Qing-Li Cheng, Xiao-Han Zhao, Guo-Ming Li & Rui-Zeng Gu. (2021) Identification and action mechanism of low-molecular-weight peptides derived from Atlantic salmon (Salmo salar L.) skin inhibiting angiotensin I–converting enzyme. LWT 150, pages 111911.
Crossref
Pratibha Magar, Oscar Parravicini, Šárka Štěpánková, Katarina Svrčková, Adriana D. Garro, Izabela Jendrzejewska, Karel Pauk, Jan Hošek, Josef Jampílek, Ricardo D. Enriz & Aleš Imramovský. (2021) Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE. International Journal of Molecular Sciences 22:17, pages 9447.
Crossref
Mohammad Shahrivar‐Gargari, Maryam Hamzeh‐Mivehroud, Salar Hemmati, Javid S. Mojarrad, Tuba Tüylü Küçükkılınç, Beyza Ayazgök & Siavoush Dastmalchi. (2021) Hybridization‐based design of novel anticholinesterase indanone–carbamates for Alzheimer's disease: Synthesis, biological evaluation, and docking studies. Archiv der Pharmazie 354:7.
Crossref
Tereza Padrtová, Pavlína Marvanová, Renáta Kubínová, Jozef Csöllei, Oldřich Farsa, Tomáš Goněc, Klára Odehnalová, Radka Opatřilová, Jiří Pazourek, Alice Sychrová, Karel Šmejkal & Petr Mokrý. (2020) Indol-2-Carboxylic Acid Esters Containing N-Phenylpiperazine Moiety - Preparation and Cholinesterase-inhibiting Activity. Current Organic Synthesis 17:7, pages 576-587.
Crossref
Wen-Yan Jin, Ying Ma, Wei-Ya Li, Hong-Lian Li & Run-Ling Wang. (2018) Scaffold-based novel SHP2 allosteric inhibitors design using Receptor-Ligand pharmacophore model, virtual screening and molecular dynamics. Computational Biology and Chemistry 73, pages 179-188.
Crossref
Amit Kumar Halder, Ana S. Moura & M. Natália D. S. Cordeiro. 2019. Multi-Target Drug Design Using Chem-Bioinformatic Approaches. Multi-Target Drug Design Using Chem-Bioinformatic Approaches 155 186 .
Tereza Padrtova, Pavlina Marvanova, Klara Odehnalova, Renata Kubinova, Oscar Parravicini, Adriana Garro, Ricardo Enriz, Otakar Humpa, Michal Oravec & Petr Mokry. (2017) Synthesis, Analysis, Cholinesterase-Inhibiting Activity and Molecular Modelling Studies of 3-(Dialkylamino)-2-hydroxypropyl 4-[(Alkoxy-carbonyl)amino]benzoates and Their Quaternary Ammonium Salts. Molecules 22:12, pages 2048.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.